ELL1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ELL1_SCHPO
• UniProt AC: Q9P7X2
• Protein Name: RNA polymerase II elongation factor ell1
• Gene Name: ell1 {ECO:0000312|EMBL:CAB66442.1}
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 533
• Subcellular Localization: Nucleus .
• Protein Description: Activates transcription elongation by RNA polymerase II and pyrophosphorolysis as a complex with eaf1. Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA..
• Protein Sequence: MIRNSSISDALPVALGGNEEESPLLMLVQLPKEFLEGYLSGTITDVSLECSDVGTSILANDRSYKCTSVPETAPHEIYRLVDSNSLQLVGRVSQKLQLRRELDSLTAERVKNRTQEAQKEKEEKRIVTLQNDGGSKNTTARKQKQLKKNGLRPLNTSASRIGLSSSPTNTPSPNLPVSQPSASPHYSGDKNSAKGIDLRTRVIQLLAIAPETEDFLRLRTKASLSKLQALLPEVAWKNNMNQWELLNPVYKDVRVFDWRPYSIADRNAVLSRMSNAFDNMQLPPDAPERSLLVSKQKNITKLNNEKRIPPQLAQPTSHVPSFIDTNSPSMPSISSVSSYQQQHRIPKLNASNYSPLLSPSSHRKTSGNLSRTGSESSAVSLSDTTNLNTPISDIPSPGSSTTCSNLSSPHIKRKSRSPPQSLPSTPFPTSSSSTNGTLEPNANSPKKNEQDAWIAKKRRQQRYTTEEMRALAKRFRETYPRYKNLYLKVSSYYDNNDTNNPNLNKLQDELISLHSQLKSWKNTLYDASSELAL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
164	Phosphorylation	SASRIGLSSSPTNTP CHHHHCCCCCCCCCC	24.45	29996109
166	Phosphorylation	SRIGLSSSPTNTPSP HHHCCCCCCCCCCCC	32.16	29996109
168	Phosphorylation	IGLSSSPTNTPSPNL HCCCCCCCCCCCCCC	54.39	29996109
181	Phosphorylation	NLPVSQPSASPHYSG CCCCCCCCCCCCCCC	33.47	29996109
183	Phosphorylation	PVSQPSASPHYSGDK CCCCCCCCCCCCCCC	19.29	29996109
186	Phosphorylation	QPSASPHYSGDKNSA CCCCCCCCCCCCCCC	20.10	29996109
325	Phosphorylation	HVPSFIDTNSPSMPS CCCCCCCCCCCCCCC	32.55	29996109
329	Phosphorylation	FIDTNSPSMPSISSV CCCCCCCCCCCCHHC	43.05	29996109
351	Phosphorylation	RIPKLNASNYSPLLS CCCCCCCCCCCCCCC	34.92	28889911
353	Phosphorylation	PKLNASNYSPLLSPS CCCCCCCCCCCCCCC	14.79	25720772
354	Phosphorylation	KLNASNYSPLLSPSS CCCCCCCCCCCCCCC	17.20	21712547
358	Phosphorylation	SNYSPLLSPSSHRKT CCCCCCCCCCCCCCC	30.34	28889911
360	Phosphorylation	YSPLLSPSSHRKTSG CCCCCCCCCCCCCCC	35.09	21712547
361	Phosphorylation	SPLLSPSSHRKTSGN CCCCCCCCCCCCCCC	30.60	25720772
415	Phosphorylation	SPHIKRKSRSPPQSL CCCCCCCCCCCCCCC	41.86	24763107
417	Phosphorylation	HIKRKSRSPPQSLPS CCCCCCCCCCCCCCC	48.28	28889911
433	Phosphorylation	PFPTSSSSTNGTLEP CCCCCCCCCCCCCCC	28.04	27738172
444	Phosphorylation	TLEPNANSPKKNEQD CCCCCCCCCCCCHHH	35.37	27738172

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ELL1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ELL1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ELL1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RPB1_SCHPO	rpb1	physical	17150956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.