dbPTM

SST6_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SST6_SCHPO
UniProt AC	Q7Z992
Protein Name	ESCRT-I complex subunit vps23
Gene Name	sst6
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	487
Subcellular Localization	Cytoplasm . Endosome . Late endosome membrane Peripheral membrane protein.
Protein Description	Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association to the ESCRT-0 complex (By similarity)..
Protein Sequence	MSDHAINEHPSRILNTIEKIRFWKNGLAEELELLFRKQCEDTFTLQAINIEVDTQDENKIEEVRIYLSTPAFDKTILTSACITVRSYYPSQPPIVQLLDEKGGKHKYTSLLLQLWKNERSVFNIYRLVQALIKQDFEREHTSPPELPTKLVNTIEKLKVKEENEAPPVIPAKPFSSSSEQHFRKVPALPSKLPPKPLKITANSSLGQETNSNSSSFQSTLFSLNTAPFSATSQQLVHDSVSLRRPSSNIPAQKPIPPKPEQNEIIITKDTPSLKDKYSKPALLPQKPKVSKGQIVQQVSVFSTGKKIESQSLLNLIDTDIETPLKGSSELLYSEDFKPNVDPVKIQQILHKQNKIIEEKWISQIRISKNLEVKQRLLDQERHALETLAKNIENNRFILGKRRRKAREALQKLDNLKDLSVQELFIIPSERELKYYELKRKDEKLDEGIRALNQALHHESIMPASWLKGIKLLARQQFLIRDEMLQYS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
2	Phosphorylation	------MSDHAINEH ------CCCCHHHCC	37.80	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SST6_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SST6_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SST6_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
CBH1_SCHPO	cbh1	physical	26771498
CLR3_SCHPO	clr3	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SST6_SCHPO

Related Literatures of Post-Translational Modification