ALG5_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ALG5_SCHPO
• UniProt AC: O60061
• Protein Name: Dolichyl-phosphate beta-glucosyltransferase
• Gene Name: alg5
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 322
• Subcellular Localization: Endoplasmic reticulum membrane ; Single-pass type II membrane protein . Its interaction with the substrate UDP-glucose may occur at the cytoplasmic side of the ER, whereas the steps utilizing dolichyl beta-D-glucosyl phosphate take place in the lumen
• Protein Sequence: MVVYIVLYTCLAGFILLFLVYYYLTHSHCPRKQLEGEETCVFIENGQKKSLTLEKWSTSDNIQITVIVPAYNESKRIGNMLQETVDHLEKYYRSSSSAGQRRWEILIVDDESKDTTVNAVLEFSNKLDLRDHLRVCSLKRNRGKGGAVTWGMLYARGQYAIFADADGASQFSDLELLFKNMPPGPRGGVVVGSRAHMVNTAAVVKRSFIRNFLMHCFHKLLQILGIREIGDTQCGFKLFSREAYQSIFPRMHVEGWIFDIEVLTLARFFGLPIIEVPITWHEVGGSKMTLLKDSISMAIDLLVIRLNYTFGIWERPSAKRIT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
72	N-linked_Glycosylation	TVIVPAYNESKRIGN EEEEECCCCCHHHHH	49.53	-
307	N-linked_Glycosylation	DLLVIRLNYTFGIWE HHHHHHHCCEEEECC	24.77	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ALG5_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ALG5_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ALG5_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PST2_SCHPO	pst2	genetic	19547744

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.