PST2_SCHPO - dbPTM
PST2_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PST2_SCHPO
UniProt AC O13919
Protein Name Paired amphipathic helix protein pst2
Gene Name pst2
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 1075
Subcellular Localization Nucleus .
Protein Description Has a role in chromatin assembly and chromosome segregation. Involved in the deacetylation of histones..
Protein Sequence MEQTLAILKNDNSTLVAEMQNQLVHDFSPNGTALPELDIKAFVQKLGQRLCHRPYVYSAFMDVVKALHNEIVDFPGFIERISVILRDYPDLLEYLNIFLPSSYKYLLSNSGANFTLQFTTPSGPVSTPSTYVATYNDLPCTYHRAIGFVSRVRRALLSNPEQFFKLQDSLRKFKNSECSLSELQTIVTSLLAEHPSLAHEFHNFLPSSIFFGSKPPLGSFPLRGIQSSQFTLSNISDLLSQSRPDNLSPFSHLSNESSDFFKNVKNVLTDVETYHEFLKLLNLYVQGIIDRNILVSRGFGFLKSNSGLWRSFLSLTSLSPEEFLSVYNSACSDFPECGPSYRLLPVEERNISCSGRDDFAWGILNDDWVSHPTWASEESGFIVQRKTPYEEAMTKLEEERYEFDRHIEATSWTIKSLKKIQNRINELPEEERETYTLEEGLGLPSKSIYKKTIKLVYTSEHAEEMFKALERMPCLTLPLVISRLEEKNEEWKSVKRSLQPGWRSIEFKNYDKSLDSQCVYFKARDKKNVSSKFLLAEADILRSQAKLHFPLRSRSAFEFSFVYDNEIVLFDTCYMVCTYIVCNSPSGLKKVEHFFKNILPLHFGLEKDKFSIFLDQVFRGPDYDVNAPNIVGNKPVRRKRSNSITQLTEFVKQPKINGQRESRSAAAARKKEESGNKSQSNSQNSLSDESGNVTPVSKKQLSQPAAAIKASLKYPSHPDSLLEHQDHAGDTENEMHDDVDKEQFGYSSMYVFFRLFNLLYERLYELQRLEDQVSIIQQRIIPNPVSQKQKIWRDRWNDLSDVPDEKTHYENTYVMILRLIYGIVDQSAFEDYLRFYYGNKAYKIYTIDKLVWSAAKQVHHIVSDGKYKFVTSLVEQNSSASPKKNYDDFLYRLEIEKLLNPDEILFRFCWINKFKSFGIKIMKRANLIVDQSLDTQRRVWKKYVQNYRIQKLTEEISYKNYRCPFLCRNIEKERTVEQLVSRLQTKLLRSAELVSGLQAKLCLDSFKLLYLPRTEDSYIDASYLRLRDTDFLDCQNKRKQRWRNRWESLLKSVRGTSDNTAEVNFDADINALFIP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
14PhosphorylationILKNDNSTLVAEMQN
ECCCCCCHHHHHHHH
31.3521712547
28PhosphorylationNQLVHDFSPNGTALP
HHHHCCCCCCCCCCC
24.4221712547
32PhosphorylationHDFSPNGTALPELDI
CCCCCCCCCCCCCCH
31.4921712547
641PhosphorylationKPVRRKRSNSITQLT
CCCCCCCCCCHHHHH
37.6528889911
643PhosphorylationVRRKRSNSITQLTEF
CCCCCCCCHHHHHHH
28.4128889911
645PhosphorylationRKRSNSITQLTEFVK
CCCCCCHHHHHHHHH
19.8321712547
685PhosphorylationSQSNSQNSLSDESGN
CCCCCCCCCCCCCCC
22.9329996109
687PhosphorylationSNSQNSLSDESGNVT
CCCCCCCCCCCCCCC
38.8721712547
694PhosphorylationSDESGNVTPVSKKQL
CCCCCCCCCCCHHHH
23.2129996109
878PhosphorylationTSLVEQNSSASPKKN
EHHHHCCCCCCCCCC
27.2924763107
881PhosphorylationVEQNSSASPKKNYDD
HHCCCCCCCCCCHHH
38.9228889911
957PhosphorylationQKLTEEISYKNYRCP
HHHHHHHHCCCCCCC
33.0829996109
958PhosphorylationKLTEEISYKNYRCPF
HHHHHHHCCCCCCCC
14.6529996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PST2_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PST2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PST2_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RSC1_SCHPOrsc1genetic
19547744
RSV1_SCHPOrsv1genetic
19547744
RAP1_SCHPOrap1genetic
19547744
REC14_SCHPOrec14genetic
19547744
TIM13_SCHPOtim13genetic
19547744
RSV2_SCHPOrsv2genetic
19547744
PUB2_SCHPOpub2genetic
19547744
GMA12_SCHPOgma12genetic
19547744
CSK2C_SCHPOckb2genetic
19547744
YDBJ_SCHPOsnt1genetic
19547744
GCN5_SCHPOgcn5genetic
19547744
CENPA_SCHPOcnp1genetic
23028377
DHE4_SCHPOgdh1genetic
22681890
DPH2_SCHPOdph2genetic
22681890
YQE1_SCHPOxan1genetic
22681890
MEI2_SCHPOmei2genetic
22681890
VHT1_SCHPOvht1genetic
22681890
YHJ1_SCHPOSPBPB10D8.01genetic
22681890
PDP2_SCHPOSPBC215.07cgenetic
22681890
FHL1_SCHPOfhl1genetic
22681890
YHZ8_SCHPOSPBC21B10.08cgenetic
22681890
FLP1_SCHPOclp1genetic
22681890
FIN1_SCHPOfin1genetic
22681890
REB1_SCHPOreb1genetic
22681890
RL28B_SCHPOrpl2801genetic
22681890
FIS1_SCHPOfis1genetic
22681890
YQ7B_SCHPOSPCC1442.11cgenetic
22681890
YGA3_SCHPOSPBC6B1.03cgenetic
22681890
ALY2_SCHPOSPBC2D10.04genetic
22681890
MU121_SCHPOmug121genetic
22681890
SNF59_SCHPOsnf59genetic
22681890
BQT4_SCHPObqt4genetic
22681890
FEN1_SCHPOrad2genetic
22681890
6PGL_SCHPOSPCC16C4.10genetic
22681890
PAC2_SCHPOpac2genetic
22681890
YN1B_SCHPOSPBC577.11genetic
22681890
YIN2_SCHPOSPAC1705.02genetic
22681890
CEK1_SCHPOcek1genetic
22681890
YCJD_SCHPOSPCC63.13genetic
22681890
YM06_SCHPOSPAC212.06cgenetic
22681890
YLZ1_SCHPOSPAC750.01genetic
22681890
YCGK_SCHPOSPCC16C4.20cgenetic
22681890
UREA_SCHPOure2genetic
22681890
PYP1_SCHPOpyp1genetic
22681890
IMA3_SCHPOSPCC550.11genetic
22681890
YEM8_SCHPOclr5genetic
22681890
YFY2_SCHPOSPAC9.02cgenetic
22681890
LDH_SCHPOSPAC186.08cgenetic
22681890
G6PD2_SCHPOzwf2genetic
22681890
SUT1_SCHPOsut1genetic
22681890
YBQ3_SCHPOSPBC115.03genetic
22681890
YJ52_SCHPOSPCP20C8.02cgenetic
22681890
FIO1_SCHPOfio1genetic
22681890
AP3M_SCHPOapm3genetic
22681890
FRP2_SCHPOfrp2genetic
22681890
ATG7_SCHPOatg7genetic
22681890
YN8E_SCHPOSPBP35G2.14genetic
22681890
MGR2_SCHPOmgr2genetic
22681890
IES4_SCHPOies4genetic
22681890
YJNG_SCHPOSPCC24B10.16cgenetic
22681890
MUG16_SCHPOmug16genetic
22681890
GYP7_SCHPOgyp7genetic
22681890
RL25B_SCHPOrpl2502genetic
22681890
PLB2_SCHPOSPAC1A6.03cgenetic
22681890
MU147_SCHPOmug147genetic
22681890
YF69_SCHPOSPAC23C4.09cgenetic
22681890
UBC16_SCHPOubc16genetic
22681890
UBP11_SCHPOubp11genetic
22681890
YI41_SCHPOSPBCPT2R1.01cgenetic
22681890
YP41_SCHPOSPBCPT2R1.01cgenetic
22681890
PPK8_SCHPOppk8genetic
22681890
TRMB_SCHPOtrm8genetic
22681890
YF3H_SCHPOSPAC22A12.17cgenetic
22681890
GTI1_SCHPOgti1genetic
22681890
PYR1_SCHPOura1genetic
22681890
PPA1_SCHPOpho1genetic
22681890
YHS6_SCHPOSPBC947.06cgenetic
22681890
POP2_SCHPOpop2genetic
22681890
YLV1_SCHPOSPAC2H10.01genetic
22681890
SRR_SCHPOsry1genetic
22681890
PPR2_SCHPOppr2genetic
22681890
YGBA_SCHPOSPBC25B2.10genetic
22681890
SEL1_SCHPOsle1genetic
22681890
GCN5_SCHPOgcn5genetic
22681890
MU113_SCHPOmug113genetic
22681890
YAJE_SCHPOSPAC30D11.14cgenetic
22681890
DYLT_SCHPOdlc1genetic
22681890
DCTD_SCHPOdcd1genetic
22681890
YAOG_SCHPOSPAC11D3.16cgenetic
22681890
TMA20_SCHPOtma20genetic
22681890
ZRG17_SCHPOzrg17genetic
22681890
KA113_SCHPOkap113genetic
22681890
SWC3_SCHPOswc3genetic
22681890
THI5_SCHPOthi5genetic
22681890
UBC13_SCHPOubc13genetic
22681890
NAGS_SCHPOarg6genetic
22681890
NAA35_SCHPOmak10genetic
22681890
DPOZ_SCHPOrev3genetic
22681890
QCR8_SCHPOqcr8genetic
22681890
GLYD_SCHPOSPAC24C9.12cgenetic
22681890
NTA1_SCHPOnta1genetic
22681890
YEG7_SCHPOSPAC26H5.07cgenetic
22681890
ATP12_SCHPOatp12genetic
22681890
ASH2_SCHPOash2genetic
22681890
GLRX3_SCHPOgrx3genetic
22681890
YKN2_SCHPOSPAPB1A11.02genetic
22681890
FSV1_SCHPOfsv1genetic
22681890
PSL1_SCHPOpsl1genetic
22681890
HOSM_SCHPOlys4genetic
22681890
GBB_SCHPOgit5genetic
22681890
IF5A2_SCHPOtif512genetic
22681890
CTL1_SCHPOctl1genetic
22681890
YEAB_SCHPOmpp6genetic
22681890
YI7H_SCHPOSPAC977.17genetic
22681890
DCOR_SCHPOspe1genetic
22681890
SCS7_SCHPOscs7genetic
22681890
TLS1_SCHPOtls1genetic
22681890
PUT2_SCHPOSPBC24C6.04genetic
22681890
HNT1_SCHPOhnt1genetic
22681890
YLX4_SCHPOSPAC922.04genetic
22681890
PTR2_SCHPOptr2genetic
22681890
THT2_SCHPOtht2genetic
22681890
YFM8_SCHPOSPAC222.08cgenetic
22681890
YCS3_SCHPOSPCC613.03genetic
22681890
RS25A_SCHPOrps2502genetic
22681890
ABC4_SCHPOabc4genetic
22681890
YHEH_SCHPOSPBPB2B2.17cgenetic
22681890
AROG_SCHPOSPAP8A3.07cgenetic
22681890
YKH3_SCHPOsyn1genetic
22681890
YHE7_SCHPOSPBPB2B2.07cgenetic
22681890
NSK1_SCHPOnsk1genetic
22681890
DIOXL_SCHPOSPBC1709.16cgenetic
22681890
YJM5_SCHPOSPCC1020.05genetic
22681890
IRS4_SCHPOSPAC1687.09genetic
22681890
YOR2_SCHPOrng9genetic
22681890
YOD2_SCHPOSPBC18A7.02cgenetic
22681890
YNW5_SCHPOyar1genetic
22681890
CYB51_SCHPOSPBC29A10.16cgenetic
22681890
ERS1_SCHPOers1genetic
22681890
PPZ_SCHPOpzh1genetic
22681890
EXG1_SCHPOexg1genetic
22681890
MUG65_SCHPOmug65genetic
22681890
YAG9_SCHPOSPAC12G12.09genetic
22681890
ABC3_SCHPOabc3genetic
22681890
CIP2_SCHPOcip2genetic
22681890
YGD3_SCHPOSPBC1773.03cgenetic
22681890
YLY6_SCHPOSPAC186.06genetic
22681890
RAF1_SCHPOraf1genetic
22681890
YII1_SCHPOSPAC139.01cgenetic
22681890
YA7B_SCHPOSPAC24H6.11cgenetic
22681890
ERFD_SCHPOerf4genetic
22681890
YL39_SCHPOSPAC1071.09cgenetic
22681890
SET1_SCHPOset1genetic
22681890
GMA12_SCHPOgma12genetic
22681890
YOD1_SCHPOSPBC18A7.01genetic
22681890
RENT1_SCHPOupf1genetic
22681890
MNL1_SCHPOmnl1genetic
22681890
IQW1_SCHPOiqw1genetic
22681890
APE1_SCHPOape2genetic
22681890
SHR3_SCHPOpsh3genetic
22681890
BIOB_SCHPObio2genetic
22681890
YCY1_SCHPOSPCC1235.01genetic
22681890
YHC3_SCHPOyap18genetic
22681890
SULH2_SCHPOSPAC869.05cgenetic
22681890
YBW4_SCHPOSPBC651.04genetic
22681890
WOS2_SCHPOwos2genetic
22681890
RAP1_SCHPOrap1genetic
22681890
YQO4_SCHPOSPCC569.04genetic
22681890
VAC7_SCHPOvac7genetic
22681890
YGNJ_SCHPOalb1genetic
22681890
RGA3_SCHPOrga3genetic
22681890
YCB5_SCHPOSPCC61.05genetic
22681890
RGA6_SCHPOrga6genetic
22681890
SUM2_SCHPOsum2genetic
22681890
RS17A_SCHPOrps1701genetic
22681890
IVN1_SCHPOivn1genetic
22681890
SIF3_SCHPOsif3genetic
22681890
MUG94_SCHPOmug94genetic
22681890
YKN4_SCHPOmca1genetic
22681890
IWR1_SCHPOiwr1genetic
22681890
PPK25_SCHPOppk25genetic
22681890
YJ61_SCHPOSPCC1884.01genetic
22681890
MAP1_SCHPOfma1genetic
22681890
CIS4_SCHPOcis4genetic
22681890
TBA2_SCHPOatb2genetic
22681890
GST1_SCHPOgst1genetic
22681890
TCP4_SCHPOsub1genetic
22681890
LGUL_SCHPOglo1genetic
22681890
VAC14_SCHPOSPBC25H2.03genetic
22681890
YHZ7_SCHPOSPBC21B10.07genetic
22681890
SPM1_SCHPOpmk1genetic
22681890
CTU2_SCHPOctu2genetic
22681890
PRS10_SCHPOrpt4genetic
22681890
RL19B_SCHPOrpl1902genetic
22681890
YHEB_SCHPOSPBPB2B2.11genetic
22681890
MPC1_SCHPOmpc1genetic
22681890
YBN5_SCHPOSPBC8E4.05cgenetic
22681890
YI4C_SCHPOSPBC1348.12genetic
22681890
SPN2_SCHPOspn2genetic
22681890
KLP6_SCHPOklp6genetic
22681890
YFE6_SCHPOgmh5genetic
22681890
PMT1M_SCHPOpmt1genetic
22681890
AREH2_SCHPOare2genetic
22681890
FYV10_SCHPOSPBC106.13genetic
22681890
CLR1_SCHPOclr1genetic
22681890
YCV2_SCHPOSPCC777.02genetic
22681890
YKEE_SCHPOSPAC1805.14genetic
22681890
TSC1_SCHPOtsc1genetic
22681890
GPD2_SCHPOgpd2genetic
22681890
PPK29_SCHPOppk29genetic
22681890
YGK5_SCHPOSPBC725.05cgenetic
22681890
YEAA_SCHPOSPACUNK4.10genetic
22681890
YNT3_SCHPOSPBC9B6.03genetic
22681890
CAF5_SCHPOcaf5genetic
22681890
YQK8_SCHPOSPCC1494.08cgenetic
22681890
LYS12_SCHPOlys12genetic
22681890
RS4A_SCHPOrps401genetic
22681890

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PST2_SCHPO

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-641 AND SER-643, ANDMASS SPECTROMETRY.

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