dbPTM

SULH2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SULH2_SCHPO
UniProt AC	Q9URY8
Protein Name	Probable sulfate permease C869.05c
Gene Name	SPAC869.05c
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	840
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description	High affinity uptake of sulfate into the cell..
Protein Sequence	MRAWGWVRNKFSSEDDYNDGASNKDYPDRFNEFDNSQNDHNDYTQNNAQFQNAQTTTFGRTISRVKAYYEIPEDDELDELASIPQWFKKNVTSNIFKNFLHYLKSLFPIIEWLPNYNPYWLINDLIAGITVGCVVVPQGMSYAKVATLPSEYGLYSSFVGVAIYCFFATSKDVSIGPVAVMSLITAKVIANVMAKDETYTAPQIATCLALLAGAITCGIGLLRLGFIIEFIPVPAVAGFTTGSALNILSGQVPALMGYKNKVTAKATYMVIIQSLKHLPDTTVDAAFGLVSLFILFFTKYMCQYLGKRYPRWQQAFFLTNTLRSAVVVIVGTAISYAICKHHRSDPPISIIKTVPRGFQHVGVPLITKKLCRDLASELPVSVIVLLLEHISIAKSFGRVNDYRIVPDQELIAMGVTNLIGIFFNAYPATGSFSRSAIKAKAGVKTPIAGIFTAAVVILSLYCLTDAFYYIPNAILSAVIIHAVTDLILPMKQTILFWRLQPLEACIFFISVIVSVFSSIENGIYVSVCLAAALLLLRIAKPHGSFLGKIQAANKYGSDNIANVRDIYVPLEMKEENPNLEIQSPPPGVFIFRLQESFTYPNASRVSTMISRRIKDLTRRGIDNIYVKDIDRPWNVPRQRKKKENSEIEDLRPLLQAIIFDFSAVNNLDTTAVQSLIDIRKELEIYANETVEFHFTNIRSGWIKRTLVAAGFGKPKGHAVDASVCVEVAAPLRDANLSAESSRNLSRIITPIYDDEEGNVSGHIYELDGKNNSDLSMHCQKGSNQVEIEFVEFNSRKYPFFHVDVASAVVDLQHRLLSPQKSDSFGSLKEGGTTTIKKIEN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
22	Phosphorylation	DDYNDGASNKDYPDR CCCCCCCCCCCCCCC	50.36	24763107
737	Phosphorylation	PLRDANLSAESSRNL CCCCCCCCHHHHCCH	29.78	25720772
740	Phosphorylation	DANLSAESSRNLSRI CCCCCHHHHCCHHHC	34.02	25720772
741	Phosphorylation	ANLSAESSRNLSRII CCCCHHHHCCHHHCE	19.38	25720772
745	Phosphorylation	AESSRNLSRIITPIY HHHHCCHHHCEEEEE	25.61	25720772
749	Phosphorylation	RNLSRIITPIYDDEE CCHHHCEEEEECCCC	10.97	29996109
760	Phosphorylation	DDEEGNVSGHIYELD CCCCCCEEEEEEEEC	28.75	29996109
772	Phosphorylation	ELDGKNNSDLSMHCQ EECCCCCCCCHHHCC	49.69	24763107
775	Phosphorylation	GKNNSDLSMHCQKGS CCCCCCCHHHCCCCC	16.09	21712547
821	Phosphorylation	RLLSPQKSDSFGSLK HHHCCCCCCCCCCCC	32.99	25720772
823	Phosphorylation	LSPQKSDSFGSLKEG HCCCCCCCCCCCCCC	38.30	28889911
826	Phosphorylation	QKSDSFGSLKEGGTT CCCCCCCCCCCCCEE	33.97	24763107
832	Phosphorylation	GSLKEGGTTTIKKIE CCCCCCCEEEEEECC	31.46	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SULH2_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SULH2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SULH2_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of SULH2_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SULH2_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-823, AND MASSSPECTROMETRY.	18257517 [Abstract]