YAG9_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YAG9_SCHPO
• UniProt AC: Q09872
• Protein Name: Uncharacterized protein C12G12.09
• Gene Name: SPAC12G12.09
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 977
• Protein Sequence: MSFYKEKSINETNLGSFVDESNELFFSALSESSMNHGTPDDSILLDLVSRSDNKDLYQDSLDVRDNFSNLSSDEIPQSSSYEQTRKPFFHHFNPFEFLEATSPLQQNGKSRDTEKPPSMKEKDLSSNSSSQHDKAFHERVDQGKNKSSTTKYQEFRTVADYREFSPGQSVNSLKPNSGDEVPSTKSSTSSEMHTQLLKDEQKKILTPAPDVPHDVYCIEPSLGRVFSFPASFVASPLLLEDCNKIASCDLPYSTFYANSQVIDKFSEYFAYVDQDPCHIRVLNANTDQSLILYTQSDVKNLHFGKNKHTKPHLLVMDALSNLYVWKILQKRSEISVSLLFTIRRANYGICDWIPNSSNMFSMIVKNSLYIVDISNIRSNNISPKVYAKDFNGLQAAKVDLPGPINSYTISSDRSVVAILVNSQIFFYSFPVSNLFSTNPSHRGNWAAIATMSLQLPSTANSISFLSSPPNNNDIIDKVICVSYANNTILGLFDFGLCAFTQEIEFSNEKEKSPIQQLLTFNNSNMIVAKRNQLLDIFIYSPSDLSNVGVLSNTAALISAVSKGKRFGDSGYINKVISNEVVDHSIVFVTLIGCDSSKLELILALSSGYFQFCIESDSKFDEGTSLEYPNSDKRILARASLTSGLKSNNTLRALSQDLKNCAKSKDDSTTQNLTESLGSVCYPSMPFFNQYVPQNPNEVRENISSVMKSRIHAKFESLHSRVELVVKNSYMKLLEQTISEAATDEISDLFKLIHSKPFLLEVGFLETGFLANDLENLTSTYRSSNRQLCDFSNRIGNINQKLEKLLMIERLETSDQSPTSSSNFEESESFAVSKKVLELVRISKNKEALICFTKDPSIEAFRSLQDVPDYSLDDCSSIHLLAFIHVLSKLIIKEEQLSFSRLQLLSRATSRLRTMTLSVFNNSGTLTPELFSSVVRIVLKNVREFVLIGNSSIQKSKHEFLITTLQALLREVDIFLNT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
51	Phosphorylation	LLDLVSRSDNKDLYQ HHHHHCCCCCCCHHH	37.72	25720772
57	Phosphorylation	RSDNKDLYQDSLDVR CCCCCCHHHHCCHHH	22.02	25720772
60	Phosphorylation	NKDLYQDSLDVRDNF CCCHHHHCCHHHHHC	15.79	29996109
68	Phosphorylation	LDVRDNFSNLSSDEI CHHHHHCCCCCCCCC	43.02	21712547
71	Phosphorylation	RDNFSNLSSDEIPQS HHHCCCCCCCCCCCC	39.74	25720772
72	Phosphorylation	DNFSNLSSDEIPQSS HHCCCCCCCCCCCCC	42.29	29996109
118	Phosphorylation	RDTEKPPSMKEKDLS CCCCCCCCCCHHHCC	51.52	29996109
125	Phosphorylation	SMKEKDLSSNSSSQH CCCHHHCCCCCCCHH	37.29	21712547
126	Phosphorylation	MKEKDLSSNSSSQHD CCHHHCCCCCCCHHH	48.29	25720772
128	Phosphorylation	EKDLSSNSSSQHDKA HHHCCCCCCCHHHHH	33.06	21712547
129	Phosphorylation	KDLSSNSSSQHDKAF HHCCCCCCCHHHHHH	37.96	21712547
130	Phosphorylation	DLSSNSSSQHDKAFH HCCCCCCCHHHHHHH	31.21	21712547
157	Phosphorylation	TKYQEFRTVADYREF HHHHEEEEHHCCCCC	25.93	24763107
161	Phosphorylation	EFRTVADYREFSPGQ EEEEHHCCCCCCCCC	11.42	21712547
165	Phosphorylation	VADYREFSPGQSVNS HHCCCCCCCCCCCCC	24.30	28889911
169	Phosphorylation	REFSPGQSVNSLKPN CCCCCCCCCCCCCCC	29.22	21712547
188	Phosphorylation	VPSTKSSTSSEMHTQ CCCCCCCCCHHHHHH	43.28	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YAG9_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YAG9_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YAG9_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
XRN1_SCHPO	exo2	physical	24755092
DCP2_SCHPO	dcp2	physical	26771498
PRP40_SCHPO	usp104	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-165, AND MASSSPECTROMETRY.
PubMed: 18257517