dbPTM

THI5_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	THI5_SCHPO
UniProt AC	O94278
Protein Name	Thiamine repressible genes regulatory protein thi5
Gene Name	thi5
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	857
Subcellular Localization	Nucleus .
Protein Description	Transcription factor that activates the nmt1 promoter. Regulation of thiamine repressible genes. Negatively regulates conjugation during meiosis, by inducing negative regulators which delay conjugation. Involved in thi1 regulation..
Protein Sequence	MCPSDFSSRSLFLEAKEEEYKQRRRVPLDSRRRVRRACLSCRAKKIRCSGSEPCQACIATPSQCKYADSLKERTPSKQFIAELSQRQKCFEYLMELLCPSLPHDTRSLVKLCKHVESSLASGSDVRSLLIPGSIDQSVLKVAATNNKDDSSAVKSANVSFPSSSTPPSSDSNFSSIQNTDLNTSIKFTENISANAIHVNQDKVIRSANNLIINSQPILPVRSFLDALGEPIYLSPTSSTYFLNSVLASLQLNSSNTPESLLIDYQSKIPEDLSSSLLPLELNTLQSTPTSVSVGSASSQGTHEYSIINLTSNHSSFSLKALKKIAHNLLPPVSVAERYANEFFLRYQSFFYFYPPSVFSNRYQILADGLVNSDTLDTGFLAVALLIVVLGHFSNNNINVLPKEVQLSHIDSMIQISEQLISSLLNRCTLSSIQAVFLLSLYHFLTGNFKCAYSYLGFAIHSAHTLGLEHGSTDNSTLNEVSTEETSIRICWSLRVLASFLYIQSGITPIINLFPNGLNSLKLPTVVPELEARHLPSSVFHFVAIIKYAEISVRSLNSLYESSSDYLMDVSNFPKLLLKVERIYSQARNWKLNLTHQQLNGTNDTSDLLFHSNVSLHLFYHYLIVKVSCPIMFFYLNNWYSVKPSSFTKGLNNKPSLEDVFSNLETCYESAKAIVQLSSKLLSAGQMDKCFYLEFEILYCSAIVLFLFSVMHLGAENPLLESIYLLEDMGSRTIDSKVRLEKLKSAIEIFDINSATEMPINEPLSASFESVNKENSQSGYMAWQNWVTELSSSNIPLGHALGNPESNNSSNSFKPSHPSQSFLVNESLDFSSNPKEPPFLPWSEALLNMDMQLNRLGP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of THI5_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of THI5_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of THI5_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of THI5_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of THI5_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of THI5_SCHPO

Related Literatures of Post-Translational Modification