SPN2_SCHPO - dbPTM
SPN2_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID SPN2_SCHPO
UniProt AC Q09116
Protein Name Septin homolog spn2
Gene Name spn2
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 331
Subcellular Localization Cytoplasm, cell cortex. Forespore membrane
Peripheral membrane protein. Localizes to the medial ring at the cell cortex of dividing cells. The sporulation-specific septin complex associates to the forespore membrane and forms partial or complete rin
Protein Description Plays a role in the cell cycle. Involved in a late stage of septum formation leading to the separation of the daughter cells. Involved in the correct orientation of forespore membrane extension during sporulation. Binds phosphatidylinositol 4-phosphate..
Protein Sequence MEVPSAVTLNNYVGFDSITSQINRKLIRRGFQFNVMVVGPSGSGKSTLINTLFSAHLMDSKGRLDYQAPYRQTTEIHVTSQVVRENRVQLQLNLIDTPGYGDQINNDKCWEPIIKYIRDQHSSYLRRELNSHREKRLQDTRVHCCLFFIRPTGHSLRPIDIAVLKRLTEVVNVVPVIAKSDSLTLEERAAFKQQIREEFVKHDINLYPYDSDDADEEEINLNAAVRNLIPFAVVGSEKAIIVDGRPIRGRQNRWGVVNVDDENHCEFVFLRNFLMRTHLQDLIETTSYYHYEKFRFKQLSSLKEQSSLATRMGSPAPVYPSEPHLHTATAQ
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
306PhosphorylationLSSLKEQSSLATRMG
HHHHHHHHHHHHHCC		28.5424763107
307PhosphorylationSSLKEQSSLATRMGS
HHHHHHHHHHHHCCC		23.0124763107
314PhosphorylationSLATRMGSPAPVYPS
HHHHHCCCCCCCCCC		14.4628889911
319PhosphorylationMGSPAPVYPSEPHLH
CCCCCCCCCCCCCCC		10.4428889911
321PhosphorylationSPAPVYPSEPHLHTA
CCCCCCCCCCCCCCC		46.1821712547
329PhosphorylationEPHLHTATAQ-----
CCCCCCCCCC-----		27.0925720772
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of SPN2_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of SPN2_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of SPN2_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SPN1_SCHPOspn1physical
15385632
SPN4_SCHPOspn4physical
15385632
SPN2_SCHPOspn2physical
15385632
SPN7_SCHPOspn7physical
20123972
MEU14_SCHPOmeu14genetic
20123972
HPC2_SCHPOhip4genetic
18818364
2AD1_SCHPOpar1genetic
18818364
LUB1_SCHPOlub1genetic
22681890
TUP11_SCHPOtup11genetic
22681890
CTBL1_SCHPOSPAC1952.06cgenetic
22681890
CLR4_SCHPOclr4genetic
22681890
RAF1_SCHPOraf1genetic
22681890
TOM70_SCHPOtom70genetic
22681890
YAM5_SCHPOmso1genetic
22681890
FFT3_SCHPOfft3genetic
22681890
YA99_SCHPOSPAC13G6.09genetic
22681890
TBA2_SCHPOatb2genetic
22681890
SPT20_SCHPOspt20physical
25015293
SPT20_SCHPOspt20genetic
25015293
SPN4_SCHPOspn4physical
26771498
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of SPN2_SCHPO

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Related Literatures of Post-Translational Modification

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