APE1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: APE1_SCHPO
• UniProt AC: Q9USX1
• Protein Name: Aminopeptidase 1
• Gene Name: ape1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 882
• Protein Sequence: MQVTIPKSTSKEDDKNRNLLPKNVKPIHYDLSLYPDLETFTYGGKVVVTLDVLEDSNSITLHGINLRILTAALEWGSQTVWASEVSYGDERIVLQFPSTVPANSVAVLTLPFTARISSGMEGFYRSSYVDSDGNTKYLATTQMEPTSARRAFPCWDEPALKATFTIDITAKENYTILSNMNAVEETVKDGLKTARFAETCRMSTYLLAWIVAELEYVEYFTPGKHCPRLPVRVYTTPGFSEQGKFAAELGAKTLDFFSGVFGEPYPLPKCDMVAIPDFEAGAMENWGLVTYRLAAILVSEDSAATVIERVAEVVQHELAHQWFGNLVTMQFWDGLWLNEGFATWMSWFSCNHFYPEWKVWESYVTDNLQSALSLDALRSSHPIEVPIMHDYEINQIFDAISYSKGSCVIRMVSKYVGEDTFIKGIQKYISKHRYGNTVTEDLWAALSAESGQDISSTMHNWTKKTGYPVLSVSETNDGELLIEQHRFLSTGDVKPEEDTVIYWAPLKLKTMKDGKAVVDEKAVLSDRSKKIKVDKEALESYKLNSEQSGIYRVNYSADHLKKLSQIAVEKPDYLSVEDRAGLIADVASLSRAGYGKVSSTLDLIKTWKDEPNFVVFAEMLARLNGIKSTLRFESSDIIAAMKKLVLEVSATKAHSLGWEFKANDDHIIRQFKSTVYNYAGLFGDDKVVKDALSKFDAYASGNKSAINDNLRSAVFNIAIRYGGAKSWDQLLEIYTKTNDPYVRNSCLRAFGVTEDEKYIQKTLDLTLDPIVKEQDIYLILVTLSTHKNGVLAMWKFATSNWDKLLSRLPVAGTMRGYVVRFVTSGFTHASAIDKIKEFFADKDTKLYERALQQSLDTISANSSFIDKSLDDITRWLKENRYM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
599	Phosphorylation	AGYGKVSSTLDLIKT CCCCCCHHHHHHHHH	35.66	21712547
673	Phosphorylation	HIIRQFKSTVYNYAG HHHHHHHHHHHHHHH	25.13	25720772
674	Phosphorylation	IIRQFKSTVYNYAGL HHHHHHHHHHHHHHH	27.83	25720772
704	Phosphorylation	AYASGNKSAINDNLR HHHCCCHHHHCHHHH	38.08	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of APE1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of APE1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of APE1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PRZ1_SCHPO	prz1	genetic	22496451
YN8B_SCHPO	SPBP35G2.11c	physical	26365378
LKHA4_SCHPO	SPCC1322.05c	physical	26365378

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.