PPZ_SCHPO - dbPTM
PPZ_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PPZ_SCHPO
UniProt AC P78968
Protein Name Serine/threonine-protein phosphatase PP-Z
Gene Name pzh1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 515
Subcellular Localization Cytoplasm . Nucleus
nuclear rim.
Protein Description
Protein Sequence MGQGSSKHADSKLDSYPSFSRSDTQGSIKSLKSLKTVLGKGKDSNHDRRTSTDTTHSRHRYPETPPSLPPPPSPGILATSPAVLQKHQQEDSGNSSQSPTSPHPSNQPAMLSPSTAASQHHHHHSSSSSYAVSPTSPTSPTSSGPIGSNFDSASEHNGPVYPQDQQGPVIIPNSAISSTDPDDPETVVSLNVDEMIQRLIHVGYSRKSSKSVCLKNAEITSICMAVREIFLSQPTLLELTPPVKIVGDVHGQYSDLIRLFEMCGFPPSSNYLFLGDYVDRGKQSLETILLLFLYKIRYPENFFLLRGNHECANITRVYGFYDECKRRCNIKIWKTFINTFNCLPIASVVAGKIFCVHGGLSPSLSHMDDIREIPRPTDVPDYGLLNDLLWSDPADTENDWEDNERGVSFVFNKNVIRQFLAKHDFDLICRAHMVVEDGYEFFNDRTLCTVFSAPNYCGEFDNWGAVMSVNSELLCSFELIKPLDQAAIRRELKKSKRSGMAIYQSPPAEQVTQSV
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
11PhosphorylationGSSKHADSKLDSYPS
CCCCCCCCCHHCCCC		35.5821712547
15PhosphorylationHADSKLDSYPSFSRS
CCCCCHHCCCCCCCC		49.7521712547
16PhosphorylationADSKLDSYPSFSRSD
CCCCHHCCCCCCCCC		11.5421712547
18PhosphorylationSKLDSYPSFSRSDTQ
CCHHCCCCCCCCCCC		27.8528889911
20PhosphorylationLDSYPSFSRSDTQGS
HHCCCCCCCCCCCCC		34.9028889911
22PhosphorylationSYPSFSRSDTQGSIK
CCCCCCCCCCCCCHH		43.7621712547
24PhosphorylationPSFSRSDTQGSIKSL
CCCCCCCCCCCHHHH		35.7625720772
27PhosphorylationSRSDTQGSIKSLKSL
CCCCCCCCHHHHHHH		19.6129996109
30PhosphorylationDTQGSIKSLKSLKTV
CCCCCHHHHHHHHHH		39.0829996109
33PhosphorylationGSIKSLKSLKTVLGK
CCHHHHHHHHHHHCC		40.1524763107
36PhosphorylationKSLKSLKTVLGKGKD
HHHHHHHHHHCCCCC		26.6824763107
64PhosphorylationSRHRYPETPPSLPPP
CCCCCCCCCCCCCCC		35.6829996109
67PhosphorylationRYPETPPSLPPPPSP
CCCCCCCCCCCCCCC		55.5029996109
73PhosphorylationPSLPPPPSPGILATS
CCCCCCCCCCEECCC		41.3429996109
79PhosphorylationPSPGILATSPAVLQK
CCCCEECCCHHHHHH		31.6229996109
80PhosphorylationSPGILATSPAVLQKH
CCCEECCCHHHHHHH		12.7829996109
503PhosphorylationKRSGMAIYQSPPAEQ
CCCCCCCCCCCCHHH		8.0621712547
505PhosphorylationSGMAIYQSPPAEQVT
CCCCCCCCCCHHHHC		18.8428889911
512PhosphorylationSPPAEQVTQSV----
CCCHHHHCCCC----		18.1529996109
514PhosphorylationPAEQVTQSV------
CHHHHCCCC------		22.0428889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PPZ_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PPZ_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PPZ_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SPM1_SCHPOpmk1genetic
9762918
RIK1_SCHPOrik1genetic
22681890
DHE4_SCHPOgdh1genetic
22681890
NSE6_SCHPOnse6genetic
22681890
YG58_SCHPOSPBC56F2.08cgenetic
22681890
NU132_SCHPOnup132genetic
22681890
YA33_SCHPOSPAC18B11.03cgenetic
22681890
RAF2_SCHPOraf2genetic
22681890
RNC1_SCHPOrnc1genetic
22681890
MEX67_SCHPOmex67genetic
22681890
APT_SCHPOapt1genetic
22681890
MGR2_SCHPOmgr2genetic
22681890
YF69_SCHPOSPAC23C4.09cgenetic
22681890
VIP1_SCHPOasp1genetic
22681890
YKTB_SCHPOSPAPB1E7.11cgenetic
22681890
RPA12_SCHPOrpa12genetic
22681890
CLR4_SCHPOclr4genetic
22681890
CHP1_SCHPOchp1genetic
22681890
HRQ1_SCHPOhrq1genetic
22681890
MET10_SCHPOSPCC584.01cgenetic
22681890
GCN5_SCHPOgcn5genetic
22681890
SWD1_SCHPOswd1genetic
22681890
GIT3_SCHPOgit3genetic
22681890
DCTD_SCHPOdcd1genetic
22681890
CSN1_SCHPOcsn1genetic
22681890
YBPC_SCHPOSPBC16H5.12cgenetic
22681890
FCF2_SCHPOfcf2genetic
22681890
DSC4_SCHPOdsc4genetic
22681890
ASH2_SCHPOash2genetic
22681890
RAD57_SCHPOrad57genetic
22681890
GPA2_SCHPOgpa2genetic
22681890
YOOH_SCHPOSPBC887.17genetic
22681890
AROG_SCHPOSPAP8A3.07cgenetic
22681890
RM39_SCHPOmrpl39genetic
22681890
ABC2_SCHPOabc2genetic
22681890
RAF1_SCHPOraf1genetic
22681890
YQ9H_SCHPOSPCC18.17cgenetic
22681890
MTG1_SCHPOmtg1genetic
22681890
GMA12_SCHPOgma12genetic
22681890
PTPA1_SCHPOypa1genetic
22681890
CTK3_SCHPOlsg1genetic
22681890
ASK1_SCHPOask1genetic
22681890
ALM1_SCHPOalm1genetic
22681890
YHC3_SCHPOyap18genetic
22681890
FFT3_SCHPOfft3genetic
22681890
TRM6_SCHPOgcd10genetic
22681890
DAD2_SCHPOdad2genetic
22681890
MU123_SCHPOmug123genetic
22681890
H2AZ_SCHPOpht1genetic
22681890
MID1_SCHPOmid1genetic
22681890
QCR6_SCHPOqcr6genetic
22681890
MU154_SCHPOmug154genetic
22681890
RL19B_SCHPOrpl1902genetic
22681890
RL21B_SCHPOrpl2102genetic
22681890
PRZ1_SCHPOprz1genetic
22681890
MCL1_SCHPOmcl1genetic
22681890
EHS1_SCHPOyam8genetic
22681890
RL7B_SCHPOrpl702genetic
22681890
RGA8_SCHPOrga8genetic
22681890
TCG1_SCHPOtcg1genetic
22681890
RS4A_SCHPOrps401genetic
22681890
TYSY_SCHPOhal3physical
23962284
SIS2_YEASTSIS2physical
23962284
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PPZ_SCHPO

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-18; SER-505 AND SER-514,AND MASS SPECTROMETRY.

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