YBPC_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YBPC_SCHPO
• UniProt AC: O42947
• Protein Name: Uncharacterized protein C16H5.12c
• Gene Name: SPBC16H5.12c
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 737
• Protein Sequence: MSVDTAKSDIQAEPSTGTLENKSSKTYSDSENNSTLDVSAQVLTLDNKSRILCIADVRGELSLINSLVEETNASCVIHTGDFGFFERSSLPSISERTLRHIVQFSPLIKKLPRSKNFDYYPSNPIGDLKNSIASHPDCLLSELPQFLSQEKKFSVPVYVVWGACEDVHVLEKFRSGEYSIPNLNIVDELHSYLLQIGDMKIRLLGLGGPYVPFKLFDNGDGKGTIAGGQGTMWTTILQMGELIETAKSLLDREEARIFITHHPIGREGVLSQLATACQADLTLSAGLHFRYGASYNEFCVNHSPEHYLQKLSAARAQFMEVYDTVKAEVEKMVTPEQHHLINNVVRLVSRMPDATNSYAMNNMLPGTAFKNLWNFNLLDASFGWTVFVVENGHVQVESKSHGFNLGYRRMASRRNENYASHIPRSTSENTGTYYYANNRLVESQAQFTKNREATATPTEEEQIEGYDQEHTDELGMSRANTTEESAETHEVIEEKSGPPAAEEEPISGVAEKPSPNEEEQPAIGGKEEVDVEEVTKGTGNLELGETTTEVTILEQENAANVTRSQAQEGRRTDMQKGNDREFRQYSGEQRYERCGFHITPCNSEEEARSYFKDGTDSLITNIQIRTSLNRYKSPQAPQNVNPTNYAYVFVENQNAVSKALGSIKVPEGVRVNIMRDDSYYRQNRGWYRNNRMEGHGTGMRTNRGRGRGGRMNRMQHPRPLQSGGSVNKQSAEPTTHG

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSVDTAKSD ------CCCCCCHHH	28.80	24763107
5	Phosphorylation	---MSVDTAKSDIQA ---CCCCCCHHHCCC	33.55	29996109
8	Phosphorylation	MSVDTAKSDIQAEPS CCCCCCHHHCCCCCC	37.17	29996109
15	Phosphorylation	SDIQAEPSTGTLENK HHCCCCCCCCCCCCC	30.86	29996109
16	Phosphorylation	DIQAEPSTGTLENKS HCCCCCCCCCCCCCC	44.92	24763107
26	Phosphorylation	LENKSSKTYSDSENN CCCCCCCCCCCCCCC	30.15	24763107
27	Phosphorylation	ENKSSKTYSDSENNS CCCCCCCCCCCCCCC	17.76	25720772
28	Phosphorylation	NKSSKTYSDSENNST CCCCCCCCCCCCCCE	39.63	25720772
30	Phosphorylation	SSKTYSDSENNSTLD CCCCCCCCCCCCEEE	35.96	29996109
34	Phosphorylation	YSDSENNSTLDVSAQ CCCCCCCCEEEEEEE	41.76	25720772
35	Phosphorylation	SDSENNSTLDVSAQV CCCCCCCEEEEEEEE	29.15	25720772
105	Phosphorylation	LRHIVQFSPLIKKLP HHHHHHHHHHHHHCC	11.16	21712547
426	Phosphorylation	ASHIPRSTSENTGTY HHCCCCCCCCCCCCE	41.14	25720772
427	Phosphorylation	SHIPRSTSENTGTYY HCCCCCCCCCCCCEE	30.05	25720772
454	Phosphorylation	FTKNREATATPTEEE HHCCCCCCCCCCHHH	26.72	25720772
456	Phosphorylation	KNREATATPTEEEQI CCCCCCCCCCHHHHH	26.79	28889911
458	Phosphorylation	REATATPTEEEQIEG CCCCCCCCHHHHHCC	52.23	28889911
466	Phosphorylation	EEEQIEGYDQEHTDE HHHHHCCCCHHHHHH	11.15	29996109
471	Phosphorylation	EGYDQEHTDELGMSR CCCCHHHHHHHCCCC	30.34	29996109
477	Phosphorylation	HTDELGMSRANTTEE HHHHHCCCCCCCCHH	26.83	29996109
481	Phosphorylation	LGMSRANTTEESAET HCCCCCCCCHHHHHH	34.30	29996109
482	Phosphorylation	GMSRANTTEESAETH CCCCCCCCHHHHHHH	37.25	25720772
485	Phosphorylation	RANTTEESAETHEVI CCCCCHHHHHHHHHH	25.77	25720772
514	Phosphorylation	SGVAEKPSPNEEEQP CCCCCCCCCCCCCCC	51.96	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YBPC_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YBPC_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YBPC_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ATF21_SCHPO	atf21	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-456 AND THR-458, ANDMASS SPECTROMETRY.
PubMed: 18257517