PPK29_SCHPO - dbPTM
PPK29_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID PPK29_SCHPO
UniProt AC Q9USS2
Protein Name Serine/threonine-protein kinase ppk29
Gene Name ppk29
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 872
Subcellular Localization Cytoplasm .
Protein Description
Protein Sequence MSVASFLTGEKLLAGSKFVIGKYNVTIEKYIAEGGFSHVYLVQTNSKTDGSPITAVLKRMYSPDENALRFVKTEIETMELLKSNPHVVSYIDSCIFPLEKAGVNTGFEILLLMEYCAGGGLIDFMNQRLQTRLSEHEVLKIISDIVQGVASLHYLRPPLIHRDLKVENVLLSFNTFKLCDFGSVTEPMHAAENSSEIQALEKSINTFTTYQYRAPEMINLYSGLGIDEKSDMWALGVLLYKLCYYTTPFETQGPNAILTASYSFPPFPPYSHSLKNVIIALLQPNPCLRPNIFQLMCEICRLRGTALPFRDIYSGRESSFYDLHNRKIMSLLRQTTTTPFAGNQVMPTPQVQGSRPPPPPPMPAPIYNVPNVPTVPTVSPNPFLQPTFSGTSQASAHPSIHSQSATFNNTQDVNRQSVSSPKVVSSSSVTGSGASGRKVYTPQSKNPFPISQGVTGTSSKFSASEVTEDNGSPNAGLDADNVDVEEVVNQRYPDLNELESQLTSHTNITTSSHHNPREQEIAKLADDAFASFRQTAGTSTANSTHTTGTQDISAFDTNFSEGVGSVRSSFDFPDRPVSRRPSSTSRSSVKITGPSSPNARSMAYEQHSFNLDDLSNTNFGSNNSLRHAKSFSKYYSPSHKDSNKTSRNTSKEGLPSSPTMLYRTTSNTRGDYIVQRTQQSANPLTNIEPQDMSNLSTDINASDVVADSTNSILYPTSTASSVANTIASDVDDFGTFNGLQRTVSLHSERASLDKKRPSFHDKNPYFKFSPSKYVDEGLEGESELRERVRSYANRSSSSFHNPDLTDTEIQETSFNNDLRPVASIQSAETSRSVSDRPANFPEELNDTLFEQKYPGIVDYEEPNSNAEKNVNI
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
2Phosphorylation------MSVASFLTG
------CCHHHHHCC		26.7921712547
5Phosphorylation---MSVASFLTGEKL
---CCHHHHHCCCCC		20.7321712547
8PhosphorylationMSVASFLTGEKLLAG
CCHHHHHCCCCCCCC		41.0828889911
425PhosphorylationVSSPKVVSSSSVTGS
CCCCEEEECCCCCCC		27.7321712547
426PhosphorylationSSPKVVSSSSVTGSG
CCCEEEECCCCCCCC		18.2821712547
427PhosphorylationSPKVVSSSSVTGSGA
CCEEEECCCCCCCCC		22.7121712547
428PhosphorylationPKVVSSSSVTGSGAS
CEEEECCCCCCCCCC		26.1625720772
430PhosphorylationVVSSSSVTGSGASGR
EEECCCCCCCCCCCC		27.8125720772
432PhosphorylationSSSSVTGSGASGRKV
ECCCCCCCCCCCCEE		23.0921712547
435PhosphorylationSVTGSGASGRKVYTP
CCCCCCCCCCEEECC		42.5324763107
451PhosphorylationSKNPFPISQGVTGTS
CCCCCCCCCCCCCCC		22.5625720772
455PhosphorylationFPISQGVTGTSSKFS
CCCCCCCCCCCCCCC		41.3824763107
457PhosphorylationISQGVTGTSSKFSAS
CCCCCCCCCCCCCHH		22.0629996109
458PhosphorylationSQGVTGTSSKFSASE
CCCCCCCCCCCCHHH		32.6428889911
459PhosphorylationQGVTGTSSKFSASEV
CCCCCCCCCCCHHHC		37.2429996109
467PhosphorylationKFSASEVTEDNGSPN
CCCHHHCCCCCCCCC		33.3025720772
472PhosphorylationEVTEDNGSPNAGLDA
HCCCCCCCCCCCCCC		22.6428889911
500PhosphorylationPDLNELESQLTSHTN
CCHHHHHHHHHHCCC		43.0129996109
503PhosphorylationNELESQLTSHTNITT
HHHHHHHHHCCCCCC		15.7229996109
504PhosphorylationELESQLTSHTNITTS
HHHHHHHHCCCCCCC		36.5929996109
506PhosphorylationESQLTSHTNITTSSH
HHHHHHCCCCCCCCC		28.2529996109
509PhosphorylationLTSHTNITTSSHHNP
HHHCCCCCCCCCCCH		23.7729996109
512PhosphorylationHTNITTSSHHNPREQ
CCCCCCCCCCCHHHH		27.0329996109
538PhosphorylationSFRQTAGTSTANSTH
HHHHHCCCCCCCCCC		22.0525720772
539PhosphorylationFRQTAGTSTANSTHT
HHHHCCCCCCCCCCC		25.3025720772
544PhosphorylationGTSTANSTHTTGTQD
CCCCCCCCCCCCCCC		24.0527738172
568PhosphorylationEGVGSVRSSFDFPDR
CCCCCCCCCCCCCCC		32.9529996109
569PhosphorylationGVGSVRSSFDFPDRP
CCCCCCCCCCCCCCC		20.4728889911
578PhosphorylationDFPDRPVSRRPSSTS
CCCCCCCCCCCCCCC		25.8428889911
582PhosphorylationRPVSRRPSSTSRSSV
CCCCCCCCCCCCCCC		44.4225720772
583PhosphorylationPVSRRPSSTSRSSVK
CCCCCCCCCCCCCCE		32.8425720772
584PhosphorylationVSRRPSSTSRSSVKI
CCCCCCCCCCCCCEE		32.2825720772
585PhosphorylationSRRPSSTSRSSVKIT
CCCCCCCCCCCCEEC		31.9225720772
587PhosphorylationRPSSTSRSSVKITGP
CCCCCCCCCCEECCC		38.9725720772
588PhosphorylationPSSTSRSSVKITGPS
CCCCCCCCCEECCCC		26.7325720772
592PhosphorylationSRSSVKITGPSSPNA
CCCCCEECCCCCCCH		37.0021712547
595PhosphorylationSVKITGPSSPNARSM
CCEECCCCCCCHHHH		60.8325720772
596PhosphorylationVKITGPSSPNARSMA
CEECCCCCCCHHHHH		25.8828889911
601PhosphorylationPSSPNARSMAYEQHS
CCCCCHHHHHHHHHC		12.8321712547
604PhosphorylationPNARSMAYEQHSFNL
CCHHHHHHHHHCCCH		13.8921712547
630PhosphorylationNSLRHAKSFSKYYSP
CHHHHHHHHHHHCCC		35.2225720772
634PhosphorylationHAKSFSKYYSPSHKD
HHHHHHHHCCCCCCC		14.1525720772
635PhosphorylationAKSFSKYYSPSHKDS
HHHHHHHCCCCCCCC		20.1725720772
636PhosphorylationKSFSKYYSPSHKDSN
HHHHHHCCCCCCCCC		19.4821712547
638PhosphorylationFSKYYSPSHKDSNKT
HHHHCCCCCCCCCCC		36.9124763107
642PhosphorylationYSPSHKDSNKTSRNT
CCCCCCCCCCCCCCC		45.0621712547
650PhosphorylationNKTSRNTSKEGLPSS
CCCCCCCCCCCCCCC		32.0525720772
656PhosphorylationTSKEGLPSSPTMLYR
CCCCCCCCCCCEEEE		54.7329996109
657PhosphorylationSKEGLPSSPTMLYRT
CCCCCCCCCCEEEEC		23.5828889911
659PhosphorylationEGLPSSPTMLYRTTS
CCCCCCCCEEEECCC		23.0429996109
664PhosphorylationSPTMLYRTTSNTRGD
CCCEEEECCCCCCCC		22.4829996109
666PhosphorylationTMLYRTTSNTRGDYI
CEEEECCCCCCCCEE		35.2725720772
742PhosphorylationTFNGLQRTVSLHSER
CCCCHHHCHHHHHHC		11.0725720772
744PhosphorylationNGLQRTVSLHSERAS
CCHHHCHHHHHHCCC		21.5425720772
747PhosphorylationQRTVSLHSERASLDK
HHCHHHHHHCCCCCC		33.7928889911
751PhosphorylationSLHSERASLDKKRPS
HHHHHCCCCCCCCCC		43.2425720772
765PhosphorylationSFHDKNPYFKFSPSK
CCCCCCCCCCCCHHH		28.8821712547
769PhosphorylationKNPYFKFSPSKYVDE
CCCCCCCCHHHHCCC		28.9324763107
771PhosphorylationPYFKFSPSKYVDEGL
CCCCCCHHHHCCCCC		35.1121712547
773PhosphorylationFKFSPSKYVDEGLEG
CCCCHHHHCCCCCCC		19.9229996109
795PhosphorylationVRSYANRSSSSFHNP
HHHHHHCCCCCCCCC		34.0929996109
796PhosphorylationRSYANRSSSSFHNPD
HHHHHCCCCCCCCCC		27.1129996109
797PhosphorylationSYANRSSSSFHNPDL
HHHHCCCCCCCCCCC		37.9729996109
805PhosphorylationSFHNPDLTDTEIQET
CCCCCCCCCCHHHHC		48.5329996109
807PhosphorylationHNPDLTDTEIQETSF
CCCCCCCCHHHHCCC		29.7429996109
812PhosphorylationTDTEIQETSFNNDLR
CCCHHHHCCCCCCCC		23.4229996109
813PhosphorylationDTEIQETSFNNDLRP
CCHHHHCCCCCCCCC		25.8129996109
823PhosphorylationNDLRPVASIQSAETS
CCCCCCEEEECCCCC		22.7627738172
832PhosphorylationQSAETSRSVSDRPAN
ECCCCCCCCCCCCCC		26.2429996109
834PhosphorylationAETSRSVSDRPANFP
CCCCCCCCCCCCCCC		29.2029996109
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of PPK29_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of PPK29_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of PPK29_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
YCRE_SCHPOtrs130genetic
22681890
YDO6_SCHPOSPAC15A10.06genetic
22681890
6PGL_SCHPOSPCC16C4.10genetic
22681890
YOS6_SCHPOSPBC21C3.06genetic
22681890
ARP8_SCHPOarp8genetic
22681890
SCS7_SCHPOscs7genetic
22681890
YBLC_SCHPOSPBC106.12cgenetic
22681890
HUS1_SCHPOhus1genetic
22681890
HSP71_SCHPOssa1genetic
22681890
PPK16_SCHPOppk16genetic
22681890
PPK38_SCHPOppk38genetic
22681890
TOM70_SCHPOtom70genetic
22681890
DAD2_SCHPOdad2genetic
22681890
EMC1_SCHPOemc1genetic
22681890
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of PPK29_SCHPO

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Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-472; SER-596 ANDSER-657, AND MASS SPECTROMETRY.

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