RGA3_SCHPO - dbPTM
RGA3_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID RGA3_SCHPO
UniProt AC O14014
Protein Name Probable Rho-type GTPase-activating protein 3
Gene Name rga3
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 969
Subcellular Localization Cell septum . Cell poles and septum.
Protein Description GTPase-activating protein for Rho-type proteins..
Protein Sequence MIFRKSISKSPSSKGSTVCFRCGQAFQRRETPISFGGHMWHKDCFCCTKCDKGLEHSDQMLVQTSDGRPVCSSCAHTCTACRMRIKDYALMSGYDSYHRECFRCHDCRKQIIDSNFKRDNRTIFCNDCKQVRHPSRSSDESADYHNFEVDVTIKPTETKSSVESNKSLSIEIMSPQKPPLSPFGGSRDRLVSETPTNMSQAEGGNVPNDGQDSNLASNSADSLLPSAKNRSFSSFTSFESPMKYDDSFFPISPSISPLQKVNKQQQIESPTATFPLSKNTWKNRFHTFHKQSFTPVNDSSSSDSLKPTINEEALDDFAGSASPYKTMSLTDRAEPIVMNGHMRSLHNATSPFRPFSPSYRSSDTHSPRTRSPNVQTHKKTSSQPSDLSSFAQLLSPPQVLSPKPNGGGHKSFRHSHSLSETSQQTLVPSLGSNGEYHLPTNDHSSTPAQSERDSDVEELREQLENLTALTKKLSERLSSSTFDNSKFIRTEDKDTVRSAKLEICEKFFSFADVTDDPTLKDPKHQDLVAAANAYMAMLRESYGTEINNLLERRNELLDDYNNVQKILNESLEASVHLNTKNLELADLNNNLVKQIQHRVPPENQSNLEHTITTSSKNTTSSINPLTAVSSNSGQSSGRPGPLSPNLNVTTRIDIKGKKGSMHLQPRDVNRKVPFKSMHTKSKSADPVVGNEDRTQCDHVFHVNAIFKPSRCYICSESVWGSELRCFHCSISCHSRCLKRLFAESEHEKTMSETVSENSKWMPEMPTRMPPPGPSPTMFGRSLENQLKIEGSVLPQVIAMCVSCVDAHGLEVEGIYRISGSASQVRVLVDEFENGSIRMEHLTSDLFACTSVLKTYLHRLPEPVIPGTQYEELLEAEKIEKEEEKIERVVEVMKTLHPAHLSVFRFLIAHLGRVCKHAEKNLMNSKNVSTVFAPTLMRDKVNRFDLQHATKKSTALQFMLDNVDKILHNL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
167PhosphorylationSSVESNKSLSIEIMS
CHHHCCCCEEEEEEC
31.4429996109
169PhosphorylationVESNKSLSIEIMSPQ
HHCCCCEEEEEECCC
25.8529996109
174PhosphorylationSLSIEIMSPQKPPLS
CEEEEEECCCCCCCC
29.8229996109
181PhosphorylationSPQKPPLSPFGGSRD
CCCCCCCCCCCCCCC
24.7729996109
186PhosphorylationPLSPFGGSRDRLVSE
CCCCCCCCCCCCCCC
31.2425720772
213PhosphorylationVPNDGQDSNLASNSA
CCCCCCCCCCCCCCH
26.3427738172
217PhosphorylationGQDSNLASNSADSLL
CCCCCCCCCCHHHHC
34.1927738172
231PhosphorylationLPSAKNRSFSSFTSF
CCCCCCCCCCCCCCC
38.5824763107
233PhosphorylationSAKNRSFSSFTSFES
CCCCCCCCCCCCCCC
26.2821712547
234PhosphorylationAKNRSFSSFTSFESP
CCCCCCCCCCCCCCC
30.4521712547
236PhosphorylationNRSFSSFTSFESPMK
CCCCCCCCCCCCCCC
34.1621712547
237PhosphorylationRSFSSFTSFESPMKY
CCCCCCCCCCCCCCC
25.6321712547
240PhosphorylationSSFTSFESPMKYDDS
CCCCCCCCCCCCCCC
28.4321712547
247PhosphorylationSPMKYDDSFFPISPS
CCCCCCCCCCCCCCC
26.3729996109
252PhosphorylationDDSFFPISPSISPLQ
CCCCCCCCCCCCHHH
16.9124763107
254PhosphorylationSFFPISPSISPLQKV
CCCCCCCCCCHHHHC
28.9829996109
256PhosphorylationFPISPSISPLQKVNK
CCCCCCCCHHHHCCH
24.7224763107
269PhosphorylationNKQQQIESPTATFPL
CHHHCCCCCCCCCCC
29.2228889911
271PhosphorylationQQQIESPTATFPLSK
HHCCCCCCCCCCCCC
47.8329996109
273PhosphorylationQIESPTATFPLSKNT
CCCCCCCCCCCCCCC
28.4125720772
294PhosphorylationTFHKQSFTPVNDSSS
EECCCCCCCCCCCCC
31.4125720772
320PhosphorylationALDDFAGSASPYKTM
HHHHCCCCCCCCCEE
23.3429996109
322PhosphorylationDDFAGSASPYKTMSL
HHCCCCCCCCCEECC
30.3824763107
344PhosphorylationVMNGHMRSLHNATSP
EECCCHHHCCCCCCC
26.8029996109
349PhosphorylationMRSLHNATSPFRPFS
HHHCCCCCCCCCCCC
42.1029996109
350PhosphorylationRSLHNATSPFRPFSP
HHCCCCCCCCCCCCC
21.4529996109
356PhosphorylationTSPFRPFSPSYRSSD
CCCCCCCCCCCCCCC
18.6725720772
358PhosphorylationPFRPFSPSYRSSDTH
CCCCCCCCCCCCCCC
31.7925720772
359PhosphorylationFRPFSPSYRSSDTHS
CCCCCCCCCCCCCCC
20.2125720772
369PhosphorylationSDTHSPRTRSPNVQT
CCCCCCCCCCCCCCC
38.5929996109
371PhosphorylationTHSPRTRSPNVQTHK
CCCCCCCCCCCCCCC
21.8829996109
376PhosphorylationTRSPNVQTHKKTSSQ
CCCCCCCCCCCCCCC
31.2329996109
380PhosphorylationNVQTHKKTSSQPSDL
CCCCCCCCCCCCCCH
38.1121712547
381PhosphorylationVQTHKKTSSQPSDLS
CCCCCCCCCCCCCHH
35.5425720772
382PhosphorylationQTHKKTSSQPSDLSS
CCCCCCCCCCCCHHH
51.8725720772
385PhosphorylationKKTSSQPSDLSSFAQ
CCCCCCCCCHHHHHH
43.4725720772
395PhosphorylationSSFAQLLSPPQVLSP
HHHHHHHCCCCCCCC
43.0321712547
401PhosphorylationLSPPQVLSPKPNGGG
HCCCCCCCCCCCCCC
31.8321712547
626PhosphorylationTSSINPLTAVSSNSG
CCCCCCCEEEECCCC
26.6925720772
629PhosphorylationINPLTAVSSNSGQSS
CCCCEEEECCCCCCC
22.7225720772
643PhosphorylationSGRPGPLSPNLNVTT
CCCCCCCCCCCCEEE
18.1829996109
681PhosphorylationFKSMHTKSKSADPVV
CCCCCCCCCCCCCCC
32.7625720772
683PhosphorylationSMHTKSKSADPVVGN
CCCCCCCCCCCCCCC
45.0225720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of RGA3_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of RGA3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of RGA3_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
COX19_SCHPOSPCC1672.04cgenetic
22681890
YE7A_SCHPOSPAC4A8.10genetic
22681890
MDE5_SCHPOmde5genetic
22681890
YAV5_SCHPOSPAC27F1.05cgenetic
22681890
PFD4_SCHPOSPAC227.05genetic
22681890
YF14_SCHPOSPAC9E9.04genetic
22681890
DI3L2_SCHPOdis32genetic
22681890
YHZ8_SCHPOSPBC21B10.08cgenetic
22681890
PCK1_SCHPOpck1genetic
22681890
SCE3_SCHPOsce3genetic
22681890
YDX3_SCHPOSPAC4C5.03genetic
22681890
YFY2_SCHPOSPAC9.02cgenetic
22681890
YBQ3_SCHPOSPBC115.03genetic
22681890
UFD2_SCHPOufd2genetic
22681890
YQ53_SCHPOSPCC162.03genetic
22681890
ATG18_SCHPOatg1801genetic
22681890
YI32_SCHPOSPAC1399.02genetic
22681890
YBN2_SCHPOSPBC8E4.02cgenetic
22681890
PPR2_SCHPOppr2genetic
22681890
GSK3_SCHPOgsk3genetic
22681890
MEU10_SCHPOmeu10genetic
22681890
SWC3_SCHPOswc3genetic
22681890
ATP12_SCHPOatp12genetic
22681890
UBC15_SCHPOubc15genetic
22681890
RL43B_SCHPOrpl4302genetic
22681890
SKI2_SCHPOSPCC550.03cgenetic
22681890
YKQC_SCHPOSPAC688.12cgenetic
22681890
YEAF_SCHPOSPACUNK4.15genetic
22681890
YI7F_SCHPOSPAC977.15genetic
22681890
MEU6_SCHPOmeu6genetic
22681890
PEX6_SCHPOpex6genetic
22681890
PEX5_SCHPOpex5genetic
22681890
PTR2_SCHPOptr2genetic
22681890
ATP5E_SCHPOatp15genetic
22681890
BYR3_SCHPObyr3genetic
22681890
CYSK_SCHPOcys11genetic
22681890
PDS5_SCHPOpds5genetic
22681890
YOSE_SCHPOSPBC21C3.14cgenetic
22681890
CAND1_SCHPOknd1genetic
22681890
YDHG_SCHPOSPAC6G9.16cgenetic
22681890
TOM70_SCHPOtom70genetic
22681890
BUT2_SCHPObut2genetic
22681890
YD22_SCHPOSPAC56F8.02genetic
22681890
MU123_SCHPOmug123genetic
22681890
YD3B_SCHPOSPAC13G7.11genetic
22681890
YKI7_SCHPOSPAC630.07cgenetic
22681890
CSK1_SCHPOcsk1genetic
22681890
LNP_SCHPOlnp1genetic
22681890
TEA3_SCHPOtea3physical
26771498
YGDG_SCHPOSPBC1773.16cphysical
26771498

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of RGA3_SCHPO

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Related Literatures of Post-Translational Modification

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