dbPTM

SWC3_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	SWC3_SCHPO
UniProt AC	Q10210
Protein Name	SWR1 complex subunit swc3
Gene Name	swc3
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	391
Subcellular Localization	Nucleus . Cytoplasm .
Protein Description	Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling..
Protein Sequence	MSLNGTFSHNNGLPSGEREESETPGGSTSIISSSFLLQPRASDSRPDALEGKYDKNVLARALKKSRDSCLNGALFEKFLPEENYKLSGGTVFSHVRYIDTATLCVGPLRFEDTKFYFVHYSNSPIEPFAKPNISYVNPQWNELDYRPDSQKLSPGKEKNTLDLKHCLLPSPEYKAPPAKKPEDYEASPGEPVEPLITDASLQRLKSRANEDPTIFNILKRISKGLGTPEQCMLLHNELIGPSTFPLPKRAKKPPRKRITLSINQQDKDEFFDSLINNKKEVRRHFDIVMEFSDAPDTKWIFPRESVLSHVFNTDKKKLEALSLLFHVYRPTEDRNVIDVKTEIKIRDFTPTLRSAIELLTSGTHADRLLSEKRRRMSNLEPKYYMQFHEQT

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
149	Phosphorylation	ELDYRPDSQKLSPGK CCCCCCCCCCCCCCC		24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of SWC3_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of SWC3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of SWC3_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ARP8_SCHPO	arp8	genetic	18818364
ASH2_SCHPO	ash2	genetic	18818364
ASK1_SCHPO	ask1	genetic	18818364
YO48_SCHPO	SPBC36B7.08c	genetic	18818364
RSC1_SCHPO	rsc1	genetic	18818364
POB3_SCHPO	pob3	genetic	18818364
HPC2_SCHPO	hip4	genetic	18818364
ABP1_SCHPO	cbp1	genetic	18818364
H2AZ_SCHPO	pht1	genetic	18818364
NGG1_SCHPO	ngg1	genetic	18818364
YB33_SCHPO	ebs1	genetic	18818364
ELP1_SCHPO	elp1	genetic	18818364
ELP6_SCHPO	elp6	genetic	18818364
ELP4_SCHPO	elp4	genetic	18818364
ARP6_SCHPO	arp6	genetic	18818364
MPH1L_SCHPO	mph1	genetic	22681890
SWR1_SCHPO	swr1	genetic	22681890
ERI1_SCHPO	eri1	genetic	22681890
COQ5_SCHPO	coq5	genetic	22681890
ATP10_SCHPO	atp10	genetic	22681890
ARP6_SCHPO	arp6	genetic	22681890
YAC5_SCHPO	cph1	genetic	22681890
DEP1_SCHPO	dep1	genetic	22681890
ARP8_SCHPO	arp8	genetic	22681890
SPP1_SCHPO	spf1	genetic	22681890
DAD1_SCHPO	dad1	genetic	22681890
SWD1_SCHPO	swd1	genetic	22681890
MUG80_SCHPO	mug80	genetic	22681890
POM1_SCHPO	pom1	genetic	22681890
PPR8_SCHPO	ppr8	genetic	22681890
PHD1_SCHPO	hos2	genetic	22681890
SET3_SCHPO	set3	genetic	22681890
YBPC_SCHPO	SPBC16H5.12c	genetic	22681890
MSC1_SCHPO	msc1	genetic	22681890
ASH2_SCHPO	ash2	genetic	22681890
YF19_SCHPO	atd1	genetic	22681890
NU124_SCHPO	nup124	genetic	22681890
MHF2_SCHPO	mhf2	genetic	22681890
SNT2_SCHPO	snt2	genetic	22681890
YO48_SCHPO	SPBC36B7.08c	genetic	22681890
VPS72_SCHPO	swc2	genetic	22681890
YIU1_SCHPO	saf5	genetic	22681890
TGCE3_SCHPO	SPBC14C8.15	genetic	22681890
YQ9A_SCHPO	SPCC18.10	genetic	22681890
FFT3_SCHPO	fft3	genetic	22681890
RGA3_SCHPO	rga3	genetic	22681890
DAD2_SCHPO	dad2	genetic	22681890
ARV1_SCHPO	arv1	genetic	22681890
H2AZ_SCHPO	pht1	genetic	22681890
MID1_SCHPO	mid1	genetic	22681890
SODM_SCHPO	SPAC1486.01	genetic	22681890
RF1M_SCHPO	mrf1	genetic	22681890

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of SWC3_SCHPO

Related Literatures of Post-Translational Modification