ERI1_SCHPO - dbPTM
ERI1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID ERI1_SCHPO
UniProt AC Q08I43
Protein Name 3'-5' exonuclease eri1
Gene Name eri1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 313
Subcellular Localization Cytoplasm .
Protein Description RNA exonuclease that acts as a negative regulator of RNA interference (RNAi). Acts by degrading the 3'-overhangs of double-stranded short interfering RNAs (siRNAs). Represses the accumulation of heterochromatic siRNAs leading to negative regulation of the RNAi-mediated heterochromoatin assembly. Also involved in rRNA biogenesis, trimming the 5.8S ribosomal RNA (rRNA) from a slightly longer pre-5.8S RNA in the cytoplasm..
Protein Sequence MESPVQILVWPFPCDEMNQKTPSTVEEIRIALQELGLSTNGNKEKLKRRWKFREKRLEEKRKQERYQKFSTSNENKTCLRYLLIVDVEATCEEGCGFSFENEIIELPCLLFDLIEKSIIDEFHSYVRPSMNPTLSDYCKSLTGIQQCTVDKAPIFSDVLEELFIFLRKHSNILVPSVDEIEIIEPLKSVPRTQPKNWAWACDGPWDMASFLAKQFKYDKMPIPDWIKGPFVDIRSFYKDVYRVPRTNINGMLEHWGLQFEGSEHRGIDDARNLSRIVKKMCSENVEFECNRWWMEYEKNGWIPNRSYPPYFAS
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of ERI1_SCHPO !!
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of ERI1_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of ERI1_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of ERI1_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
REB1_SCHPOreb1genetic
22681890
SWR1_SCHPOswr1genetic
22681890
YEG5_SCHPOmga2genetic
22681890
PFD5_SCHPObob1genetic
22681890
DBR1_SCHPOdbr1genetic
22681890
YIQ4_SCHPOSPAC824.04genetic
22681890
YLO2_SCHPOtma23genetic
22681890
PAB2_SCHPOpab2genetic
22681890
SWC3_SCHPOswc3genetic
22681890
PHD1_SCHPOhos2genetic
22681890
SET3_SCHPOset3genetic
22681890
MSC1_SCHPOmsc1genetic
22681890
ASH2_SCHPOash2genetic
22681890
SNT2_SCHPOsnt2genetic
22681890
YCO6_SCHPOnap1genetic
22681890
TOM70_SCHPOtom70genetic
22681890
YQ9A_SCHPOSPCC18.10genetic
22681890
FFT3_SCHPOfft3genetic
22681890
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of ERI1_SCHPO

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Related Literatures of Post-Translational Modification

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