CAND1_SCHPO - dbPTM
CAND1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CAND1_SCHPO
UniProt AC Q9P3A8
Protein Name Cullin-associated NEDD8-dissociated protein 1
Gene Name knd1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 1220
Subcellular Localization Nucleus .
Protein Description Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor (Probable)..
Protein Sequence MEEGILLKKYVESSDKDIRYMALSDLAARLNDANHLKNLKLESFPDTLDVLLQALSDASPEVQQEAVRCVAIISSKIPQDKLKSTVENLLSGVAGKKSKNYLSALSLLLSNSNVQPFVNKFYTSTVFPSFLQILKQYNVAQEEFFAILCVVCDSLEIYHSNLSTLLPNNFELCIDVFQKCTTQCQRELIIKKACYLLSDVSLYGPRFAYKYIIEVLDRGLGPSTQMSEVNISIKLLNEILLSSKKEKDSSTSFISTAVADYTNKILSLLKKEEAPDELTQKLLEVLGLLLEYQQVNILKIWPELHGLLISKISYDPNLISDTNDEDDIADFLEEMSDYSSIYEDEEDVSWIVRRESLKVVLSVILSRLEYLPIVLQALGTSVVSKLNDREESVCLISIEVLKQAFLHVPRWIEVYATSNDRKRRYEGLPSDRSAISDTSIYLVSVIGKHVSKLSDKTPLSIVSELLNLVTVIFSSRDLGVQSEFSNLSSIIYRFPDFSTLDIKIKLNLVRLISAIISCGCEEIENMESKMSTILSLAVQNNYPQLSYEALITELSFCKYIHKKQPTNVSTDFSTMIDSSLQLLESKISDLKVRLALIDLVSQYVILFYEPDFDSIFLRRVLIILCKKLQEEPTRSAAARALCDIFMSVTDITKIENGTKIYEEILQDCCRHIDKSGNEFTTAYLELLEVLLKVGQKYLAESLLEHILGLLIETLKRNTENTVAILKCLLIIPLSILLKSKNLLIDTIISHLQSSTIHLNEESVCLLSRIIAVISKEEDLELIINSFTCAQKPVEEMVTLALIAAQLICIFQSKAIVTSLNKSFMSPKSEVRIKVFTTLIFGQLDYGKLTLPANEYFDTIASNLNSPNADVMKAAAIALGSLTSQSEKFIKELCALYVSDAYDKELLLISFLTFLKKSKIDYETADKIWDILSKDIENIKDFSTSPFRTLLSECLGLLICNESSSLYYKLELLSSSEASNHMLLSLSVFRFSLTLDCPKLKAYEKQFFEKAYKLFQNPDLEVSQETLQVIISVIKNRRSCIADVYNELLQGLISKSSVDSSNVHVVQMGPFQHVVDNSINQRQLVFETLYSLLDIPESLNHLTHFLQVSVMGLEDEHYIKLVSLSILEKLVDCSPSIIDEQVDTILEALRKIIELRKTEKTLKTDSDNILDLVRSALRVLFTMKLKCDNPVISEFESQVQKGPYSLEYEGIKNEIKTTIKT
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster

Oops, there are no PTM records of CAND1_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CAND1_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CAND1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CAND1_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
DDB1_SCHPOddb1genetic
18818364
SCS7_SCHPOscs7genetic
18818364
CSN7_SCHPOcsn71genetic
18818364
PPK15_SCHPOppk15genetic
18818364
COPE_SCHPOsec28genetic
18818364
YB3C_SCHPOcay1genetic
18818364
VHT1_SCHPOvht1genetic
22681890
PT191_SCHPOSPBC16A3.16genetic
22681890
YE88_SCHPOSPAC9G1.08cgenetic
22681890
YDPH_SCHPOSPAC29A4.17cgenetic
22681890
TR852_SCHPOtrs8502genetic
22681890
YJC2_SCHPOSPCC736.02genetic
22681890
IMA3_SCHPOSPCC550.11genetic
22681890
FRP2_SCHPOfrp2genetic
22681890
SIF2_SCHPOsif2genetic
22681890
MFS2_SCHPOmfs2genetic
22681890
TYW2_SCHPOtrm12genetic
22681890
YQ72_SCHPOSPCC1442.02genetic
22681890
PGT1_SCHPOpgt1genetic
22681890
TRM10_SCHPOtrm10genetic
22681890
IST1_SCHPOist1genetic
22681890
FTA6_SCHPOfta6genetic
22681890
SWD1_SCHPOswd1genetic
22681890
YO45_SCHPOSPBC36B7.05cgenetic
22681890
PPR8_SCHPOppr8genetic
22681890
ECM29_SCHPOecm29genetic
22681890
ASH2_SCHPOash2genetic
22681890
RRG9_SCHPOrrg9genetic
22681890
PSL1_SCHPOpsl1genetic
22681890
SOL1_SCHPOsol1genetic
22681890
MTNB_SCHPOSPAC20H4.05cgenetic
22681890
MUG20_SCHPOmug20genetic
22681890
NDH1_SCHPOnde2genetic
22681890
AROG_SCHPOSPAP8A3.07cgenetic
22681890
YIDH_SCHPOSPAC227.17cgenetic
22681890
ADN2_SCHPOadn2genetic
22681890
YGI7_SCHPOhpz1genetic
22681890
SET1_SCHPOset1genetic
22681890
YJKA_SCHPOSPCC18B5.10cgenetic
22681890
PPK16_SCHPOppk16genetic
22681890
SGT2_SCHPOSPAC1142.02cgenetic
22681890
TOM70_SCHPOtom70genetic
22681890
RGA3_SCHPOrga3genetic
22681890
ALAT_SCHPOSPBC582.08genetic
22681890
YAS5_SCHPOmms1genetic
22681890
IMA2_SCHPOimp1genetic
22681890
FHP_SCHPOSPAC869.02cgenetic
22681890
BGLS_SCHPOSPBC1683.04genetic
22681890
GYP51_SCHPOgyp51genetic
22681890

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CAND1_SCHPO

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Related Literatures of Post-Translational Modification

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