PGT1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: PGT1_SCHPO
• UniProt AC: O14031
• Protein Name: Glutathione transporter 1
• Gene Name: pgt1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 851
• Subcellular Localization: Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
• Protein Description: High-affinity glutathione transporter which plays a role in scavenging glutathione from the extracellular environment for the maintenance of sulfur homeostasis..
• Protein Sequence: MTARNSASIPTSIRKTSENEVSGDETPAGVGNLSTKTASKTSLTFRQSSSDESTSSYSGNHHNINIQHHPNRPFRTNSSSFSPNDYSISESPSKSKKDGVHVSAVQLDNETDSEVESEVEELERELEAIEDSVYPEVRAAVNPTDDVNLPVNTWRTWVLTTIFVIVFAAVNQFFSLRYPALSISFIVAQLILFPLGKLLNLLPNWKIGYGRFSFYLNSSPFNVKEHAAITIAVSLTSSTAYATNILSAQTSFYKQNLSWGYKILIVLTSQMLGYGFAGLTRRWIVYPAAMIWPQTLVSTVLFRTLHGNSGNDIGVLKNNRISANGWTISRYRFFAYVMIGSFVFYWFPGFIFKGLSYFTVLCWIWPKNRVVNQLFGYNSGLGILPLTFDWQQVVYNSNPLASPWWVICNTFGSVVLIFWIVVPILYYKGVWFSNYLPMLSSSTFDHTGVSYNSSRVLNSDYSFNHTKYESYSPLYMPMSYSMSTALNFAAVTAIFTHCALYNGKDIWQRLWKESGKDECIHRKLMRNYKEAPQWWYATLFIVVFGLTIFTVRYYDTQCPVWALIVALLIFIVNFIPQGVLEGITNQHVGLNIITELIGGYILPGKPLANLMIKLYGFIPMRQGLEFSRDLKLAQYMKIPPRILFFVQLFATILGGITQVAVQEWMNYHIPGICTTSQSNGFTCPNGRSIYNASLIWGAIGPAKMFSKGKPYYPLIFFFLIGAVAPFITWGLRKRFPKSWIGKLNAPVLFTGPGNIPPATGINYSSWAIVGFIFNYVIRKRAIHWWRKYNYVLAAAMDSGVAVAGVVIFLCVSYPGGKITWWGNTVYTKTYDWKSVPYRSLGPNETFGYTNW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MTARNSASI ------CCCCCCCCC		21712547
6	Phosphorylation	--MTARNSASIPTSI --CCCCCCCCCCCCC		25720772
8	Phosphorylation	MTARNSASIPTSIRK CCCCCCCCCCCCCCC		29996109
11	Phosphorylation	RNSASIPTSIRKTSE CCCCCCCCCCCCCCC		25720772
12	Phosphorylation	NSASIPTSIRKTSEN CCCCCCCCCCCCCCC		21712547
16	Phosphorylation	IPTSIRKTSENEVSG CCCCCCCCCCCCCCC		21712547
17	Phosphorylation	PTSIRKTSENEVSGD CCCCCCCCCCCCCCC		25720772
22	Phosphorylation	KTSENEVSGDETPAG CCCCCCCCCCCCCCC		24763107
26	Phosphorylation	NEVSGDETPAGVGNL CCCCCCCCCCCCCCC		25720772
32	N-linked_Glycosylation	ETPAGVGNLSTKTAS CCCCCCCCCCCCCCC		-
34	Phosphorylation	PAGVGNLSTKTASKT CCCCCCCCCCCCCCE		29996109
35	Phosphorylation	AGVGNLSTKTASKTS CCCCCCCCCCCCCEE		29996109
37	Phosphorylation	VGNLSTKTASKTSLT CCCCCCCCCCCEEEE		25720772
39	Phosphorylation	NLSTKTASKTSLTFR CCCCCCCCCEEEEEE		25720772
41	Phosphorylation	STKTASKTSLTFRQS CCCCCCCEEEEEEEC		25720772
42	Phosphorylation	TKTASKTSLTFRQSS CCCCCCEEEEEEECC		25720772
76	Phosphorylation	HPNRPFRTNSSSFSP CCCCCCCCCCCCCCC		29996109
77	N-linked_Glycosylation	PNRPFRTNSSSFSPN CCCCCCCCCCCCCCC		-
78	Phosphorylation	NRPFRTNSSSFSPND CCCCCCCCCCCCCCC		25720772
79	Phosphorylation	RPFRTNSSSFSPNDY CCCCCCCCCCCCCCC		25720772
80	Phosphorylation	PFRTNSSSFSPNDYS CCCCCCCCCCCCCCC		25720772
82	Phosphorylation	RTNSSSFSPNDYSIS CCCCCCCCCCCCCCC		25720772
89	Phosphorylation	SPNDYSISESPSKSK CCCCCCCCCCCCCCC		25720772
91	Phosphorylation	NDYSISESPSKSKKD CCCCCCCCCCCCCCC		25720772
93	Phosphorylation	YSISESPSKSKKDGV CCCCCCCCCCCCCCE		28889911
103	Phosphorylation	KKDGVHVSAVQLDNE CCCCEEEEEEEECCC		25720772
109	N-linked_Glycosylation	VSAVQLDNETDSEVE EEEEEECCCCCHHHH		-
111	Phosphorylation	AVQLDNETDSEVESE EEEECCCCCHHHHHH		25720772
113	Phosphorylation	QLDNETDSEVESEVE EECCCCCHHHHHHHH		25720772
117	Phosphorylation	ETDSEVESEVEELER CCCHHHHHHHHHHHH		25720772
256	N-linked_Glycosylation	QTSFYKQNLSWGYKI CCHHHHHCCCCHHHE		-
452	N-linked_Glycosylation	DHTGVSYNSSRVLNS CCCCCCCCCCCCCCC		-
464	N-linked_Glycosylation	LNSDYSFNHTKYESY CCCCCCCCCCCCCCC		-
691	N-linked_Glycosylation	PNGRSIYNASLIWGA CCCCEEECCHHEEEC		-
843	N-linked_Glycosylation	PYRSLGPNETFGYTN CCCCCCCCCCCCCCC		-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of PGT1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of PGT1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of PGT1_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of PGT1_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.