ECM29_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ECM29_SCHPO
• UniProt AC: Q9P7H8
• Protein Name: Proteasome component ecm29
• Gene Name: ecm29
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 1679
• Subcellular Localization: Cytoplasm . Nucleus .
• Protein Description: Stabilizes the proteasome holoenzyme, probably by tethering the 20S proteolytic core particle and the 19S regulatory particle. The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity)..
• Protein Sequence: MAENELRLLNNAELKLALAESEDSFQSLVSVFLCPILLKLDSPHESVRNKTISIANHIMTRLNNNAQAILPLEALVSQYVEANQPLRKRFLLAFISIGEKRIPCSENLALLQICLNHVNEYPLVLLTLTIRLLRFSKPTSAITCSNDVILSLSSFYLIQKDQRIFSDLQFSQKTVDYRLSLLRWIHLSSWPSNWKWLAYFFASADSHSEVARLADEFTRDSGLPDLENLSHVNVLLDIALDKFRIEALHANFSVSISLRNKAIQHLLKSKIAANTDKAINCIEFILEAPPSMQPRLIQFTRWVVDKADPNFLKPKAAMILEKILSILSSNIIQSDLLRGFLYTTIGLLTKVDNHLITNSLLTNLLTSLQSELPDVRVSIDEALSIIIPYYSNFRFSNELLPVLEPFIFDSPESPAAYCALRFVLVAFPFDYLPARFICLKVQNPFVFHHSFIEEAKKGLNLSQWVQYNSVYSTNEAQEEDKVRAASYPSASEVISFILSDHDLKKFWESNAAEYCLAILEFIERCIYYSADRSLELYDNDKLSSIDALLIQDSKLREMVSEKCISLSNFNVFLEYVFYGTLLMHFEPTYALSRLVSFAPPEVTFSLPELDFLTSVFNFPLALRNTATRILGIILSTKDSTRISEVLSSCFTIISTSNNKNDNFFKAETALLIIGYTISYLAAQTNSAAVDSFILNSGSIKEFFSVLLEYLGSNVLHKKTTSLAIYKELFVYFTRDWITSYGVDFDEILNVLLRFLKEVEDTNVKVECLHVISRMSLSFSDDEMAEKILKAIYVTYHMDSPDILFASAEAMSILAGGHRNVFVKSTCPIFFQKQLDNYKADHYCFTLDFILTDCVNSPKPLLRRASSLWLFYIVRYCEPQTYTMTRLNDIYHSFLSFLVTQDDFVQDTASRGLKAMYDVLEGDERKSFTDNLISTIAADRVDEKTKAPLDADTALFTTNKGTVATYKDICSLASESGNPDLIYSFLSIAGNSSLWQARKGLASGISYLGIPEDQKRKTFSFDTSKSSSLLKKLYRFKHDPNPDVAKTMGEIWDTLVPSDLNLASHRKYLVEDCLEFMGSRSWRDRESSVNTLVSLLSNVPVTEYLNQLEDIWNMSFRTLDDIKESVREASFPLCKLLARSVIQSLEKTSHNTSPSGICKGKRIVSVALPFLLKHAYDQAKEVRSLTYSTITELVRTGNSTLTSFVPAIMQVMLEYLTEYESKAATFLDFHAKNYSIKQENIDNARTSAVQSSSMMDTLEKCIGLLDESSMQTLYPILNRMIAKPGGVPTKIGSAQVVMLLVIRRGPLVKQFASKLLQSLKSSCFDRNAAVSDAFASAIGYLLRVCPLEIASQTCQEIIDKFYDGNTNEQIISSKLTVYASRYAPDVFLNLGSLFFPFIFFGKHSSSISINGVLSKAWDELSSAGSSVNLYSEEIILLIQKNLIVTKWDVKRPAAAALLEFVNTSRLTYRQNDIYVLLNETMKDKSWPGKELLLEAYVKFLIKYPEFIKSQKMEEVHQVIVREFKRRNIVYKSHAMESVGELLSDENYRELDLYELSLNECGTFLQKEWFDKDDELNLEEKIALQRNSVYAMFNSSRPGNKNCNEMLLTYLSNALDENYLHWNVKLAILKNAPHLKKIMSNEEFLLYKDILYRCYEDNPSPKAKDYAEVIFGENYLSVLRN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Oops, there are no PTM records of ECM29_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ECM29_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ECM29_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ECM29_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
POM1_SCHPO	pom1	genetic	18818364
SDS23_SCHPO	sds23	genetic	22681890
MU122_SCHPO	mug122	genetic	22681890
ALF1_SCHPO	alf1	genetic	22681890
ATG11_SCHPO	atg11	genetic	22681890
CAPZB_SCHPO	acp2	genetic	22681890
PFL9_SCHPO	pfl9	genetic	22681890
CAND1_SCHPO	knd1	genetic	22681890
IWR1_SCHPO	iwr1	genetic	22681890
YBD1_SCHPO	SPBC16C6.01c	genetic	22681890

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.