ALF1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ALF1_SCHPO
• UniProt AC: O43078
• Protein Name: ATPase-like fidgetin
• Gene Name: alf1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 660
• Subcellular Localization: Nucleus .
• Protein Sequence: MDSDLDRILPIASRALLCEGNRDWAGAYVSYCKVLEEMKKSSAARDRMGLGPLTGAEACSWNGLYDNCLSKASKLRKTILESEMERQNYQLAAKLSKKAPVDLHPLRPVRSQTPAYTPMTTRMMYRQTRGAQSEVNLSTPKQIYSKHSPPSTSTSSIVSSSYGDAPSYLAPSKPNRSPPLKPEDPFASFNSSASAIAAASKSAAASASALSSDTGRSATMNSTTFPTAMKSQSTTKPTLSNSVSSPSIQVSNNQNANNSTPLSFHAPIPPLHVPAVPLTSASHSSSDGKSRKHPSPYKPYLNSSHDTLGSSTRPSSADTAGSPATSPPATADSKTIVSKTISASTTQQTEPLQQTTPSSDFEYAIMNEIISNHEPVYWSDIAGLDDAKNSLKEAVIYPFLRPELFQGLREPVQGMLLFGPPGTGKTMLARAVATEAKATFFSISASSLTSKYLGDSEKLVRALFEVAKRQTCSVIFVDEIDSILSARNDSGNEHESSRRLKTEFLIQWSSLTNAAPDKQTGHSPRVLVLAATNLPWCIDEAARRRFVKRTYIPLPEKETRYKHLSHLLHNQVHCLTEEDLEELVNLTEGYSGSDITALAKDAAMGPLRNLGDALLTTSAEMIPPISLNHFKASLRTIRPSVSQEGIHRYEEWNKQFGSQR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
111	Phosphorylation	HPLRPVRSQTPAYTP CCCCCCCCCCCCCCC		29996109
113	Phosphorylation	LRPVRSQTPAYTPMT CCCCCCCCCCCCCCC		25720772
133	Phosphorylation	RQTRGAQSEVNLSTP HHCCCCCCCCCCCCC		28889911
138	Phosphorylation	AQSEVNLSTPKQIYS CCCCCCCCCCHHHHC		28889911
148	Phosphorylation	KQIYSKHSPPSTSTS HHHHCCCCCCCCCCH		21712547
151	Phosphorylation	YSKHSPPSTSTSSIV HCCCCCCCCCCHHHH		25720772
153	Phosphorylation	KHSPPSTSTSSIVSS CCCCCCCCCHHHHCC		24763107
159	Phosphorylation	TSTSSIVSSSYGDAP CCCHHHHCCCCCCCC		29996109
160	Phosphorylation	STSSIVSSSYGDAPS CCHHHHCCCCCCCCH		27738172
161	Phosphorylation	TSSIVSSSYGDAPSY CHHHHCCCCCCCCHH		24763107
162	Phosphorylation	SSIVSSSYGDAPSYL HHHHCCCCCCCCHHC		29996109
172	Phosphorylation	APSYLAPSKPNRSPP CCHHCCCCCCCCCCC		27738172
177	Phosphorylation	APSKPNRSPPLKPED CCCCCCCCCCCCCCC		28889911
188	Phosphorylation	KPEDPFASFNSSASA CCCCCCCCCCCCHHH		27738172
217	Phosphorylation	LSSDTGRSATMNSTT HCCCCCCCCCCCCCC		29996109
219	Phosphorylation	SDTGRSATMNSTTFP CCCCCCCCCCCCCCC		29996109
222	Phosphorylation	GRSATMNSTTFPTAM CCCCCCCCCCCCCCC		24763107
223	Phosphorylation	RSATMNSTTFPTAMK CCCCCCCCCCCCCCC		29996109
224	Phosphorylation	SATMNSTTFPTAMKS CCCCCCCCCCCCCCC		29996109
300	Phosphorylation	HPSPYKPYLNSSHDT CCCCCCCCCCCCCCC		27738172
307	Phosphorylation	YLNSSHDTLGSSTRP CCCCCCCCCCCCCCC		27738172
316	Phosphorylation	GSSTRPSSADTAGSP CCCCCCCCCCCCCCC		27738172
322	Phosphorylation	SSADTAGSPATSPPA CCCCCCCCCCCCCCC		21712547
325	Phosphorylation	DTAGSPATSPPATAD CCCCCCCCCCCCCCC		27738172
326	Phosphorylation	TAGSPATSPPATADS CCCCCCCCCCCCCCC		21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ALF1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ALF1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ALF1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MAL3_SCHPO	mal3	genetic	25422470
MBO1_SCHPO	mto1	genetic	25422470

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.