CSN7_SCHPO - dbPTM
CSN7_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CSN7_SCHPO
UniProt AC Q9UUJ7
Protein Name COP9 signalosome complex subunit 7
Gene Name csn71
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 205
Subcellular Localization
Protein Description Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes..
Protein Sequence MEEKISQAIDDPNVFCFQELWIECQEVQKSQPIDSAVLRTLEIFCRGDIRDASSEWNELRFKKLRLLTLIDLANRHVGSSVSFETILVHLQLDRLPPSDPTFTVEYYIMQAMMNQILVGKINAKTQTLHVSWALERFLDSKRIDEMKYSLDRFIERCSNILFQLDAGTPSVSKSFKRASRMSSSDGIDYMVFDKRPRPDDTDFDL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
179PhosphorylationSKSFKRASRMSSSDG
CHHHHHHHHCCCCCC		32.3324763107
182PhosphorylationFKRASRMSSSDGIDY
HHHHHHCCCCCCCCE		26.1124763107
183PhosphorylationKRASRMSSSDGIDYM
HHHHHCCCCCCCCEE		24.0928889911
184PhosphorylationRASRMSSSDGIDYMV
HHHHCCCCCCCCEEE		32.3321712547
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CSN7_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CSN7_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CSN7_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
NSE6_SCHPOnse6genetic
18931302
MCL1_SCHPOmcl1genetic
18818364
SGF29_SCHPOsgf29genetic
18818364
IDHP_SCHPOidp1genetic
22681890
MGR2_SCHPOmgr2genetic
22681890
RAD55_SCHPOrad55genetic
22681890
HRQ1_SCHPOhrq1genetic
22681890
YE08_SCHPOSPAC17H9.08genetic
22681890
PPR8_SCHPOppr8genetic
22681890
YJB1_SCHPOdbl2genetic
22681890
RAD57_SCHPOrad57genetic
22681890
LIZ1_SCHPOliz1genetic
22681890
POF3_SCHPOpof3genetic
22681890
ATP11_SCHPOatp11genetic
22681890
ASK1_SCHPOask1genetic
22681890
TREA_SCHPOntp1genetic
22681890
MCL1_SCHPOmcl1genetic
22681890
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CSN7_SCHPO

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-183, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory