dbPTM

YQ72_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YQ72_SCHPO
UniProt AC	Q76PC4
Protein Name	UPF0649 protein C1442.02
Gene Name	SPCC1442.02, SPCC1450.18
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	562
Subcellular Localization	Cytoplasm . Nucleus .
Protein Description
Protein Sequence	MDWKEAIPGAAKVAIETKDYITYSTLLELILEEARIKDIDEQRELIKCLHEELKQEKNDHITREISWDIIGMVLPYVGKVQNEADEFVDFLAKNGNPREVFLKCCELLINGGFESPQQFISLNSAILSALHRISTKRPVLFVNNFLISLFSGLANILQIDSDELYCVWKISISSIQDAMHRFPVSECYLACLKACSILAQLFLSKETLMLSFRSLLQTKDQYAEFREELSGATTNCDKLDTLSKSIINIFDYLLSHLPESWSIITEHMAQELTKATYVSQSSSISSEDEEIAKNADVPAEVDNNSTKADDKRDEIEFDTKGCLALLTIKSFYQSGNFFLDFLKEKFPSTILETLQQLVSWEIQLDSVGFKDIAVYQGYLLDLPHFQVPDSELEHLSSLLHGYHFMASSTELPWLRVTCNAIVTKCLDSQLPSVRLSYILDTLEECPLLNIKTAILNYYQKQCSLVKDSNEEGLKNFVSPNTLLDVFKVFDAMEDVELDSQSLSYIHQTLVFLYSLEIQNLLSQNQFPTVYFTKISDQINNYEGELPTDGLKYYIELLNSRNK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
281	Phosphorylation	KATYVSQSSSISSED HCHHCCCCCCCCCCC	20.67	25720772
282	Phosphorylation	ATYVSQSSSISSEDE CHHCCCCCCCCCCCH	24.85	25720772
283	Phosphorylation	TYVSQSSSISSEDEE HHCCCCCCCCCCCHH	31.56	21712547
285	Phosphorylation	VSQSSSISSEDEEIA CCCCCCCCCCCHHHH	29.62	28889911
286	Phosphorylation	SQSSSISSEDEEIAK CCCCCCCCCCHHHHH	47.61	28889911
305	Phosphorylation	PAEVDNNSTKADDKR CCCCCCCCCCCCCCC	37.22	24763107
306	Phosphorylation	AEVDNNSTKADDKRD CCCCCCCCCCCCCCC	32.16	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YQ72_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YQ72_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YQ72_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YQ72_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YQ72_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-285 AND SER-286, ANDMASS SPECTROMETRY.	18257517 [Abstract]