GYP51_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GYP51_SCHPO
• UniProt AC: Q10496
• Protein Name: GTPase activating protein Gyp51
• Gene Name: gyp51
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 1031
• Subcellular Localization: Membrane ; Single-pass membrane protein . Cytoplasm .
• Protein Description: GTPase-activating protein involved in ER to Golgi trafficking and polarized exocytosis..
• Protein Sequence: MAFTEANEREVQSSYEKENVKIIREEEAKDQESTDDIAVEDGTGTSPDLNFFSTQNVMQMNFEDEYSEFSNEDDEAEIDNSFADSIPNEPEIPDMQDEYSRDSHSQQSVEEQNNTTNTDEDASVNEFSVAADISDVNTLGKDNSESTEEPVNEVNETATLGNEDVGERSGFPSEGLDNEPESQRDLDETGNLAPEDLKDEVKSVHEFNEPNDLRQQEESYSDDDDTNVNEFEDVNEIENEHQLSVADEDQTSRLVKGKMIFVGKEDFGEEADISNSVFIEQNGPNSDTVSGFKETSSIVNSSSTTEKPGVALDSQNDTSIFNEEQTNSLTETFNDLTLDHLPENVESEPVAGKENETAKNESGASDNDHKANVHVFVLKSSEDAITLNEEKIATQDDPLEAPTPIVASSSTIFLNSNQRNDELSASGSQEPHPKDGTNSTSSLPLDTNNLSNSEPPSHVLDASSETIEVIQTIKKLQNQVPETIKDEVGKKNTAFSPGTSLSTNHVKTKSRSAHNNSTSPFSTAVSSWLNPLRYPSDKSPRVISSYLESVFISKPRSIGDAQKLEILEYLQSQSSTVSNQVFTLLSNFIQNPLFVLDECFDEFRNLILMHNSHTVHTVVWKTISSWTSYDYEMQYSSLSIKNCDSDKAIRKDLDRTFAPEILSHFFSNRQQLEPTDNIAESTANLHRVLRSLAIVLPQVGYTQGMSWIAGALLMHLPAPQAFALLVFLFKNYHLQNIFSSEMRGLSRVLHQFTRLVEDYMPSLAIHFKRQDIKTCSYASEWFLTLFAYKFPLEVVAHLYDILFLYGPGILFNFGLALLSHSQESLLKLNMDRLISYLKEDIFLAFKETQEGENYDTSLFVKTAFSFEIQPDVLDRYGNEYDILLKSEHELDSSLEEMRNRHKSLNEHFIMLSDSMANLQVEHENMSALLLKEKMYLKNQTVEQASLKSEIASLNSQLAKQKSEIEQAFQGDMEAIIAENLEIMVESQSLEDEIFRKEKQLAETKVNLAVLDEDHMMALQKWSQLMNRIKTK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
159	Phosphorylation	NEVNETATLGNEDVG CCHHHHHCCCCCCCC		25720772
169	Phosphorylation	NEDVGERSGFPSEGL CCCCCCCCCCCCCCC		29996109
203	Phosphorylation	DLKDEVKSVHEFNEP HHHHHHHHHHCCCCC		28889911
297	Phosphorylation	SGFKETSSIVNSSST CCCEECHHHHCCCCC		21712547
386	Phosphorylation	KSSEDAITLNEEKIA ECCCCCEECCHHHCC		27738172
409	Phosphorylation	PTPIVASSSTIFLNS CCCEEEECCEEECCC		27738172
424	Phosphorylation	NQRNDELSASGSQEP CCCCCCCCCCCCCCC		25720772
426	Phosphorylation	RNDELSASGSQEPHP CCCCCCCCCCCCCCC		25720772
428	Phosphorylation	DELSASGSQEPHPKD CCCCCCCCCCCCCCC		25720772
496	Phosphorylation	GKKNTAFSPGTSLST CCCCCCCCCCCCCCC		25720772
499	Phosphorylation	NTAFSPGTSLSTNHV CCCCCCCCCCCCCCC		24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GYP51_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GYP51_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GYP51_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of GYP51_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.