dbPTM

LNP_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	LNP_SCHPO
UniProt AC	O94414
Protein Name	Endoplasmic reticulum junction formation protein lunapark {ECO:0000305}
Gene Name	lnp1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	334
Subcellular Localization	Endoplasmic reticulum membrane Multi-pass membrane protein . Golgi apparatus membrane Multi-pass membrane protein . Localizes to three-way ER tubule junctions..
Protein Description	Plays a role in tubular endoplasmic reticulum network formation and maintenance..
Protein Sequence	MGWFFQKKKEFDFGGELDRLEMKLEEAQYNIDNIQSQKKKILFRYTVCSLAIYTIGMAVWASRSSILFQHPLFSKLFRISLYILGVFSLYMFRWAIAWFCEKRLSRARMNLHKLNAEKRKILDALKSRKEYFETQALLEKYGEQPTLAQKKLSNAAAAKSVPGSSSSSSDPMHPQHWYDRVLEGLVGANENSENNREALICSHCFHHNGLASYGEKASDVRYVCLFCKAWNGPPIDKSLPSSEMDSNLQTNPSSISKGKKNNSNNTTQKGPNIISSPQVINASSPVRKAGKKKSKKALPTSPLSSSSPDASYNSVSDSFHTVAASVPESLTPTK

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
275	Phosphorylation	QKGPNIISSPQVINA CCCCCCCCCCCEECC	31.97	21712547
276	Phosphorylation	KGPNIISSPQVINAS CCCCCCCCCCEECCC	14.67	24763107
283	Phosphorylation	SPQVINASSPVRKAG CCCEECCCCCCHHCC	30.59	21712547
284	Phosphorylation	PQVINASSPVRKAGK CCEECCCCCCHHCCC	25.63	28889911
305	Phosphorylation	LPTSPLSSSSPDASY CCCCCCCCCCCCCCC	42.38	25720772
306	Phosphorylation	PTSPLSSSSPDASYN CCCCCCCCCCCCCCC	42.38	25720772
307	Phosphorylation	TSPLSSSSPDASYNS CCCCCCCCCCCCCCC	28.84	27738172
329	Phosphorylation	VAASVPESLTPTK-- HHHCCCHHCCCCC--	31.32	29996109
333	Phosphorylation	VPESLTPTK------ CCHHCCCCC------	44.12	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of LNP_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of LNP_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of LNP_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of LNP_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of LNP_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-284, AND MASSSPECTROMETRY.	18257517 [Abstract]