SCE3_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SCE3_SCHPO
• UniProt AC: O14369
• Protein Name: Probable RNA-binding protein sce3
• Gene Name: sce3
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 388
• Subcellular Localization: Cytoplasm.
• Protein Sequence: MGPKKSTKMSLNAFLGDESFGSTNWADDIDDLPALPQDRTTSTYRATPSSADAGYNAPSSTFESVRSPPESRREGGMGSGYQRDAIPIPSEPPFTAHVGNLSFDLTENDLGDFFGEGVTSIRLVIDPLTERSRGFGYVEFETADTLSAALALSGEDLMGRPVRITVAEPRRSFAREERSTGDWVRRGPLPPAEPAESPFGKRRTNSGRFRDPARDPSDRVREEPREWVRRGPLPPRESSERPRLNLKPRSSSNVNTEATPSATTTTSSKPKRDPFGGAKPVDNTSVLQRVEEKLAKRTQSFRREDNANRERSTSRKPSADKAEKTDKTDAIAEKVSDIRLGDGEKKSSETDSEVAATKTPATEDAPATNAGEAEEEEGWTKIGKGRKH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	PKKSTKMSLNAFLGD CCCCCCCHHHHHHCC	21.74	29996109
47	Phosphorylation	TTSTYRATPSSADAG CCCEEECCCCCCCCC	18.07	28889911
49	Phosphorylation	STYRATPSSADAGYN CEEECCCCCCCCCCC	33.53	28889911
50	Phosphorylation	TYRATPSSADAGYNA EEECCCCCCCCCCCC	31.22	28889911
59	Phosphorylation	DAGYNAPSSTFESVR CCCCCCCCCCHHHCC	39.33	25720772
60	Phosphorylation	AGYNAPSSTFESVRS CCCCCCCCCHHHCCC	35.74	28889911
61	Phosphorylation	GYNAPSSTFESVRSP CCCCCCCCHHHCCCC	35.44	28889911
64	Phosphorylation	APSSTFESVRSPPES CCCCCHHHCCCCCHH	20.74	28889911
67	Phosphorylation	STFESVRSPPESRRE CCHHHCCCCCHHHCC	42.52	28889911
71	Phosphorylation	SVRSPPESRREGGMG HCCCCCHHHCCCCCC	42.27	28889911
179	Phosphorylation	SFAREERSTGDWVRR HHCCHHHCCCCHHHC	39.77	25720772
180	Phosphorylation	FAREERSTGDWVRRG HCCHHHCCCCHHHCC	45.43	25720772
197	Phosphorylation	PPAEPAESPFGKRRT CCCCCCCCCCCCCCC	27.86	28889911
250	Phosphorylation	RLNLKPRSSSNVNTE CCCCCCCCCCCCCCC	46.80	28889911
251	Phosphorylation	LNLKPRSSSNVNTEA CCCCCCCCCCCCCCC	27.49	28889911
252	Phosphorylation	NLKPRSSSNVNTEAT CCCCCCCCCCCCCCC	46.15	28889911
256	Phosphorylation	RSSSNVNTEATPSAT CCCCCCCCCCCCCCC	23.78	21712547
259	Phosphorylation	SNVNTEATPSATTTT CCCCCCCCCCCCCCC	16.14	29996109
263	Phosphorylation	TEATPSATTTTSSKP CCCCCCCCCCCCCCC	29.07	28889911
267	Phosphorylation	PSATTTTSSKPKRDP CCCCCCCCCCCCCCC	33.98	27738172
284	Phosphorylation	GAKPVDNTSVLQRVE CCCCCCCHHHHHHHH	18.75	24763107
285	Phosphorylation	AKPVDNTSVLQRVEE CCCCCCHHHHHHHHH	27.38	25720772
318	Phosphorylation	RSTSRKPSADKAEKT HHCCCCCCHHHHHHC	52.73	25720772
336	Phosphorylation	DAIAEKVSDIRLGDG HHHHHHHHCCCCCCC	38.09	25720772
347	Phosphorylation	LGDGEKKSSETDSEV CCCCCCCCCCCHHHH	44.46	28889911
348	Phosphorylation	GDGEKKSSETDSEVA CCCCCCCCCCHHHHH	54.09	24763107
350	Phosphorylation	GEKKSSETDSEVAAT CCCCCCCCHHHHHCC	46.93	25720772
352	Phosphorylation	KKSSETDSEVAATKT CCCCCCHHHHHCCCC	41.20	28889911
357	Phosphorylation	TDSEVAATKTPATED CHHHHHCCCCCCCCC	26.22	29996109
359	Phosphorylation	SEVAATKTPATEDAP HHHHCCCCCCCCCCC	17.50	24763107
362	Phosphorylation	AATKTPATEDAPATN HCCCCCCCCCCCCCC	35.28	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SCE3_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SCE3_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SCE3_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of SCE3_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-49; SER-50; SER-60;THR-61; SER-64; SER-67; SER-71; SER-197; SER-250; SER-251; SER-252 ANDSER-347, AND MASS SPECTROMETRY.
PubMed: 18257517