| UniProt ID | DPOZ_SCHPO | |
|---|---|---|
| UniProt AC | Q9P6L6 | |
| Protein Name | DNA polymerase zeta catalytic subunit | |
| Gene Name | rev3 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 1480 | |
| Subcellular Localization | Mitochondrion . Nucleus . | |
| Protein Description | Nonessential DNA polymerase. Required for DNA damage induced mutagenesis. Involved in DNA repair, mitochondrial DNA repair and translesion synthesis. Has a role in the bypass of abasic (AP) sites (By similarity).. | |
| Protein Sequence | MRFSIEYIDWELSPCDPAYDFVGKDLPTANEELTTVPVIRVFGLNEEAETVCCFIHNVFPYIYVEYSSFAETLDLEVPDFLSQLQTSINYALALAARANPETYKPAVQSVQLVKGIPFYGYSFCFQKFLKICLFSPKNRDRLVDLFRQGAILNKVIQVYESHLPYLLQFMVDHNLYGCAPIDLDDSIIKRDDLLSFCNVEVHVSPNAILNACWLSERNIHTDLYETHASSPNSLLVTSLAEIWKSEASRRNLTSSDETNSFSKLHQSQFGLKEESSHEPRSSQHWKNEVAMKDLLKNLIKSKLESSSDVNTPLIFDPWPELPTIYSAIHTKDYVRPSQNDISVSQISVDEKICTSYESLPKIQLEQNTAPVIESSFEQLDSELERILGDTLFDSFPYVEPNVDRSKFPKSPLNSSQEVTIHSSQDRQSPPSSPLKDVPSQINPFSPSLRLKGGSPITKREIEFCRDLPNRPTSSEPNQGDTRKAGKRLKYSRNLDDYHICTQIPEDYSPKFLSQHESFVYKQQPPSTDDLYGTMKKLKIPFSIPTNVHYSSEKDIPSYSQEYLGKSHYPIGVSSRYLPEFQSDGSVSEKVRLNPLKLSNFHGERTWQYIKPAPLAVDLSNLESKEAVSEEIQSPQRLSRSKVFRKDPYSCVRILALELFCCSHGGLTPDPTKDSIECCFWAYQEDVNSSMIDRVGFIVVDKSASNSSFGRSFPSCTVLVVNSELELINEVIGLNRQLDPTIVCGYEVHNSSWGYLIERASYRFNYDLPEQLSRLKCTSKANFAKKENAWKYTTTSSINIVGRHVLNIWRILRGEVNLLNYSLENVVLNIFKKQTPYYNQADKVHLWQSSRFHEKQILLNYMLNRTRYCLEILSACAIVTKIREQARIIGIDFMSVISRGSQFKVESIMFRIAKPENYIFPSPSAKQVAEQNALEALPLVMEPKSDLYNNPVVVLDFQSLYPSIIIAYNLCYSTCLGPVKIVNGKVKLGFMFHSSNPNIVNLIKNDVYISPNGYAYVKENVRKSLLAKMLEELIETRNMVKRGMKDCDSDYVNKVLNSRQLALKLIANVTYGYTSASFSGRMPCSEIADTIVETGREILSYSLEYINTLDFCHAKVVYGDTDSLFVELPGATKEQAFDIGQQLANNITSRFPSPIRLKFEKIYFPCFLLAKKRYVGFKFESVSQKAPIFEAKGIETVRRDGTPVQQQLLRRCLEILFKTKDLSTVKKEFQNVCYQIMSGNVPVMDFCFSKEVRLEKYKELSTAPPGAVMARRLMTKDPRREPQYGERVPYLIIAAAPGTTLANRSVAPEEFLSSSFSQLDINYYINNSLIPPLDRFLNLLGASAQSWYHEMPKPRTSLKLTETVKGGIQKKTLDTFLMEKLCSSCLKNNIEIIPDKINSLCSDCLKNPCATISKAVTQHNAYNKKLSLLFDICRGCSKLSSSDPVLCKSNSCKVYYDRAKTENYAKVQAEMLTKTLGSLDW | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of DPOZ_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of DPOZ_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of DPOZ_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of DPOZ_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| REV1_SCHPO | rev1 | genetic | 20453833 | |
| HSK1_SCHPO | hsk1 | genetic | 20176980 | |
| EXO1_SCHPO | exo1 | genetic | 18818364 | |
| ABP1_SCHPO | cbp1 | genetic | 18818364 | |
| ARP6_SCHPO | arp6 | genetic | 22681890 | |
| CTBL1_SCHPO | SPAC1952.06c | genetic | 22681890 | |
| RAD55_SCHPO | rad55 | genetic | 22681890 | |
| SNF5_SCHPO | snf5 | genetic | 22681890 | |
| RAD57_SCHPO | rad57 | genetic | 22681890 | |
| FFT3_SCHPO | fft3 | genetic | 22681890 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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