dbPTM

YGBA_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YGBA_SCHPO
UniProt AC	O74782
Protein Name	Universal stress protein A family protein C25B2.10
Gene Name	SPBC25B2.10
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	307
Subcellular Localization	Barrier septum . Cell tip .
Protein Description
Protein Sequence	MSESAPAGSKEGVSFGNLPRPEPRTSKDQQKLSISTDVKKPSHSAPVTPVRSARSSMEQPTFRPVAKNSVTVAPARAAGFCPPQFEEYHHGRSHSLVSPPPSPHFLKRISFDTFNNKAATDFSLTLKTQHQAYKWTRTSRTFLCGMDGNSYSEVAVDWLFETLLADNDEAVVLRVIDPSSKLAEDLSDEQSYRSLAEHIMAGILKKVDDDKAVSIIVELVVGKPQDMILRTIHVYSPDSLIVGTRGKALNSFQSLLSSGSVSKFCLQKSPIPVIVVRPDRKRVRSKNKRLKDKTRKSYMEILEKSGR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
25	Phosphorylation	LPRPEPRTSKDQQKL CCCCCCCCCHHHCCE	51.33	21712547
26	Phosphorylation	PRPEPRTSKDQQKLS CCCCCCCCHHHCCEE	35.20	21712547
35	Phosphorylation	DQQKLSISTDVKKPS HHCCEEEECCCCCCC	18.38	29996109
36	Phosphorylation	QQKLSISTDVKKPSH HCCEEEECCCCCCCC	43.04	29996109
42	Phosphorylation	STDVKKPSHSAPVTP ECCCCCCCCCCCCCC	38.67	25720772
44	Phosphorylation	DVKKPSHSAPVTPVR CCCCCCCCCCCCCCC	38.31	28889911
48	Phosphorylation	PSHSAPVTPVRSARS CCCCCCCCCCCCCCC	18.27	28889911
52	Phosphorylation	APVTPVRSARSSMEQ CCCCCCCCCCCCCCC	28.41	25720772
55	Phosphorylation	TPVRSARSSMEQPTF CCCCCCCCCCCCCCC	33.48	29996109
56	Phosphorylation	PVRSARSSMEQPTFR CCCCCCCCCCCCCCC	22.30	25720772
61	Phosphorylation	RSSMEQPTFRPVAKN CCCCCCCCCCCCCCC	31.78	29996109
93	Phosphorylation	EEYHHGRSHSLVSPP HHCCCCCCCCCCCCC	23.24	25720772
95	Phosphorylation	YHHGRSHSLVSPPPS CCCCCCCCCCCCCCC	31.54	29996109
98	Phosphorylation	GRSHSLVSPPPSPHF CCCCCCCCCCCCHHH	36.66	28889911
102	Phosphorylation	SLVSPPPSPHFLKRI CCCCCCCCHHHHHEE	36.46	28889911
110	Phosphorylation	PHFLKRISFDTFNNK HHHHHEEEEECCCCC	22.54	24763107

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YGBA_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YGBA_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YGBA_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YGBA_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YGBA_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-44; THR-48; SER-98 ANDSER-102, AND MASS SPECTROMETRY.	18257517 [Abstract]