GLYD_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: GLYD_SCHPO
• UniProt AC: O13972
• Protein Name: Probable serine hydroxymethyltransferase, cytosolic
• Gene Name: SPAC24C9.12c
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 467
• Subcellular Localization: Cytoplasm .
• Protein Description: Interconversion of serine and glycine..
• Protein Sequence: MSSNDSIMLTPLKEQDPTVAEIMRHEADRQRSSVVLIASENFTSRAVMDALGSVMSNKYSEGYPGARYYGGNKFIDQIETLCQERALAAFNLDPAKWGVNVQCLSGSPANMQVYQAIMPPHGRLMGLDLPSGGHLSHGYQTDTKKISAVSTYFESMPYRVDPNTGLIDYDMLEHDAQLFRPKILVAGTSAYCRLIDYARMRQIADSVNAYLVVDMAHISGLVSAGVIPSPFEYADVVTTTTHKSLRGPRGAMIFFRRGLRKHDKKGNPIYYDLEDKINFSVFPGHQGGPHNHTITALAVALKQCQEPAYKEYQAQVVKNAKVCEEEFKKRGYKLAADGTDSHMVLVDVKSKGVDGARAERVLELINIVTNKNTVPSDKSAFSPSGIRVGTPAMTTRGFKEQDFVRVVDYIDRALTFAANLQKELPKDANKLKDFKAKLGEGEQYPELVQLQKEVAEWASSFPLADKW

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Phosphorylation	------MSSNDSIML ------CCCCCCEEE	37.54	29996109
3	Phosphorylation	-----MSSNDSIMLT -----CCCCCCEEEE	43.27	29996109
6	Phosphorylation	--MSSNDSIMLTPLK --CCCCCCEEEECCC	17.72	24763107
10	Phosphorylation	SNDSIMLTPLKEQDP CCCCEEEECCCCCCC	14.81	24763107
189	Phosphorylation	KILVAGTSAYCRLID CEEEECCHHHHHHHH	19.14	25720772
243	N6-(pyridoxal phosphate)lysine	VVTTTTHKSLRGPRG EEEEECCHHHCCCCC	49.44	-
243	Other	VVTTTTHKSLRGPRG EEEEECCHHHCCCCC	49.44	-
376	Phosphorylation	TNKNTVPSDKSAFSP CCCCCCCCCCCCCCC	54.02	25720772
379	Phosphorylation	NTVPSDKSAFSPSGI CCCCCCCCCCCCCCC	39.27	25720772
382	Phosphorylation	PSDKSAFSPSGIRVG CCCCCCCCCCCCEEC	20.20	25720772
384	Phosphorylation	DKSAFSPSGIRVGTP CCCCCCCCCCEECCC	45.73	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of GLYD_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of GLYD_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of GLYD_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GLYD_SCHPO	SPAC24C9.12c	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.