dbPTM

GYP7_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	GYP7_SCHPO
UniProt AC	Q9UUH7
Protein Name	GTPase-activating protein gyp7
Gene Name	gyp7 {ECO:0000312\|EMBL:CAB52727.1}
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	743
Subcellular Localization	Cytoplasm . Nucleus .
Protein Description	Most effectively accelerates the intrinsic GTPase activity of ypt7..
Protein Sequence	MTTLESLDMPEMTEVEDDTVDIHIDNSKVALLFSKSKVFVHPTSKMKDNISGYLSLSKSKALGNSSVAGSDILLSWVPDSFLKNRPRDLSVFQNAETLSNGSIREWVEIPQHLDYSFSVRLCSIYSIIFRPPRYGWNYGSIVINLRDSGESLPPLFFHDDECISTIEYGKQITRDRFDPFDESGNMFWGGTHLLMQLKKYASLEQSSHESQLYLVNPSPEDTVAFQSVELQKVISNNRLNSSSTPPTPRSSSSIFNPFRRALHDLSFTVLERFSRVTNYGKSEVDRLMEHKVTKSILPHLPRELQVLLESKRVQKLTEEYDPARMFLARWAEGIVEQSESNNSQPVNNAGVWTDAQREEDSSLGPFELVYIEERVKRDDPLSVEQWNSMFNAHGKLQVDVHRVLGIIFHGGIQPSLRKEVWPFLLSVYPWDSTSEERRVIYLSLQEEYCTLKRKWYEDIHKQFNDRWFIEQRNRIEKDVHRTDRQHEYFQIEDLPHPDPQSTFTGTNMNMEMMKDILLTYNEYDTELGYVQGMSDLLAPIYVTFNDNALTFWGMVGLMKRLHFNFLRDQSGMHRQLDTLRLLIEFMDPELFAHLEKTDSSNLFCFFRMLLIYFKREFDWEVLLKLWDVLFTNYLSYDYHIFVAYAIAERHREVLLNQTSAFDEVLKYFNELSGKLALEPTLICAEQCFYQFKNKLALIDRKQMEETNSDEDGSKETDLPTIAPYLRNLLKTSQPQYTPSGKQE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
57	Phosphorylation	ISGYLSLSKSKALGN CCCEEEECCCCCCCC	31.35	27738172
59	Phosphorylation	GYLSLSKSKALGNSS CEEEECCCCCCCCCC	21.56	27738172
235	Phosphorylation	VELQKVISNNRLNSS EEEHHHHHCCCCCCC	30.92	25720772
242	Phosphorylation	SNNRLNSSSTPPTPR HCCCCCCCCCCCCCC	36.84	25720772
243	Phosphorylation	NNRLNSSSTPPTPRS CCCCCCCCCCCCCCC	44.76	25720772
244	Phosphorylation	NRLNSSSTPPTPRSS CCCCCCCCCCCCCCC	34.92	25720772
247	Phosphorylation	NSSSTPPTPRSSSSI CCCCCCCCCCCCCCC	32.32	25720772
706	Phosphorylation	DRKQMEETNSDEDGS EHHHHHHHCCCCCCC	27.07	21712547
708	Phosphorylation	KQMEETNSDEDGSKE HHHHHHCCCCCCCCC	50.20	25720772
713	Phosphorylation	TNSDEDGSKETDLPT HCCCCCCCCCCCCCH	39.37	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of GYP7_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of GYP7_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of GYP7_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of GYP7_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of GYP7_SCHPO

Related Literatures of Post-Translational Modification