YGVA_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: YGVA_SCHPO
• UniProt AC: O43024
• Protein Name: CUE domain-containing protein C354.10
• Gene Name: SPBC354.10
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 963
• Subcellular Localization: Cytoplasm .
• Protein Sequence: MSENKKFRPKKVGNTEQVSEKQHTDTALNISQDNKTSSSSAKRGAKGRRGTKGKSGPANSSQTSNIEGSNALELEFDRDSQLSVLQELFPSWTIDDLSFALEEADRDLELTILHITEGHASKWGEVKKKPIPKTKSKPTSHAPVSDNVSSTFRNATRKSKKPSASKDTSRGVRKSKAGAPSDPSSVHAPSSLEKPAGTGDLPSSEISTKAPASTTVSSSVDPGTINEDSSMKDHTTSNEQASVLTSANTAASTNTNGTAGGTSASAKSTSAADQAVASSKPIKKAWASVAKSKKKVTPAPAPAPESEPSKPSIAPSQPSKTNVSAAYEKPAELSSSSVPFPHKSQDSATPANVETTPSTATSAPKKSTAPFAINAVKPAPGLSNISSASLPKPSFAKQAAVGSQSSTTSMTTARLLSDRFPVVMPVANTAAIPEKVQVRFGSLTLGGEDKKSTKSSSDNIAQSGPRSSYFPKKTVSPKPEAKKEASKVAESTKIPKKQHTSAYESRAPQSKVPENLKESHVNETPYRGLHDVNLPASGNASSVSAIPPQVSAQTTIPAASTSATSGPVVGKQSAGYGGIYSPATHGISPQPYAGASLIPPSTGAAFNNETASSNAGETTALPYSSRFMNPVENRSANSPFDNFQHIDHSTELGYASNTSQQYQQTSHPAYTTMSPIEYGQAAPAAHYYNERNQYSQYDNVAGSASNTPDVHSVMHNKVASSNATSLPAAGTATPSPVVSQQQPQPYAFPPMYPIPYVSYGYGTMPYNNNKFGQPQQGYMSQSGFNDFPPIFGGHSNVYNRQQPGNVSGMSGTQTSNPINNATANTSGMTEKAAGHRDSVIGNGGVTGANSMSSTLGGLSSMSGMGRAAPGMFMGNVGSFENLSANAASPYGLPPQQTPLTNAATQQTTSFQSNANKVNNANSQPAGFPFNSGASTNAGSNGLGGYNAYNQSFINRPGGWYGNA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
140	Phosphorylation	KTKSKPTSHAPVSDN CCCCCCCCCCCCCCC	26.61	25720772
145	Phosphorylation	PTSHAPVSDNVSSTF CCCCCCCCCCHHHHH	23.55	29996109
149	Phosphorylation	APVSDNVSSTFRNAT CCCCCCHHHHHHHHC	29.89	29996109
150	Phosphorylation	PVSDNVSSTFRNATR CCCCCHHHHHHHHCC	27.55	29996109
151	Phosphorylation	VSDNVSSTFRNATRK CCCCHHHHHHHHCCC	21.07	29996109
181	Phosphorylation	KSKAGAPSDPSSVHA HHCCCCCCCHHHCCC	62.71	28889911
184	Phosphorylation	AGAPSDPSSVHAPSS CCCCCCHHHCCCCCC	50.40	24763107
185	Phosphorylation	GAPSDPSSVHAPSSL CCCCCHHHCCCCCCC	24.26	29996109
190	Phosphorylation	PSSVHAPSSLEKPAG HHHCCCCCCCCCCCC	48.62	29996109
191	Phosphorylation	SSVHAPSSLEKPAGT HHCCCCCCCCCCCCC	39.22	29996109
204	Phosphorylation	GTGDLPSSEISTKAP CCCCCCHHHCCCCCC	36.69	21712547
207	Phosphorylation	DLPSSEISTKAPAST CCCHHHCCCCCCCCC	21.58	21712547
218	Phosphorylation	PASTTVSSSVDPGTI CCCCEECCCCCCCCC	30.00	27738172
224	Phosphorylation	SSSVDPGTINEDSSM CCCCCCCCCCCCCCC	26.47	29996109
229	Phosphorylation	PGTINEDSSMKDHTT CCCCCCCCCCCCCCC	26.59	21712547
230	Phosphorylation	GTINEDSSMKDHTTS CCCCCCCCCCCCCCC	42.02	21712547
268	Phosphorylation	GTSASAKSTSAADQA CCCCCCCCCHHHHHH	27.58	29996109
270	Phosphorylation	SASAKSTSAADQAVA CCCCCCCHHHHHHHH	28.66	21712547
279	Phosphorylation	ADQAVASSKPIKKAW HHHHHHCCCHHHHHH	32.48	24763107
306	Phosphorylation	APAPAPESEPSKPSI CCCCCCCCCCCCCCC	54.47	29996109
309	Phosphorylation	PAPESEPSKPSIAPS CCCCCCCCCCCCCCC	53.82	29996109
312	Phosphorylation	ESEPSKPSIAPSQPS CCCCCCCCCCCCCCC	34.81	21712547
319	Phosphorylation	SIAPSQPSKTNVSAA CCCCCCCCCCCCCHH	44.46	21712547
344	Phosphorylation	SVPFPHKSQDSATPA CCCCCCCCCCCCCCC	35.86	29996109
349	Phosphorylation	HKSQDSATPANVETT CCCCCCCCCCCCCCC	27.21	29996109
355	Phosphorylation	ATPANVETTPSTATS CCCCCCCCCCCCCCC	39.46	24763107
356	Phosphorylation	TPANVETTPSTATSA CCCCCCCCCCCCCCC	11.18	29996109
362	Phosphorylation	TTPSTATSAPKKSTA CCCCCCCCCCCCCCC	39.86	29996109
387	Phosphorylation	PGLSNISSASLPKPS CCCCCCCCCCCCCCC	20.34	27738172
389	Phosphorylation	LSNISSASLPKPSFA CCCCCCCCCCCCCHH	47.34	24763107
405	Phosphorylation	QAAVGSQSSTTSMTT HHHCCCCCCCCHHHH	31.20	25720772
406	Phosphorylation	AAVGSQSSTTSMTTA HHCCCCCCCCHHHHH	28.24	27738172
417	Phosphorylation	MTTARLLSDRFPVVM HHHHHHHHCCCCEEE	31.19	27738172
442	Phosphorylation	KVQVRFGSLTLGGED CEEEEECCEECCCCC	18.57	28889911
444	Phosphorylation	QVRFGSLTLGGEDKK EEEECCEECCCCCCC	25.67	21712547
455	Phosphorylation	EDKKSTKSSSDNIAQ CCCCCCCCCCCCHHH	34.85	24763107
456	Phosphorylation	DKKSTKSSSDNIAQS CCCCCCCCCCCHHHH	43.18	25720772
457	Phosphorylation	KKSTKSSSDNIAQSG CCCCCCCCCCHHHHC	41.59	25720772
467	Phosphorylation	IAQSGPRSSYFPKKT HHHHCCCHHHCCCCC	32.30	25720772
474	Phosphorylation	SSYFPKKTVSPKPEA HHHCCCCCCCCCHHH	32.13	28889911
476	Phosphorylation	YFPKKTVSPKPEAKK HCCCCCCCCCHHHHH	32.22	28889911
519	Phosphorylation	VPENLKESHVNETPY CCCCHHHHCCCCCCC	31.02	29996109
524	Phosphorylation	KESHVNETPYRGLHD HHHCCCCCCCCCCCC	22.03	29996109
576	Phosphorylation	VGKQSAGYGGIYSPA CCCCCCCCCCCCCCC	16.34	27738172
592	Phosphorylation	HGISPQPYAGASLIP CCCCCCCCCCCCCCC	16.66	27738172
610	Phosphorylation	GAAFNNETASSNAGE CCCCCCCCCCCCCCC	33.68	27738172
695	Phosphorylation	YNERNQYSQYDNVAG CCCCCCCCCCCCCCC	16.70	29996109
697	Phosphorylation	ERNQYSQYDNVAGSA CCCCCCCCCCCCCCC	11.98	29996109
703	Phosphorylation	QYDNVAGSASNTPDV CCCCCCCCCCCCCCH	20.84	28889911
705	Phosphorylation	DNVAGSASNTPDVHS CCCCCCCCCCCCHHH	42.82	25720772
707	Phosphorylation	VAGSASNTPDVHSVM CCCCCCCCCCHHHHH	20.54	29996109
712	Phosphorylation	SNTPDVHSVMHNKVA CCCCCHHHHHHHCCC	22.45	29996109
735	Phosphorylation	AAGTATPSPVVSQQQ CCCCCCCCCCCCCCC	26.44	27738172
739	Phosphorylation	ATPSPVVSQQQPQPY CCCCCCCCCCCCCCC	23.62	27738172
878	Phosphorylation	MFMGNVGSFENLSAN CCCCCCCCCCCCCCC	25.71	27738172

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of YGVA_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of YGVA_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of YGVA_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of YGVA_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-474 AND SER-476, ANDMASS SPECTROMETRY.
PubMed: 18257517