dbPTM

AATC_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	AATC_SCHPO
UniProt AC	O42652
Protein Name	Aspartate aminotransferase, cytoplasmic
Gene Name	aat2 {ECO:0000250\|UniProtKB:P23542}
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	409
Subcellular Localization	Cytoplasm .
Protein Description	Plays a key role in amino acid metabolism..
Protein Sequence	MSDYGFANIEEAKADAIFKLNAQYHQDEDPKKVNMSVGAYRDDTGKPWILPAVKKASKIVEEQASFNHEYLPIAGLPRFTKAAAEVLFRPNPHLLSEDRVASMQSVSGTGANFLAASFIETFYVKHTGAHVYISNPTWPVHRTLWEKLGVTVDTYPYWDAKNRSFDYEGMLSTIKSAPEGSIFLLHACAHNPTGIDPTREQWLSIFESLLSRKHLVVFDIAYQGFASGDLNRDSWALNEFVKYNKDFFVCQSFAKNMGLYGERTGCMHYVAKDASTKNKVLSQLCIVQRNTISNPPAYGARIAAEILNSPQLFAEWEQDLKTMSSRIIEMRKRLRDSLVALKTPGSWDHITQQIGMFSFTGLTPAQVQFCQERYHLYFSANGRISMAGLNNSNVEHVAQAFNHAVRELP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MSDYGFANI ------CCCCCCCCH	39.27	-
2	Phosphorylation	------MSDYGFANI ------CCCCCCCCH	39.27	24763107
4	Phosphorylation	----MSDYGFANIEE ----CCCCCCCCHHH	13.56	19547744
164	Phosphorylation	YWDAKNRSFDYEGML CCCCCCCCCCCCHHH	31.68	25720772
255	N6-(pyridoxal phosphate)lysine	FVCQSFAKNMGLYGE EEEHHHHHHCCCCCC	45.52	-
255	Other	FVCQSFAKNMGLYGE EEEHHHHHHCCCCCC	45.52	-
385	Phosphorylation	FSANGRISMAGLNNS EECCCEEEECCCCCC	10.96	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of AATC_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of AATC_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of AATC_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
ELP3_SCHPO	elp3	genetic	19547744

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of AATC_SCHPO

Related Literatures of Post-Translational Modification