| UniProt ID | BDC1_SCHPO | |
|---|---|---|
| UniProt AC | O74350 | |
| Protein Name | Bromodomain-containing protein 1 | |
| Gene Name | bdc1 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 299 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair.. | |
| Protein Sequence | MNIAQEVAVLQYLDIQQENPNAPNEELFNRTAESSLLLEPIEQDQLKDLVEEWMHDSNKSDSKLLSNQVSQNDNDARKNLRKRLRNDVLKDLAEEIQGCEKKLESLYEEVAKAKAKAVEDQLALEEADKEAKKAKTEAPVEAANKSLRSRKKTPEIAAPANIEPEVAPTTKTPKKRAALSNEEKQSLKKFQSAMLPMLDNISNHRFGAPFSHPVNRKEAPDYDSLVYKPQDLRTLKNMIKEGNITEVDELYREVLRIFANCKMYNGSDPANAMSIWGDECFRYTEELFDIYRQASTRSQ | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 153 | Phosphorylation | SLRSRKKTPEIAAPA HHHHCCCCCCCCCCC | 29.23 | 28889911 | |
| 169 | Phosphorylation | IEPEVAPTTKTPKKR CCCCCCCCCCCHHHH | 31.05 | 29996109 | |
| 172 | Phosphorylation | EVAPTTKTPKKRAAL CCCCCCCCHHHHHCC | 37.94 | 29996109 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of BDC1_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of BDC1_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of BDC1_SCHPO !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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