| UniProt ID | HIF2_SCHPO | |
|---|---|---|
| UniProt AC | O74845 | |
| Protein Name | Set3 complex subunit hif2 | |
| Gene Name | hif2 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 564 | |
| Subcellular Localization | Cytoplasm . Nucleus . | |
| Protein Description | Component of the set3 histone deacetylase complex which is involved in chromatin remodeling and transcription regulation, such as repression of the sporulation gene program.. | |
| Protein Sequence | MDTNQVNYIIWRYLKECGYSHTKFAFERETGIQNLDKQWGSTCQVGALVEILQKGLQYVELEKHYVDNHSSNEEASKTSIDGESLVNENPCKLPFYLTVPHICETTLTKADSTNGFCEHNNSNDHQLKILQDKGSGSPSSPVMPFKDKIEKRDIDITMADESNVEKDPARPIAVYNSSPVTEITEIKQVTFTGGEDIKSDFFKVIPTKHPVTCADWRPLLQENYHVYEFSIGMTNATLASVSICEEQNDFKAKTDYCLQSSFDNQDITGVAWNNSGSFLAYAFFSGVIEIYDSHGSQILSFHNNKGPVLSLKWSGTDTYLAAGSADGTITLFDQLKQTQYSIDTLASSVLDIEWISFDEFVTSDVEGSLRVYKVDGKAPVSTVSHAHDNSIVALRYNLRISLLLTASSDTTVKLWSRGDAGAFECLHVFSFSSPVNCIDWNLREGTPILAVASNSIVSMYNAISLQQLAVFMRHTAPVSALSFSHNGRYLATGDTSGGVCIWSCKTAKLFKELGSDNSELIAVTNVLPEEQVNFLRWSFDDKDLLIGKQKKEIICCCDFLHDSL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 71 | Phosphorylation | HYVDNHSSNEEASKT HCCCCCCCCCCHHCC | 29996109 | ||
| 112 | Phosphorylation | TTLTKADSTNGFCEH EECCCCCCCCCCCCC | 25720772 | ||
| 135 | Phosphorylation | KILQDKGSGSPSSPV EEEEECCCCCCCCCC | 24763107 | ||
| 137 | Phosphorylation | LQDKGSGSPSSPVMP EEECCCCCCCCCCCC | 28889911 | ||
| 139 | Phosphorylation | DKGSGSPSSPVMPFK ECCCCCCCCCCCCCC | 28889911 | ||
| 140 | Phosphorylation | KGSGSPSSPVMPFKD CCCCCCCCCCCCCCH | 28889911 | ||
| 175 | Phosphorylation | PARPIAVYNSSPVTE CCCCEEEEECCCCCE | 24763107 | ||
| 177 | Phosphorylation | RPIAVYNSSPVTEIT CCEEEEECCCCCEEE | 21712547 | ||
| 178 | Phosphorylation | PIAVYNSSPVTEITE CEEEEECCCCCEEEE | 24763107 | ||
| 181 | Phosphorylation | VYNSSPVTEITEIKQ EEECCCCCEEEEEEE | 21712547 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HIF2_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HIF2_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HIF2_SCHPO !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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