HIF2_SCHPO - dbPTM
HIF2_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID HIF2_SCHPO
UniProt AC O74845
Protein Name Set3 complex subunit hif2
Gene Name hif2
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 564
Subcellular Localization Cytoplasm . Nucleus .
Protein Description Component of the set3 histone deacetylase complex which is involved in chromatin remodeling and transcription regulation, such as repression of the sporulation gene program..
Protein Sequence MDTNQVNYIIWRYLKECGYSHTKFAFERETGIQNLDKQWGSTCQVGALVEILQKGLQYVELEKHYVDNHSSNEEASKTSIDGESLVNENPCKLPFYLTVPHICETTLTKADSTNGFCEHNNSNDHQLKILQDKGSGSPSSPVMPFKDKIEKRDIDITMADESNVEKDPARPIAVYNSSPVTEITEIKQVTFTGGEDIKSDFFKVIPTKHPVTCADWRPLLQENYHVYEFSIGMTNATLASVSICEEQNDFKAKTDYCLQSSFDNQDITGVAWNNSGSFLAYAFFSGVIEIYDSHGSQILSFHNNKGPVLSLKWSGTDTYLAAGSADGTITLFDQLKQTQYSIDTLASSVLDIEWISFDEFVTSDVEGSLRVYKVDGKAPVSTVSHAHDNSIVALRYNLRISLLLTASSDTTVKLWSRGDAGAFECLHVFSFSSPVNCIDWNLREGTPILAVASNSIVSMYNAISLQQLAVFMRHTAPVSALSFSHNGRYLATGDTSGGVCIWSCKTAKLFKELGSDNSELIAVTNVLPEEQVNFLRWSFDDKDLLIGKQKKEIICCCDFLHDSL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
71PhosphorylationHYVDNHSSNEEASKT
HCCCCCCCCCCHHCC
29996109
112PhosphorylationTTLTKADSTNGFCEH
EECCCCCCCCCCCCC
25720772
135PhosphorylationKILQDKGSGSPSSPV
EEEEECCCCCCCCCC
24763107
137PhosphorylationLQDKGSGSPSSPVMP
EEECCCCCCCCCCCC
28889911
139PhosphorylationDKGSGSPSSPVMPFK
ECCCCCCCCCCCCCC
28889911
140PhosphorylationKGSGSPSSPVMPFKD
CCCCCCCCCCCCCCH
28889911
175PhosphorylationPARPIAVYNSSPVTE
CCCCEEEEECCCCCE
24763107
177PhosphorylationRPIAVYNSSPVTEIT
CCEEEEECCCCCEEE
21712547
178PhosphorylationPIAVYNSSPVTEITE
CEEEEECCCCCEEEE
24763107
181PhosphorylationVYNSSPVTEITEIKQ
EEECCCCCEEEEEEE
21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of HIF2_SCHPO !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of HIF2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of HIF2_SCHPO !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
RPA12_SCHPOrpa12genetic
18818364
CAF1_SCHPOcaf1genetic
18818364
2AD1_SCHPOpar1genetic
18818364
AAKB_SCHPOamk2genetic
18818364
ARP6_SCHPOarp6genetic
18818364
SWC5_SCHPOswc5genetic
18818364
PHD1_SCHPOhos2physical
22559741
TPP1_SCHPOtpp1genetic
22681890
RYH1_SCHPOryh1genetic
22681890
NSE6_SCHPOnse6genetic
22681890
WTF16_SCHPOwtf16genetic
22681890
REB1_SCHPOreb1genetic
22681890
VTS1_SCHPOSPBC13E7.03cgenetic
22681890
ERI1_SCHPOeri1genetic
22681890
BQT4_SCHPObqt4genetic
22681890
BDC1_SCHPObdc1genetic
22681890
6PGL_SCHPOSPCC16C4.10genetic
22681890
YCGK_SCHPOSPCC16C4.20cgenetic
22681890
ARP6_SCHPOarp6genetic
22681890
PDX1_SCHPOsnz1genetic
22681890
DBR1_SCHPOdbr1genetic
22681890
YIW4_SCHPOSPAC694.04cgenetic
22681890
DEP1_SCHPOdep1genetic
22681890
VIP1_SCHPOasp1genetic
22681890
ARP8_SCHPOarp8genetic
22681890
CCQ1_SCHPOccq1genetic
22681890
WTF21_SCHPOwtf21genetic
22681890
YIQ4_SCHPOSPAC824.04genetic
22681890
CLR4_SCHPOclr4genetic
22681890
YF98_SCHPOnht10genetic
22681890
DAD1_SCHPOdad1genetic
22681890
GYP1_SCHPOgyp1genetic
22681890
GIT3_SCHPOgit3genetic
22681890
YNS7_SCHPOSPBC18H10.07genetic
22681890
NCPR_SCHPOccr1genetic
22681890
YAQD_SCHPOSPAC18G6.13genetic
22681890
PAB2_SCHPOpab2genetic
22681890
ARP42_SCHPOarp42genetic
22681890
SWC3_SCHPOswc3genetic
22681890
NAA35_SCHPOmak10genetic
22681890
YC9F_SCHPOSPCC584.15cgenetic
22681890
ASH2_SCHPOash2genetic
22681890
HIS2_SCHPOhis7genetic
22681890
GBB_SCHPOgit5genetic
22681890
GPA2_SCHPOgpa2genetic
22681890
YEEB_SCHPOSPAC19A8.11cgenetic
22681890
APQ12_SCHPOapq12genetic
22681890
ING2_SCHPOpng2genetic
22681890
YE98_SCHPOerp2genetic
22681890
SNT2_SCHPOsnt2genetic
22681890
MMS19_SCHPOmms19genetic
22681890
LIZ1_SCHPOliz1genetic
22681890
YO48_SCHPOSPBC36B7.08cgenetic
22681890
AROG_SCHPOSPAP8A3.07cgenetic
22681890
YLP3_SCHPOred1genetic
22681890
ELP1_SCHPOelp1genetic
22681890
CLR3_SCHPOclr3genetic
22681890
YIU1_SCHPOsaf5genetic
22681890
YE87_SCHPOSPAC9G1.07genetic
22681890
CTK3_SCHPOlsg1genetic
22681890
ERD11_SCHPOerd1genetic
22681890
ASK1_SCHPOask1genetic
22681890
YI75_SCHPOSPAC977.05cgenetic
22681890
SAT1_SCHPOsat1genetic
22681890
FFT3_SCHPOfft3genetic
22681890
DAD2_SCHPOdad2genetic
22681890
YA99_SCHPOSPAC13G6.09genetic
22681890
H2AZ_SCHPOpht1genetic
22681890
IWR1_SCHPOiwr1genetic
22681890
IMA2_SCHPOimp1genetic
22681890
MCL1_SCHPOmcl1genetic
22681890
UGE1_SCHPOuge1genetic
22681890
TCG1_SCHPOtcg1genetic
22681890
HIF2_SCHPOhif2physical
26771498

Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of HIF2_SCHPO

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Related Literatures of Post-Translational Modification

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