dbPTM

YF98_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YF98_SCHPO
UniProt AC	O42648
Protein Name	HMG box-containing protein C10F6.08c
Gene Name	SPAC10F6.08c
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	341
Subcellular Localization	Nucleus .
Protein Description
Protein Sequence	MENPPYHVSISKSEEIKYRQKCKDLKARIQEIQKGNQELLSKYEVIRRAVKRGRLERAILMEQLELQSEAKSREFGQRSEPSPPPPPEGIKIKISTKGAGNPSAKKLKISTEETSDTNVALNNTSEISHKSSNNSQPKDASVNDTDADFEQQNQVVQSKDEKITNTDPIPSPIITNLKTESSKSSGAKKATSNAKITDTMLFNHFSSIQKPKLKAEGSTLKGQALKKTLEDTWNNLTEEEKKPYHEGLLAAREKAREARRRRSAQNSAKLEKEKAKEKQKDKDQEQDTVSDKNQIDEIEKGQKEVDEEPVSEPTTSPILPPKNQEPIRMGGFTVVNRSSNA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
72	Phosphorylation	ELQSEAKSREFGQRS HHHHHHHHHHCCCCC	44.05	21712547
79	Phosphorylation	SREFGQRSEPSPPPP HHHCCCCCCCCCCCC	46.07	29996109
82	Phosphorylation	FGQRSEPSPPPPPEG CCCCCCCCCCCCCCC	46.09	28889911
114	Phosphorylation	LKISTEETSDTNVAL CEEECCCCCCCCEEC	26.18	21712547
115	Phosphorylation	KISTEETSDTNVALN EEECCCCCCCCEECC	45.80	29996109
117	Phosphorylation	STEETSDTNVALNNT ECCCCCCCCEECCCC	31.21	25720772
141	Phosphorylation	NSQPKDASVNDTDAD CCCCCCCCCCCCCCC	31.42	25720772
166	Phosphorylation	KDEKITNTDPIPSPI CCCCCCCCCCCCCCC	34.21	29996109
171	Phosphorylation	TNTDPIPSPIITNLK CCCCCCCCCCCCCCC	29.47	28889911
311	Phosphorylation	EVDEEPVSEPTTSPI CCCCCCCCCCCCCCC	48.88	29996109
314	Phosphorylation	EEPVSEPTTSPILPP CCCCCCCCCCCCCCC	35.54	28889911
315	Phosphorylation	EPVSEPTTSPILPPK CCCCCCCCCCCCCCC	43.13	28889911
316	Phosphorylation	PVSEPTTSPILPPKN CCCCCCCCCCCCCCC	16.66	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YF98_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YF98_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YF98_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
YF98_SCHPO	nht10	physical	26771498

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YF98_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-314; THR-315 ANDSER-316, AND MASS SPECTROMETRY.	18257517 [Abstract]