VTS1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: VTS1_SCHPO
• UniProt AC: Q9P6R7
• Protein Name: Protein vts1
• Gene Name: SPBC13E7.03c
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 713
• Subcellular Localization: Cytoplasm.
• Protein Description: RNA-binding protein involved in post-transcriptional regulation through transcript degradation. May be involved in vacuolar protein transport (By similarity)..
• Protein Sequence: MEVVEGRRKTCLDVVDSPSSRQKQTIAVSLVDGKNYPTRFLNSRTIDKLKQELNTSNLSTGEMSTNETLKNAQEVAGKLLSEENEDSISEHFDEYLGADKPGISFLTRLKTLESWFQSLSLQDRLTTLRTLLHHLPSQEISTLLSSSLTSSPSNSGLSLDKSLPSSPKGDSPSLSSSLPSLTTKSNLSGNLNMVTPASTQGPAFSSKHGFSNALSTASPIPVRTSSVSSTYLTQDREASSKNCLSKALAFSSIEPPASSASTSPRNTPTPSNNGTSINANVTSSLTSNSTGKTSKTTDLLIAASKKSLPSNSTPSKPNTSFFETPHNNIWDSRDRGAFSAPPAPFFPLGFSPHLNDESSRSRWSNISYSPPPPPPPPELLNHSPKSRPLGDKPYLFYRNNQIGPRTRTEGRSSITEGKPFLSSSLRFEHVPSANDLNSVVNARVEKSTGQPSTPLNRQHYFNELPHSTTPVTLPSLIHGSEIDRRRSGFCLNNFNSTPPFQPYHYEIGSGLPQQMHATNTILTNPIDPNSNISTPVGMHLCTLPYTYQPFSSVEKIETPPNNSKNQTYRRSSRGSNKTRKSISHSKNTDKHVGNELPQDIPSWLRSLRLHKYTNNLKDTDWDALVSLSDLDLQNRGIMALGARRKLLKSFQEVAPLVSSKKMNENLKAAKNQSSESLTSFKGHTDSEDLPSGSMSNEISSNSTKQDVSSSSMD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
10	Phosphorylation	VVEGRRKTCLDVVDS CCCCCCCCHHEECCC	19.25	29996109
17	Phosphorylation	TCLDVVDSPSSRQKQ CHHEECCCCCCCCCE	18.31	21712547
20	Phosphorylation	DVVDSPSSRQKQTIA EECCCCCCCCCEEEE	41.96	29996109
25	Phosphorylation	PSSRQKQTIAVSLVD CCCCCCEEEEEEECC	20.24	28889911
38	Phosphorylation	VDGKNYPTRFLNSRT CCCCCCCCCHHCHHH	24.56	28889911
81	Phosphorylation	EVAGKLLSEENEDSI HHHHHHHCCCCCCHH	53.99	29996109
87	Phosphorylation	LSEENEDSISEHFDE HCCCCCCHHHHHHHH	23.10	29996109
89	Phosphorylation	EENEDSISEHFDEYL CCCCCHHHHHHHHHH	29.04	29996109
158	Phosphorylation	SPSNSGLSLDKSLPS CCCCCCCCCCCCCCC	37.74	29996109
162	Phosphorylation	SGLSLDKSLPSSPKG CCCCCCCCCCCCCCC	45.22	24763107
165	Phosphorylation	SLDKSLPSSPKGDSP CCCCCCCCCCCCCCC	65.65	24763107
166	Phosphorylation	LDKSLPSSPKGDSPS CCCCCCCCCCCCCCC	28.79	21712547
171	Phosphorylation	PSSPKGDSPSLSSSL CCCCCCCCCCHHHCC	25.67	28889911
173	Phosphorylation	SPKGDSPSLSSSLPS CCCCCCCCHHHCCCC	44.85	21712547
175	Phosphorylation	KGDSPSLSSSLPSLT CCCCCCHHHCCCCCC	23.40	24763107
177	Phosphorylation	DSPSLSSSLPSLTTK CCCCHHHCCCCCCCC	40.71	21712547
180	Phosphorylation	SLSSSLPSLTTKSNL CHHHCCCCCCCCCCC	43.57	21712547
211	Phosphorylation	FSSKHGFSNALSTAS CCCCCCCCHHHCCCC	26.28	29996109
215	Phosphorylation	HGFSNALSTASPIPV CCCCHHHCCCCCCCC	21.37	21712547
216	Phosphorylation	GFSNALSTASPIPVR CCCHHHCCCCCCCCC	31.82	25720772
218	Phosphorylation	SNALSTASPIPVRTS CHHHCCCCCCCCCCC	24.37	25720772
224	Phosphorylation	ASPIPVRTSSVSSTY CCCCCCCCCCCCCEE	26.11	25720772
226	Phosphorylation	PIPVRTSSVSSTYLT CCCCCCCCCCCEECC	25.96	21712547
252	Phosphorylation	SKALAFSSIEPPASS HHHHHHHCCCCCCCC	25.23	29996109
258	Phosphorylation	SSIEPPASSASTSPR HCCCCCCCCCCCCCC	32.01	25720772
259	Phosphorylation	SIEPPASSASTSPRN CCCCCCCCCCCCCCC	28.48	29996109
261	Phosphorylation	EPPASSASTSPRNTP CCCCCCCCCCCCCCC	31.22	28889911
262	Phosphorylation	PPASSASTSPRNTPT CCCCCCCCCCCCCCC	42.33	29996109
263	Phosphorylation	PASSASTSPRNTPTP CCCCCCCCCCCCCCC	21.26	28889911
267	Phosphorylation	ASTSPRNTPTPSNNG CCCCCCCCCCCCCCC	29.80	25720772
293	Phosphorylation	TSNSTGKTSKTTDLL CCCCCCCCCCHHHHH	36.48	25720772
294	Phosphorylation	SNSTGKTSKTTDLLI CCCCCCCCCHHHHHH	31.33	25720772
304	Phosphorylation	TDLLIAASKKSLPSN HHHHHHHHCCCCCCC	31.43	25720772
312	Phosphorylation	KKSLPSNSTPSKPNT CCCCCCCCCCCCCCC	46.14	29996109
315	Phosphorylation	LPSNSTPSKPNTSFF CCCCCCCCCCCCCCC	61.91	29996109
339	Phosphorylation	SRDRGAFSAPPAPFF CCCCCCCCCCCCCCC	39.05	29996109
351	Phosphorylation	PFFPLGFSPHLNDES CCCCCCCCCCCCCCC	15.04	25720772
358	Phosphorylation	SPHLNDESSRSRWSN CCCCCCCCCCCCCCC	33.64	29996109
369	Phosphorylation	RWSNISYSPPPPPPP CCCCCCCCCCCCCCC	24.92	29996109
383	Phosphorylation	PPELLNHSPKSRPLG CHHHCCCCCCCCCCC	32.71	29996109
412	Phosphorylation	RTRTEGRSSITEGKP CCCCCCCCCCCCCCC	36.63	29996109
413	Phosphorylation	TRTEGRSSITEGKPF CCCCCCCCCCCCCCC	31.97	29996109
415	Phosphorylation	TEGRSSITEGKPFLS CCCCCCCCCCCCCCC	40.40	29996109
452	Phosphorylation	EKSTGQPSTPLNRQH HHCCCCCCCCCCHHH	34.47	29996109
453	Phosphorylation	KSTGQPSTPLNRQHY HCCCCCCCCCCHHHC	38.18	29996109
468	Phosphorylation	FNELPHSTTPVTLPS CCCCCCCCCCCCCHH	31.89	29996109
469	Phosphorylation	NELPHSTTPVTLPSL CCCCCCCCCCCCHHH	20.83	29996109
558	Phosphorylation	SSVEKIETPPNNSKN CCCEECCCCCCCCCC	47.74	29996109
673	Phosphorylation	LKAAKNQSSESLTSF HHHHHHCCCHHHHHC	45.53	28889911
674	Phosphorylation	KAAKNQSSESLTSFK HHHHHCCCHHHHHCC	22.80	25720772
676	Phosphorylation	AKNQSSESLTSFKGH HHHCCCHHHHHCCCC	38.61	28889911
678	Phosphorylation	NQSSESLTSFKGHTD HCCCHHHHHCCCCCC	41.20	29996109
679	Phosphorylation	QSSESLTSFKGHTDS CCCHHHHHCCCCCCC	30.19	24763107
684	Phosphorylation	LTSFKGHTDSEDLPS HHHCCCCCCCCCCCC	50.30	21712547
686	Phosphorylation	SFKGHTDSEDLPSGS HCCCCCCCCCCCCCC	33.88	21712547

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of VTS1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of VTS1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of VTS1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
YH7G_SCHPO	SPBC16G5.16	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-673, AND MASSSPECTROMETRY.
PubMed: 18257517