| UniProt ID | HRP3_SCHPO | |
|---|---|---|
| UniProt AC | O14139 | |
| Protein Name | Chromodomain helicase hrp3 | |
| Gene Name | hrp3 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 1388 | |
| Subcellular Localization | Nucleus . | |
| Protein Description | Involved in heterochromatin silencing. Required for transcriptional repression at the silence loci of mat3, where it has a direct role as a chromatin remodeling factor.. | |
| Protein Sequence | MSTSAIALALSSSKAIEQLDHVQTETPNLKQEMSESPSNSGVASKRKLQSTEWLDPELYGLRRSGRTRSNPGRYVDTDDQEDVFPSKHRKGTRNGSSFSRHRTIRDLDDEAESVTSEESESDDSSYGGTPKKRSRQKKSNTYVQDEIRFSSRNSKGVNYNEDAYFESFEEEEEEEMYEYATEVSEEPEDTRAIDVVLDHRLIEGHDGSTPSEDYEFLIKWVNFSHLHCTWEPYNNISMIRGSKKVDNHIKQVILLDREIREDPTTTREDIEAMDIEKERKRENYEEYKQVDRIVAKHLNSDGSVEYLVKWKQLLYDFCTWEASSIIEPIAATEIQAFQEREESALSPSRGTNYGNSRPKYRKLEQQPSYITGGELRDFQLTGVNWMAYLWHKNENGILADEMGLGKTVQTVAFLSYLAHSLRQHGPFLVVVPLSTVPAWQETLALWASDMNCISYLGNTTSRQVIRDYEFYVDGTQKIKFNLLLTTYEYVLKDRSVLSNIKWQYMAIDEAHRLKNSESSLYEALSQFKNSNRLLITGTPLQNNIRELAALVDFLMPGKFEIREEINLEAPDEEQEAYIRSLQEHLQPYILRRLKKDVEKSLPSKSERILRVELSDLQMYWYKNILTRNYRVLTQSISSGSQISLLNIVVELKKASNHPYLFDGVEESWMQKINSQGRRDEVLKGLIMNSGKMVLLDKLLSRLRRDGHRVLIFSQMVRMLDILGDYLSLRGYPHQRLDGTVPAAVRRTSIDHFNAPNSPDFVFLLSTRAGGLGINLMTADTVIIFDSDWNPQADLQAMARAHRIGQKNHVMVYRLLSKDTIEEDVLERARRKMILEYAIISLGVTDKQKNSKNDKFSAEELSAILKFGASNMFKAENNQKKLEDMNLDEILEHAEDHDTSNDVGGASMGGEEFLKQFEVTDYKADVSWDDIIPLTEREKFEEEDRLREEEEALKQEIELSSRRGNRPYPSSAVESPSYSGTSERKSKKQMLKDEVLLEKEIRLLYRAMIRYGSLEHRYNDIVKYADLTTQDAHVIKKIAADLVTASRKAVSAAEKDLSNDQSNNKSSRKALLITFKGVKNINAETLVQRLNDLDILYDAMPTSGYSNFQIPMHVRSVHGWSCQWGPREDSMLLSGICKHGFGAWLEIRDDPELKMKDKIFLEDTKQTDNSVPKDKENKEKKVPSAVHLVRRGEYLLSALREHHQNFGIKSSPAISTNGKTQPKKQTANRRQSGKPNVKSAQKIESATRTPSPAISESRKKPSSKDTKIETPSREQSRSQTASPVKSEKDDGNVSLNAEQKARCKELMYPVRKHMKRLRKDSSGLGRAELVKLLTECLTTIGKHIEKTVNDTPSEEKATVRKNLWMFACYFWPKEEVKYTSLISMYEKMK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 34 | Phosphorylation | PNLKQEMSESPSNSG CCHHHHHCCCCCCCC | 33.88 | 29996109 | |
| 36 | Phosphorylation | LKQEMSESPSNSGVA HHHHHCCCCCCCCCC | 26.73 | 29996109 | |
| 38 | Phosphorylation | QEMSESPSNSGVASK HHHCCCCCCCCCCCH | 53.56 | 29996109 | |
| 77 | Phosphorylation | NPGRYVDTDDQEDVF CCCCCCCCCCCCCCC | 31.28 | 28889911 | |
| 926 | Phosphorylation | TDYKADVSWDDIIPL CCCCCCCCHHHCCCC | 25.90 | 24763107 | |
| 934 | Phosphorylation | WDDIIPLTEREKFEE HHHCCCCCHHHHHHH | 27.87 | 21712547 | |
| 967 | Phosphorylation | SRRGNRPYPSSAVES HCCCCCCCCCCCCCC | 16.71 | 29996109 | |
| 969 | Phosphorylation | RGNRPYPSSAVESPS CCCCCCCCCCCCCCC | 25.70 | 25720772 | |
| 970 | Phosphorylation | GNRPYPSSAVESPSY CCCCCCCCCCCCCCC | 31.65 | 25720772 | |
| 974 | Phosphorylation | YPSSAVESPSYSGTS CCCCCCCCCCCCCCC | 16.73 | 29996109 | |
| 976 | Phosphorylation | SSAVESPSYSGTSER CCCCCCCCCCCCCCC | 41.01 | 29996109 | |
| 1210 | Phosphorylation | QNFGIKSSPAISTNG HHCCCCCCCCCCCCC | 17.22 | 27738172 | |
| 1238 | Phosphorylation | SGKPNVKSAQKIESA CCCCCHHHHHHHHHH | 31.48 | 25720772 | |
| 1244 | Phosphorylation | KSAQKIESATRTPSP HHHHHHHHHCCCCCC | 38.11 | 24763107 | |
| 1246 | Phosphorylation | AQKIESATRTPSPAI HHHHHHHCCCCCCCC | 44.34 | 29996109 | |
| 1248 | Phosphorylation | KIESATRTPSPAISE HHHHHCCCCCCCCCC | 24.62 | 29996109 | |
| 1250 | Phosphorylation | ESATRTPSPAISESR HHHCCCCCCCCCCCC | 26.76 | 28889911 | |
| 1254 | Phosphorylation | RTPSPAISESRKKPS CCCCCCCCCCCCCCC | 31.46 | 25720772 | |
| 1256 | Phosphorylation | PSPAISESRKKPSSK CCCCCCCCCCCCCCC | 42.48 | 25720772 | |
| 1269 | Phosphorylation | SKDTKIETPSREQSR CCCCCCCCCCHHHHC | 30.00 | 21712547 | |
| 1271 | Phosphorylation | DTKIETPSREQSRSQ CCCCCCCCHHHHCCC | 56.73 | 21712547 | |
| 1275 | Phosphorylation | ETPSREQSRSQTASP CCCCHHHHCCCCCCC | 29.19 | 21712547 | |
| 1277 | Phosphorylation | PSREQSRSQTASPVK CCHHHHCCCCCCCCC | 36.81 | 21712547 | |
| 1279 | Phosphorylation | REQSRSQTASPVKSE HHHHCCCCCCCCCCC | 30.28 | 25720772 | |
| 1281 | Phosphorylation | QSRSQTASPVKSEKD HHCCCCCCCCCCCCC | 33.35 | 24763107 | |
| 1285 | Phosphorylation | QTASPVKSEKDDGNV CCCCCCCCCCCCCCC | 50.54 | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of HRP3_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of HRP3_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of HRP3_SCHPO !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
