dbPTM

MIC60_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	MIC60_SCHPO
UniProt AC	O59725
Protein Name	MICOS complex subunit mic60
Gene Name	mic60
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	550
Subcellular Localization	Mitochondrion inner membrane Single-pass membrane protein.
Protein Description	Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity)..
Protein Sequence	MNRQLRTVKSCFSLQKTHQYRSFWIQSSLRALPPDVKQNKTEPIPFVPKPEEGSSNKSNSSKFRKRFLLLFLLGITGYSCSVVYCFKDPNFYDYFAEHTPFGKQVLYNVEQSWIGYKYLGGNRIKVDDSSPKLKQNSNNISKKQNSSRNDDTKVKKDTTIERPESLVVEIVDLPSEVTKDTAEESVWKDIGLDQETGLSVTAIPIITETLDHAHEQEIKDQSLRFESSLNEANELHGKLSKIQQEQEHLFEQRLREKVSEMESKLEALLIARDEKWQSAFESEKLRLQKLHEARLQQELFKLASVFESKLKNELTEQAITLEKLHLQSIKAQVEQERGSRLGRLQELRNSFQQLQELVRVVLHENGRVTRLVDVSNTLDDLNKDMRFHKLSEVRQHVNTLKEATKDDELAALASRVIEKIVDSGPILDKEELQTKFDTLSKEIYKTCFLTTESGFFGHLKSIILSQLPAAVFKSPDIVSVKKTLEDARSHLLKDDLDGSVRALLSLSQWPRALSRDWINACRRRMELQQAIEIIKASATLSSQLEDAQQA

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of MIC60_SCHPO !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of MIC60_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of MIC60_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of MIC60_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of MIC60_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of MIC60_SCHPO

Related Literatures of Post-Translational Modification