dbPTM

VPS1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	VPS1_SCHPO
UniProt AC	Q9URZ5
Protein Name	Vacuolar protein sorting-associated protein 1
Gene Name	vps1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	678
Subcellular Localization
Protein Description
Protein Sequence	MDPSLIKVVNQLQEAFSTVGVQNLIDLPQITVVRSQSSGKSSVLENIVGRDFLPRGTGIVTRRPLVLQLINRPSASGKNEETTTDSDGKDQNNSSEWGEFLHLPGQKFFEFEKIREEIVRETEEKTGKNVGISSVPIYLRIYSPHVLTLTLVDLPGLTKVPVGDQPRDIEKQIREMVLKYISKNNAIILAVNAANTDLANSDGLKLAREVDPEGLRTIGVLTKVDLMDKGTDVVDILAGRVIPLRLGYVPVINRGQKDIEGKKSIRIALEAERNFFETHPSYGSKAQYCGTPFLARKLNMILMHHIRNTLPEIKVRINAALAKYQAELHSLGDTPVGDNSSIVLNLITDFCNEYRTVVDGRSEELSATELSGGARIAFVFHEIFSNGIQAIDPFDEVKDSDIRTILYNSSGPSPSLFMGTAAFEVIVKQQIKRLEDPSLKCVSLIYDELVRILNQLLQRPIFKRYPLLKDEFYKVVIGFFRKCMQPTNTLVMDMVAMEGSYINTVHPDFLSGHQAMAIVQSQNSKPIPVDPKTGKALTNNPVPPVETSSSSGQNFFGSFFGSKNKKRLAAMEPPPPVLRASTTLSDREKTDTEVIKLLIMSYFNIVKRTLADMVPKSISLKMIKYSKEHIQHELLEQLYKSQAFDKLLQESEVTVQRRKECEQMVESLLQASEIVSNV

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
86	Phosphorylation	NEETTTDSDGKDQNN CCCCCCCCCCCCCCC	46.28	21712547
94	Phosphorylation	DGKDQNNSSEWGEFL CCCCCCCCCCHHHHH	36.86	21712547
549	Phosphorylation	VPPVETSSSSGQNFF CCCCCCCCCCCCCCH	35.62	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of VPS1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of VPS1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of VPS1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
DNM1_SCHPO	dnm1	genetic	18088324
DNM1_SCHPO	dnm1	genetic	20070859
ATG1_SCHPO	atg1	genetic	20070859
ATG2_SCHPO	atg2	genetic	20070859
ATG4_SCHPO	atg4	genetic	20070859
ATG7_SCHPO	atg7	genetic	20070859
ATG8_SCHPO	atg8	genetic	20070859
ENG2_SCHPO	eng2	genetic	25040903

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of VPS1_SCHPO

Related Literatures of Post-Translational Modification