DNM1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: DNM1_SCHPO
• UniProt AC: Q09748
• Protein Name: Dynamin-related protein dnm1
• Gene Name: dnm1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 781
• Subcellular Localization: Cytoplasm . Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side. Localizes at sites of mitochondrial constriction.
• Protein Description: Microtubule-associated force-producing protein that mediates mitochondrial fission during interphasic growth and at cell division. Fission of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. With vps1, acts redundantly in peroxisome biogenesis, which is under cell cycle control..
• Protein Sequence: MEQLIPLVNQLQDLVYNTIGSDFLDLPSIVVVGSQSCGKSSVLENIVGKDFLPRGTGIVTRRPLILQLINLKRKTKNNHDEESTSDNNSEETSAAGETGSLEGIEEDSDEIEDYAEFLHIPDTKFTDMNKVRAEIENETLRVAGANKGINKLPINLKIYSTRVLNLTLIDLPGLTKIPVGDQPTDIEAQTRSLIMEYISRPNSIILAVSPANFDIVNSEGLKLARSVDPKGKRTIGVLTKLDLMDQGTNAMDILSGRVYPLKLGFVATVNRSQSDIVSHKSMRDALQSERSFFEHHPAYRTIKDRCGTPYLAKTLSNLLVSHIRERLPDIKARLSTLISQTQQQLNNYGDFKLSDQSQRGIILLQAMNRFANTFIASIDGNSSNIPTKELSGGARLYSIFNNVFTTALNSIDPLQNLSTVDIRTAILNSTGSRATLFLSEMAFDILVKPQLNLLAAPCHQCVELVYEELMKICHYSGDSDISHFPKLQTALVETVSDLLRENLTPTYSFVESLIAIQSAYINTNHPDFLGVQGAMAVVLSRKEQNRLMLSQENDEPISSALDTVKPDGIELYSSDPDTSVKSITNKATNEITTLKSDDSAKMQPLDVLASKRYNNAFSTETAERKTFLSYVFGANNATRKAMSIDKSSSYPLNDSLSGGDTNHKNNHPLKMTDLSNEVETMALEDMSEREEVEVDLIKELITSYFNLTRKIIIDQVPKVIMHLLVNASKDAIQNRLVSKLYREDFFDTLLIEDENVKSEREKCERLLSVYNQANKIISTVF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
578	Phosphorylation	LYSSDPDTSVKSITN EECCCCCCCHHHHHC		21712547
579	Phosphorylation	YSSDPDTSVKSITNK ECCCCCCCHHHHHCC		29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of DNM1_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of DNM1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of DNM1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VPS1_SCHPO	vps1	genetic	18088324
SERB_SCHPO	ser2	genetic	18818364
POB3_SCHPO	pob3	genetic	18818364
HIR1_SCHPO	hip1	genetic	18818364
RYH1_SCHPO	ryh1	genetic	22681890
DUR33_SCHPO	SPAC869.03c	genetic	22681890
YAJ1_SCHPO	gto2	genetic	22681890
CLR2_SCHPO	clr2	genetic	22681890
GPDM_SCHPO	gut2	genetic	22681890
SND1_SCHPO	snd1	genetic	22681890
TIP1_SCHPO	tip1	genetic	22681890
MCL1_SCHPO	mcl1	genetic	22681890
YBD1_SCHPO	SPBC16C6.01c	genetic	22681890
DNM1_SCHPO	dnm1	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.