dbPTM

YGZ7_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	YGZ7_SCHPO
UniProt AC	O42976
Protein Name	Uncharacterized membrane protein C20F10.07
Gene Name	SPBC20F10.07
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	764
Subcellular Localization	Membrane Single-pass membrane protein . Localizes to cytoplasmic punctate structures.
Protein Description
Protein Sequence	MKEENGFAGFLNTAVNRLSGVLNDTAPTKSQSLKNGVNNEGNRGFSLFRNPRFMSDEKLSSEASSHSTLGQQQARDGRQSPSKEAPFGEGELKLENFENQENEADEAENEETSYSEQNHTENTEEIAEESRPLERTHSGSNHHEASSTGHLNLPPLENTLSQGSAITAPSRKVSITSSNGVSARLSGYAFANSKRNRDFHRIFKVLPPEDHLIDDYGCALQRDIFLHGRMYLSESHICFNSSIFGWVTNIVIPVTEIVSVEKKSTAVVFPNAIQITTLHARYIFASFISRDTTYQLIIAIWKNTHPFLTTLANGHGVMDASGNHHSGSSNQSINADSSAGSEGVDEGTSTEANDESSEDDDEDNNTDEANEDAQSNVSDESPKGEGSSHSDNVVLSDGNSVKKMNEDGADTSLLSVSEVTSHPPTEWTGSPLAHVLCSDVVNLSVSTVFNLLCGSDTTWIINFFKSEKLTEIKIGKWEKIDDKWNRKVQYIKPVAPPYRQTSCYITDTIQHLDINNYIEILSTTSTPDVPSGTSFVVKTLYALSWAHSSKTKLNISYSVEWSKSSWLKGPIEKGAQEGQASYVKDLLTAFENYKVSPKGRRKKITKHTKKKNKHASETSVAPEKVDNSSIEQSSSFLTKLYTFPFTIITWLMHPTHLLLVVMFSMLVLQWWYMQQILHAELPSTSSRSDSSRDLDFDHIPMDDTAFKLWITSRLDSVERDRDFVYENSDPNLEHGKIKIATDYMERRLKKLKERLRKLEASGYI

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
23	N-linked_Glycosylation	NRLSGVLNDTAPTKS HHHHHHCCCCCCCCC	42.03	-
32	Phosphorylation	TAPTKSQSLKNGVNN CCCCCCHHHCCCCCC	48.69	25720772
55	Phosphorylation	FRNPRFMSDEKLSSE CCCCCCCCCHHHCHH	39.65	25720772
65	Phosphorylation	KLSSEASSHSTLGQQ HHCHHHHHCCHHHHH	28.62	25720772
67	Phosphorylation	SSEASSHSTLGQQQA CHHHHHCCHHHHHHH	27.55	25720772
68	Phosphorylation	SEASSHSTLGQQQAR HHHHHCCHHHHHHHC	29.50	21712547
80	Phosphorylation	QARDGRQSPSKEAPF HHCCCCCCCCCCCCC	29.76	28889911
82	Phosphorylation	RDGRQSPSKEAPFGE CCCCCCCCCCCCCCC	48.66	21712547
118	N-linked_Glycosylation	ETSYSEQNHTENTEE HCCHHCCCCCCCHHH	39.74	-
174	Phosphorylation	TAPSRKVSITSSNGV CCCCCEEEEECCCCC	24.16	29996109
176	Phosphorylation	PSRKVSITSSNGVSA CCCEEEEECCCCCEE	20.70	29996109
177	Phosphorylation	SRKVSITSSNGVSAR CCEEEEECCCCCEEE	21.82	29996109
178	Phosphorylation	RKVSITSSNGVSARL CEEEEECCCCCEEEE	29.02	25720772
182	Phosphorylation	ITSSNGVSARLSGYA EECCCCCEEEEECEE	14.74	25720772
186	Phosphorylation	NGVSARLSGYAFANS CCCEEEEECEEECCC	24.97	25720772
240	N-linked_Glycosylation	SESHICFNSSIFGWV CCCCEEECCHHHHHH	30.36	-
330	N-linked_Glycosylation	NHHSGSSNQSINADS CCCCCCCCCCCCCCC	41.12	-
364	N-linked_Glycosylation	SEDDDEDNNTDEANE CCCCCCCCCCHHHHH	51.78	-
376	N-linked_Glycosylation	ANEDAQSNVSDESPK HHHHHHHHCCCCCCC	25.82	-
387	Phosphorylation	ESPKGEGSSHSDNVV CCCCCCCCCCCCCEE	22.15	21712547
388	Phosphorylation	SPKGEGSSHSDNVVL CCCCCCCCCCCCEEE	37.56	21712547
390	Phosphorylation	KGEGSSHSDNVVLSD CCCCCCCCCCEEECC	32.59	21712547
396	Phosphorylation	HSDNVVLSDGNSVKK CCCCEEECCCCCEEE	31.68	21712547
400	Phosphorylation	VVLSDGNSVKKMNED EEECCCCCEEECCCC	40.62	24763107
442	N-linked_Glycosylation	VLCSDVVNLSVSTVF HHHHHCCCCCHHHHH	26.84	-
554	N-linked_Glycosylation	HSSKTKLNISYSVEW CCCCCEEEEEEEEEE	23.79	-
616	Phosphorylation	KKKNKHASETSVAPE HHCCCCCCCCCCCCH	40.92	21712547
618	Phosphorylation	KNKHASETSVAPEKV CCCCCCCCCCCCHHC	26.46	21712547
619	Phosphorylation	NKHASETSVAPEKVD CCCCCCCCCCCHHCC	16.54	21712547
627	N-linked_Glycosylation	VAPEKVDNSSIEQSS CCCHHCCCCCHHHHH	40.41	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of YGZ7_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of YGZ7_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of YGZ7_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of YGZ7_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of YGZ7_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-80, AND MASSSPECTROMETRY.	18257517 [Abstract]