| UniProt ID | MIT1_SCHPO | |
|---|---|---|
| UniProt AC | Q9P793 | |
| Protein Name | Chromatin remodeling factor mit1 | |
| Gene Name | mit1 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 1418 | |
| Subcellular Localization | Nucleus. Chromosome, centromere. Chromosome, telomere. Associates with major heterochromatin, centromeres, sub-telomeres, rDNA and the mat locus. | |
| Protein Description | Required for proper positioning of nucleosomes at heterochromatic loci and for transcriptional gene silencing (TGS) function of the Snf2/Hdac-containing repressor complex (SHREC).. | |
| Protein Sequence | MPKEDDSLCKIVVRREPLDVLLPYYDASETTVQKILHENDSTLSVKFLAGVEALIKKDELDKYKNGKACLRVWLKHKSRKRYHGYMTSTDKDEEEKNDYLLKSNGSKVLRDSTRTKKFKFGKEFHCALNPSFVSDETASDSATSSSSDTNKKVNRKEHNELSLSHLSFNDTSDFGSSDLSSSEIESTENDNKAPYFSLLYSDGFDFIKFLHVCVCVKCHGREHRSSGKNFVYCDHCSNVYHYDCSPLPSLNKETRNYSQQNGFICPLCSKNSKDVLCNTGFVSGVSSGQDLVIPPSLADRESLSILVNYCKSIRFRCFRCRRVEYFFYLDSNPLSIQRTITHFIKKLVCNECSMHPCDIEEIIAWRTLNSLYPSKATLSNNFVSTSDLSFWSREYFVRSKGKSYLHCFWCSASWLAGISLAKKKNFDGLENASYDATKPIIPVSYTIIDKVWDVQYRSGKNARTAKYKTKKHQLKAISEVTFAFVSWRGLTYYMSNWEPPPKETDRNRWKAWLKGYSDLLECLWIEKAPTASINIDLPFTNLEWHSQPSFIKGGTLMPYQLKGLNWLYLRWYTHHPCILADEMGLGKTVQVISFISVLFYRHKCFPVLVIVPHATVANWERELKKWAPFLQINVLVGSEKNRSLVRDYRLINQKDPKHVSTHVLVISASNVEREISLLRKFQWKVLIVDEGQRLKNDQSSLFYYLSSVKSDFKLLLTGTPLQNNVRELFNLLQFLNPMKINAAELEKRYSIIDTEKVTELHQILKPFFLRRVKSEVLDNFPTKVEVIIPLSMTPVQKGLYKSILSKNLSLLRNITGYANTSSSGGQRTTSLNNILMQLRKTLAHPYIYSPDIEDRNLPYELAMRSLEEASCKFLILRLLVPKLITRGHRILLFSQFIQQLDILEDWFEYKNIAYARFDGASSEMERQSAIDSFNAPNSELSCFLLSTRAGGVGINLASADTVIILDPDFNPHQDMQAIARAHRYGQKKKVLVFVLTTRDSVEEKIIQNAQKKLVLDHLIVESLDQNHNSEKDLESILRHGARALFEEAGDEPSIKYNEYSVELLISEAEKQEDTSTDESDIKSNKFGFFRVWDNKHISSNHYEVKENVLVDEEDVWSVILKQREKDAMLEKTDETTSNRRLRAHHKIHYGEDLNIYDNSDDTDYTVNDRSSPGSPFPIETETISSITDTLSDKQKLKYDSSVNIENLNDESDSQKSADVHFDSILAKSLLATTPKEDEFNKTLSTINLEVANKLTSSEYINDSEMQLIDDPVFYPPYEIIEKNHQLVGRSLSKAVLDNFFLLSSLSDNVRCRCCGIKHLPAHCPLSIVPLEICFLCGTPHFSGRDTCPMLRNKEAIYRLKDSLSKSREPFHIKKQAMARLNSFLQKKEEPTVSSSAKTNELSSKVIIKESIINEAKTL | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of MIT1_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of MIT1_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of MIT1_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of MIT1_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| ASF1_SCHPO | cia1 | genetic | 21211723 | |
| HIR1_SCHPO | hip1 | genetic | 21211723 | |
| HRR1_SCHPO | hrr1 | genetic | 18818364 | |
| JHD1_SCHPO | epe1 | genetic | 18818364 | |
| AGO1_SCHPO | ago1 | genetic | 18818364 | |
| YOI5_SCHPO | SPBC1778.05c | genetic | 22681890 | |
| YIDH_SCHPO | SPAC227.17c | genetic | 22681890 | |
| MCL1_SCHPO | mcl1 | genetic | 22681890 | |
| SEB1_SCHPO | seb1 | physical | 24013500 | |
| CHP2_SCHPO | chp2 | physical | 24662054 | |
| H33_BOVIN | H3F3A | physical | 24662054 | |
| SET2_SCHPO | set2 | genetic | 24662054 | |
| CLR1_SCHPO | clr1 | physical | 27105116 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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