dbPTM

KPR1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	KPR1_SCHPO
UniProt AC	P41831
Protein Name	Ribose-phosphate pyrophosphokinase 1
Gene Name	SPAC4A8.14
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	409
Subcellular Localization	Cytoplasm .
Protein Description	5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases (By similarity)..
Protein Sequence	MKSATIIGGGSHPELLHLISNRLGITPCDVSLKRFANGETSVEIRESVRDKDVFILQSGSSTVNDSLMELLIIISACKGGSAKRITAVMPYFPYSKQSKMRKYRDAITARMVANLLTVAGVDHIITLDLHASQMQGFFTRPVDNLYAEPNIAEWIRRNVDDWEEAVVVSKNPGGAKRVTSLADTLNLDFALINTDRQRSSHFSQNFEDSIMDETEATETHVTNCSVYLDRPRIHTAKYLLGHIIDDEEIITTPASVCSEDYAQEVNLYSQGGCPSDDDEEENIMSASIYAERMITLVGDVNGKTALLIDDTIENPTAFIVASEHLVKRCGAKRVIVIGTHGIFQNKCLKDLQSCEYIEQIVVTNTYPIKPQAVLECDKLTVIDISGVLAEAIRRTHNGESISFLFKKAF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
199	Phosphorylation	INTDRQRSSHFSQNF EECCHHHCHHHCCCH	21.59	-
209	Phosphorylation	FSQNFEDSIMDETEA HCCCHHHHHCCCCCC	16.77	29996109
214	Phosphorylation	EDSIMDETEATETHV HHHHCCCCCCCCEEE	27.01	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of KPR1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of KPR1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of KPR1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of KPR1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of KPR1_SCHPO

Related Literatures of Post-Translational Modification