P25_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: P25_SCHPO
• UniProt AC: P30821
• Protein Name: P25 protein
• Gene Name: obr1
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 202
• Protein Description: Unknown. Target of pap1 transcription factor. Confers brefeldin A resistance in S.pombe..
• Protein Sequence: MSTANTVAIVIYSTYGHVVKLAEAEKAGIEKAGGKAVIYQFPETLSPEILEKMHAAPKPNYPVVTLDVLTQYDAFLFGYPTRYGTPPAQFRTFWDSTGGLWVQGALHGKYFGQFFSTGTLGGGQESTALTAMTSFVHHGMIFVPLGYKNTFSLMANVESIHGGSSWGAGSYAGADGSRNVSDDELEIARIQGETFFKTVFRK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
46	Phosphorylation	YQFPETLSPEILEKM EECCCCCCHHHHHHH	28.10	25720772
85	Phosphorylation	GYPTRYGTPPAQFRT CCCCCCCCCCHHHEE	19.71	28889911
181	Phosphorylation	ADGSRNVSDDELEIA CCCCCCCCCCHHHHH	42.78	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of P25_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of P25_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of P25_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
H2B1_SCHPO	htb1	physical	12511578
ELP5_SCHPO	elp5	genetic	18818364
YFE6_SCHPO	gmh5	genetic	18818364
AMO1_SCHPO	amo1	genetic	18818364
PUB1_SCHPO	pub1	genetic	22681890
HRP3_SCHPO	hrp3	genetic	22681890
SPP1_SCHPO	spf1	genetic	22681890
GLRX5_SCHPO	grx5	genetic	22681890
MUG80_SCHPO	mug80	genetic	22681890
RIA1_SCHPO	ria1	genetic	22681890
DTD_SCHPO	SPAC8C9.05	genetic	22681890
CYSK_SCHPO	cys11	genetic	22681890
P25_SCHPO	obr1	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-181, AND MASSSPECTROMETRY.
PubMed: 18257517