ZIP2_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZIP2_SCHPO
• UniProt AC: O94402
• Protein Name: Probable zinc transporter zip2
• Gene Name: zip2
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 389
• Subcellular Localization: Endoplasmic reticulum membrane ; Multi-pass membrane protein .
• Protein Description: Probable zinc transporter that may mediate zinc remobilization from the endoplasmic reticulum under zinc limitation..
• Protein Sequence: MNNSKGWILSLSINAFCVFGASGIYLDKLVNKWFGYEVLDLANSDNALVTGLATSSGILLYSSWASVMQESFHFLEKISMFDTFLVRVFQFCAFFFGGIVFYIFNHFLHKWLHESSQTGFLHDHFSVSDPSPSTAQNHRSPPASCKRLSSCESSGSPSSRVVGSLQGSYCPSGTHLHEGSLLLEDSSARHSSDSVHEYLVKKPSNCDCECHAHFSSFPTHSGTPDDIEHIHSVYTMGIQTALLICLHKVPEGFITFLASTVDTGFMVLVAMSIHNIVEGFTIAYPLYLAWKSRPKAFLTAATLSSCSLPLGSLIAFLVMEAGGIGSSDFLNFLYGIIFAGTAGMMLILSLRVILPEALRHDHSENKRHSFICFTIGILFTLFLEIFDSH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
149	Phosphorylation	PASCKRLSSCESSGS CHHCCCHHHCCCCCC	36.65	29996109
150	Phosphorylation	ASCKRLSSCESSGSP HHCCCHHHCCCCCCC	26.88	29996109
153	Phosphorylation	KRLSSCESSGSPSSR CCHHHCCCCCCCCHH	44.31	29996109
154	Phosphorylation	RLSSCESSGSPSSRV CHHHCCCCCCCCHHH	22.46	29996109
156	Phosphorylation	SSCESSGSPSSRVVG HHCCCCCCCCHHHCC	24.45	29996109
172	Phosphorylation	LQGSYCPSGTHLHEG CCCCCCCCCCCCCCC	53.41	27738172
174	Phosphorylation	GSYCPSGTHLHEGSL CCCCCCCCCCCCCCE	26.12	29996109
180	Phosphorylation	GTHLHEGSLLLEDSS CCCCCCCCEEECCCC	16.92	29996109
191	Phosphorylation	EDSSARHSSDSVHEY CCCCCCCCCCCHHHH	30.22	25720772
192	Phosphorylation	DSSARHSSDSVHEYL CCCCCCCCCCHHHHH	27.99	29996109
194	Phosphorylation	SARHSSDSVHEYLVK CCCCCCCCHHHHHCC	27.59	25720772
198	Phosphorylation	SSDSVHEYLVKKPSN CCCCHHHHHCCCCCC	11.25	29996109

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZIP2_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZIP2_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZIP2_SCHPO !!

Protein-Protein Interaction

Oops, there are no PPI records of ZIP2_SCHPO !!

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.