MBX1_SCHPO - dbPTM
MBX1_SCHPO - PTM Information in dbPTM
Basic Information of Protein
UniProt ID MBX1_SCHPO
UniProt AC O42954
Protein Name MADS-box transcription factor 1
Gene Name mbx1
Organism Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length 457
Subcellular Localization Nucleus .
Protein Description Acts as a transcriptional activator with a role in the regulation of mitosis. Regulates septation and the periodic transcription of cdc15..
Protein Sequence MDINPPPSTAPSSPRRSIQRISDAKNKALTFNRRRLGLIKKAHELSVLCDAKVVVMIFDSKNACHVYSSEEPEEQRDALLQKFLNKDFVTVDPLRNINPNIPSDESLHNWRPKDKRIASVTTYSAQPSNNCSSATDSENDFQSFTIKSSTTYHTTPTTASENKKIESITIPDHASVYNDLPLSPTVKHSFVSPVSGDYSDSPLEPSSSSSFSVPPESLNPTLSFQHNDVPQTDNFIPFLTPKRQAYGQSSSRADRSSVRRSQSFKNRRNGKPRISRLHTSHASIDGLTDFIQSPSSGYLDPSSTPITPLDSAINQITPPFLPDNLGQENRGELYSHDNPTSMVYEHPKFDELPNGFIDTHELNILSRSFTASPNQILRESNMVNQDSFTDNPVDATWDALIGTTQIDLDLDYERSSIPSSTIPADQLKDGVPTNSVYRNNMVDHNLYPSLNIERNAP
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
8PhosphorylationMDINPPPSTAPSSPR
CCCCCCCCCCCCCCC		42.8721712547
9PhosphorylationDINPPPSTAPSSPRR
CCCCCCCCCCCCCCH		48.6529996109
12PhosphorylationPPPSTAPSSPRRSIQ
CCCCCCCCCCCHHHH		50.9721712547
13PhosphorylationPPSTAPSSPRRSIQR
CCCCCCCCCCHHHHH		22.7421712547
17PhosphorylationAPSSPRRSIQRISDA
CCCCCCHHHHHHHHH		25.0921712547
128PhosphorylationTTYSAQPSNNCSSAT
EEEECCCCCCCCCCC		28.7025720772
133PhosphorylationQPSNNCSSATDSEND
CCCCCCCCCCCCCCC		37.0725720772
135PhosphorylationSNNCSSATDSENDFQ
CCCCCCCCCCCCCCC		41.8425720772
137PhosphorylationNCSSATDSENDFQSF
CCCCCCCCCCCCCCE		33.6625720772
175PhosphorylationITIPDHASVYNDLPL
EECCCCCHHCCCCCC		23.0124763107
177PhosphorylationIPDHASVYNDLPLSP
CCCCCHHCCCCCCCC		10.6421712547
183PhosphorylationVYNDLPLSPTVKHSF
HCCCCCCCCCCCEEC		19.3129996109
185PhosphorylationNDLPLSPTVKHSFVS
CCCCCCCCCCEECEE		38.5224763107
368PhosphorylationELNILSRSFTASPNQ
HHHHHHCCCCCCHHH		24.4725720772
370PhosphorylationNILSRSFTASPNQIL
HHHHCCCCCCHHHHH		27.7229996109
372PhosphorylationLSRSFTASPNQILRE
HHCCCCCCHHHHHHH		22.7128889911
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of MBX1_SCHPO !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of MBX1_SCHPO !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of MBX1_SCHPO !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
SEP1_SCHPOsep1genetic
15509866
FKH2_SCHPOfkh2genetic
15509866
FLP1_SCHPOclp1physical
21098641
ASL1_SCHPOasl1genetic
22681890
HRP3_SCHPOhrp3genetic
22681890
ALY2_SCHPOSPBC2D10.04genetic
22681890
YBD3_SCHPOSPBC16C6.03cgenetic
22681890
YIN2_SCHPOSPAC1705.02genetic
22681890
EIF2A_SCHPOSPBC4B4.04genetic
22681890
YGDH_SCHPOSPBC1773.17cgenetic
22681890
YEG9_SCHPOSPAC26H5.09cgenetic
22681890
YKTB_SCHPOSPAPB1E7.11cgenetic
22681890
IST1_SCHPOist1genetic
22681890
SNF5_SCHPOsnf5genetic
22681890
TPS1_SCHPOtps1genetic
22681890
ARP42_SCHPOarp42genetic
22681890
ASH2_SCHPOash2genetic
22681890
PSL1_SCHPOpsl1genetic
22681890
CYK3_SCHPOcyk3genetic
22681890
LSB5_SCHPOlsb5genetic
22681890
YE98_SCHPOerp2genetic
22681890
REC24_SCHPOrec24genetic
22681890
YFM8_SCHPOSPAC222.08cgenetic
22681890
ATG17_SCHPOatg17genetic
22681890
PDS5_SCHPOpds5genetic
22681890
YJ53_SCHPOSPCC4F11.03cgenetic
22681890
PTPA1_SCHPOypa1genetic
22681890
ETT1_SCHPOnro1genetic
22681890
ALM1_SCHPOalm1genetic
22681890
CGM2_SCHPOmcs2genetic
22681890
RL21B_SCHPOrpl2102genetic
22681890
YFE6_SCHPOgmh5genetic
22681890
MKH1_SCHPOmkh1genetic
22681890
CLR1_SCHPOclr1genetic
22681890
RL7B_SCHPOrpl702genetic
22681890
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of MBX1_SCHPO

loading...

Related Literatures of Post-Translational Modification
Phosphorylation
ReferencePubMed
"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-372, AND MASSSPECTROMETRY.

TOP
© 2024 Institute of Bioinformatics and Systems Biology, NYCU | Designed by : BiOmics Laboratory