dbPTM

OBP1_SCHPO - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	OBP1_SCHPO
UniProt AC	O94512
Protein Name	Oxysterol-binding protein-like protein 1
Gene Name	obp1
Organism	Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
Sequence Length	516
Subcellular Localization	Endoplasmic reticulum .
Protein Description
Protein Sequence	MPNPNQAIKKENEPIQVENPTELVRDDGEVEGYQKEEGKFKLVLSILKQCIGVKDIASLRFSLPAQLLEPVGNLEYWNYVDRPDYFAVMGDSDDELERMLGVLRWWFTKDLRFVRGRVVKPYNSVLGEFFRCKWVVTDPTVREDHTLDPDSSQLPTYKTEYSETTKFPLGKSYRPKASRTTSSQSVASTMTKSSTKTSKKKSSKKNSKSESNQDSSNDRSSTAPSTAESNNEHLSSSQKSKHSIVFMAEQTSHHPAVSAFYVTCPSKGIEVYGQDQIAVGFTGTSFKVCAGDLNKGVYVRFNKRDNEEYLCTHPSASVGGILRGNLHINLLDSTVILCPKTRIKTIITYIEERWLGKPRSLVEGVCYRYDPSNDTIDSIKAVPKENILATFKGNWRNCIFYSYAGESESRMLVDLNELDLVHKRCPPLDKQFPFESRKIWFPVTHNILAKHYTQATKAKQEIEDQQRQASAAREESHTEWKPRFFVPDEKEGRPTLTEEGKKVLEQSLSDEYIHGS

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
178	Phosphorylation	KSYRPKASRTTSSQS CCCCCCCCCCCCCHH	35.96	24763107
180	Phosphorylation	YRPKASRTTSSQSVA CCCCCCCCCCCHHHH	28.65	21712547
181	Phosphorylation	RPKASRTTSSQSVAS CCCCCCCCCCHHHHH	25.85	29996109
182	Phosphorylation	PKASRTTSSQSVAST CCCCCCCCCHHHHHH	26.26	28889911
183	Phosphorylation	KASRTTSSQSVASTM CCCCCCCCHHHHHHH	25.12	25720772
185	Phosphorylation	SRTTSSQSVASTMTK CCCCCCHHHHHHHCC	22.92	25720772
188	Phosphorylation	TSSQSVASTMTKSST CCCHHHHHHHCCCCC	19.29	21712547
191	Phosphorylation	QSVASTMTKSSTKTS HHHHHHHCCCCCCCC	28.06	21712547
215	Phosphorylation	KSESNQDSSNDRSST CCCCCCCCCCCCCCC	22.68	25720772
216	Phosphorylation	SESNQDSSNDRSSTA CCCCCCCCCCCCCCC	51.55	29996109
220	Phosphorylation	QDSSNDRSSTAPSTA CCCCCCCCCCCCCCH	34.60	25720772
221	Phosphorylation	DSSNDRSSTAPSTAE CCCCCCCCCCCCCHH	29.49	25720772
222	Phosphorylation	SSNDRSSTAPSTAES CCCCCCCCCCCCHHH	43.78	24763107
225	Phosphorylation	DRSSTAPSTAESNNE CCCCCCCCCHHHCCC	37.47	24763107
226	Phosphorylation	RSSTAPSTAESNNEH CCCCCCCCHHHCCCC	33.13	25720772
229	Phosphorylation	TAPSTAESNNEHLSS CCCCCHHHCCCCCCC	42.35	29996109
235	Phosphorylation	ESNNEHLSSSQKSKH HHCCCCCCCCCCCCC	29.83	29996109
236	Phosphorylation	SNNEHLSSSQKSKHS HCCCCCCCCCCCCCE	43.05	29996109
237	Phosphorylation	NNEHLSSSQKSKHSI CCCCCCCCCCCCCEE	37.95	29996109
516	Phosphorylation	SDEYIHGS------- CCCCCCCC-------	23.92	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of OBP1_SCHPO !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of OBP1_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of OBP1_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
Oops, there are no PPI records of OBP1_SCHPO !!

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of OBP1_SCHPO

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Phosphoproteome analysis of fission yeast."; Wilson-Grady J.T., Villen J., Gygi S.P.; J. Proteome Res. 7:1088-1097(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-182, AND MASSSPECTROMETRY.	18257517 [Abstract]