| UniProt ID | RTN1_SCHPO | |
|---|---|---|
| UniProt AC | P53694 | |
| Protein Name | Reticulon-like protein 1 | |
| Gene Name | rtn1 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 308 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Multi-pass membrane protein . Nucleus membrane Multi-pass membrane protein . Enriched at the cell equator during mitosis. |
|
| Protein Description | Required for the correct positioning of the cellular division plane by delimiting the actomyosin ring assembly at the cell equator. Overexpression causes cell lysis.. | |
| Protein Sequence | MSEQHSLNPFESGSVTASDVAAAKSGAEDLVNTLTAHTVHPSTELPSATSFPSALPNSENPVIQNISSSSSEPHHTSQSTPGETSSPVCPVSGAHGGADKKCPALEAGCPFTNTTKQNVDPEISNALWSVLTWKNTSCSFSTLMSILALVYVPSWINLPRLFFRTFRYVFLITSIIEFGGLFASNGKRGVLSHFRSSYITCDSKALDRIVNSIVDIFNVMLIQFQRILFAESPILTFTASVAAFIEFFLSGFLSYKSLFVWNVLFAFILPRLYVCNERSIKHLVASLERSGDKLKKQATETINTTVNK | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 2 | Phosphorylation | ------MSEQHSLNP ------CCCCCCCCC | 46.06 | 24763107 | |
| 6 | Phosphorylation | --MSEQHSLNPFESG --CCCCCCCCCCCCC | 29.54 | 21712547 | |
| 12 | Phosphorylation | HSLNPFESGSVTASD CCCCCCCCCCCCHHH | 36.43 | 21712547 | |
| 14 | Phosphorylation | LNPFESGSVTASDVA CCCCCCCCCCHHHHH | 26.10 | 28889911 | |
| 16 | Phosphorylation | PFESGSVTASDVAAA CCCCCCCCHHHHHHH | 23.34 | 21712547 | |
| 18 | Phosphorylation | ESGSVTASDVAAAKS CCCCCCHHHHHHHHC | 24.21 | 29996109 | |
| 65 | N-linked_Glycosylation | SENPVIQNISSSSSE CCCCCEECCCCCCCC | 25.61 | - | |
| 113 | N-linked_Glycosylation | EAGCPFTNTTKQNVD HCCCCCCCCCCCCCC | 46.24 | - | |
| 135 | N-linked_Glycosylation | WSVLTWKNTSCSFST HHHHHCCCCCCHHHH | 28.87 | - | |
| 192 | Phosphorylation | NGKRGVLSHFRSSYI CCCCCHHHHHHHCCC | 20.41 | 25720772 | |
| 196 | Phosphorylation | GVLSHFRSSYITCDS CHHHHHHHCCCCCCH | 26.92 | 25720772 | |
| 197 | Phosphorylation | VLSHFRSSYITCDSK HHHHHHHCCCCCCHH | 19.12 | 25720772 | |
| 303 | N-linked_Glycosylation | KQATETINTTVNK-- HHHHHHHHHHCCC-- | 36.80 | - |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of RTN1_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of RTN1_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of RTN1_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| PST2_SCHPO | pst2 | genetic | 19547744 | |
| YH75_SCHPO | scs2 | genetic | 23041194 | |
| YDFC_SCHPO | scs22 | genetic | 23041194 | |
| RTN1_SCHPO | rtn1 | physical | 26771498 | |
| TVP18_SCHPO | SPBC32F12.12c | physical | 26771498 | |
| DGK1_SCHPO | ptp4 | physical | 26771498 | |
| YHOE_SCHPO | SPBC428.14 | physical | 26771498 | |
| YGW2_SCHPO | vps68 | physical | 26771498 | |
| YOP1_SCHPO | yop1 | physical | 26771498 | |
| SURF4_SCHPO | SPCC970.06 | physical | 26771498 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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