| UniProt ID | SWI3_SCHPO | |
|---|---|---|
| UniProt AC | O14350 | |
| Protein Name | Swi1-interacting protein swi3 | |
| Gene Name | swi3 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 181 | |
| Subcellular Localization | Nucleus . Nuclear throughout the cell cycle. Associated with chromatin during S phase. | |
| Protein Description | Forms a fork protection complex (FPC) with swi1. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. It is required for programmed fork-pausing which is necessary for mating-type switching. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors. It is involved in termination at the mat1-proximal polar-terminator of replication (RTS1) and also required for activation of the Rad53-like checkpoint kinase cds1.. | |
| Protein Sequence | MSTAASDSGVEKLVEENKREEVKKNEEEKEFDLGLEENPDSVKKPRKRLAKFDEERLISENGIPKLRKMMRKVKLKGKGHEAKDLKQLLGMYHIWTHELYPRATFDDSISYLKTLGKHRSVKVRRRGWINEIAVENGSDSNASLFTGPSSNSLVNLTSGDPYVQDTADDAFVAQDNDTQLE | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|
|---|---|---|---|---|---|---|
Oops, there are no PTM records of SWI3_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SWI3_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SWI3_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SWI3_SCHPO !! | ||||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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