UniProt ID | THI22_SCHPO | |
---|---|---|
UniProt AC | O94266 | |
Protein Name | Putative hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 2 | |
Gene Name | SPBP8B7.18c | |
Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
Sequence Length | 551 | |
Subcellular Localization | Cytoplasm . | |
Protein Description | Catalyzes the phosphorylation of hydroxymethylpyrimidine phosphate (HMP-P) to HMP-PP, and of HMP to HMP-P.. | |
Protein Sequence | MPYNPLYESLSNQFDPSRIETVLDPMGYTIKRRALPVSLTIAGSDCSGGAGIQADLKTMTSLGVYGMSAITCLVAENAGGVDSVEEMSPAFVESQIDCCIRDIPCHVVKTGMLGSPEIVKAVARSAKKFNFSKLVVDPVMVATSGDSLVTKDIVSVLNEELLPLTYLVTPNIPEAIVLAKNQGLDISNINSVSDMERCAAVIHKLGPKHVLLKGGHMPVNNLGLKSSDDEDLRVVDILYDGNRFYHFSSSYLKKGEVHGTGCTLSSAIASFLAWEHSLTEAVQFGIDYVHGAITHSPPINNCSTNILNHMTRLRIVPFAPGHFIEYILSHPQVVPAWKEYINHKFTNMLAKGTLPLPAFQDYLKQDYLYLVNFARAYSLKGYKENTFPNILEAAQSVIHVIEEKELHVSMCSSYGVSLQDLKSCEESPACTAYSRYILDTGAAQDVAALDFVQAPCLIGYYVIAARLMKEPFRNPQGPYQKWVDNYFCEDYLSAVRRGCRQIEEIVLKLSPERIQELIEIFIRATKFETLFWETPYYEYVTKQNLEDKEFS | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
115 | Phosphorylation | VKTGMLGSPEIVKAV EECCCCCCHHHHHHH | 18.52 | 25720772 | |
226 | Phosphorylation | VNNLGLKSSDDEDLR CCCCCCCCCCCCCCE | 44.00 | 25720772 | |
227 | Phosphorylation | NNLGLKSSDDEDLRV CCCCCCCCCCCCCEE | 47.71 | 25720772 | |
433 | Phosphorylation | ESPACTAYSRYILDT CCCCCCHHHHHEECC | 3.89 | 25720772 | |
551 | Phosphorylation | NLEDKEFS------- CCCCCCCC------- | 40.16 | 25720772 |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of THI22_SCHPO !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of THI22_SCHPO !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of THI22_SCHPO !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
RIK1_SCHPO | rik1 | genetic | 18818364 | |
SWC5_SCHPO | swc5 | genetic | 18818364 | |
YHZ8_SCHPO | SPBC21B10.08c | genetic | 22681890 | |
THI9_SCHPO | thi9 | genetic | 22681890 | |
YH51_SCHPO | SPBC215.01 | genetic | 22681890 | |
ADH4_SCHPO | adh4 | genetic | 22681890 | |
PSL1_SCHPO | psl1 | genetic | 22681890 | |
ATG20_SCHPO | atg20 | genetic | 22681890 | |
ALAT_SCHPO | SPBC582.08 | genetic | 22681890 | |
YHZ7_SCHPO | SPBC21B10.07 | genetic | 22681890 | |
THI22_SCHPO | SPBP8B7.18c | physical | 26771498 |
Kegg Drug | ||||||
---|---|---|---|---|---|---|
DrugBank | ||||||
There are no disease associations of PTM sites. |
loading...