| UniProt ID | THI9_SCHPO | |
|---|---|---|
| UniProt AC | Q9UT18 | |
| Protein Name | Thiamine transporter thi9 | |
| Gene Name | thi9 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 591 | |
| Subcellular Localization |
Endoplasmic reticulum membrane Multi-pass membrane protein. Cell membrane Multi-pass membrane protein. |
|
| Protein Description | Thiamine transporter involved in the cellular uptake of thiamine. Pyrithiamine, oxythiamine, amprolium, and the thiazole part of thiamine have been shown to be also substrates of thi9.. | |
| Protein Sequence | MPSSQISHQDPELGQTSSGSSSIKEKAEPQLYAGPIDPARRPDVFQEGFEDVSVTDDDNDNELLRKMGYQPVLHRSFEFFESFAASFASLDVVSGVRLTFSWGISFGGPAAYWSAMLVTGFCSIVTAACLAEICSALPAAGSIYLWAAESAGPRFGRFVSFLVAWWSTTAWTTFVASITQSTANFIFAEVSTFNNPWPTNDSDVKFRAVQWIVAEVLLVFTILLNQVPPRYYKWIFKASMLLMFIDYVMNIIWVPVATSKKPDGFRSAKWVFTETIYDQAGYIKEVDDANGNPIASLSKIVPKGWQWCLSYFATAGVIVGYDASGHIAEETKDASIKAARGIFYSTVTSFIVAFSLAILYLFCCPDLDTFTAILYNDNSPQPFVNFYSYLLGRGGHVVMNVVIILEIFLNGVVSVLACSRLVFAVSRDGVLPFSNWISQVSKTGQPKNAITVIYIVSALLLCTILPSAVAFTSLVSAAGAPSFAAYAVLAFCRLFITRDKFPKGRWSLGWLSKPCLVITLVYNLFALVVNVSPYTYPVTGPSFNYAVVIMGGVSIFAIICTIVIPKSRWVANRYRYESDSEHSASVKELKV | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 3 | Phosphorylation | -----MPSSQISHQD -----CCHHHCCCCC | 29996109 | ||
| 4 | Phosphorylation | ----MPSSQISHQDP ----CCHHHCCCCCC | 29996109 | ||
| 7 | Phosphorylation | -MPSSQISHQDPELG -CCHHHCCCCCCCCC | 29996109 | ||
| 16 | Phosphorylation | QDPELGQTSSGSSSI CCCCCCCCCCCCHHH | 21712547 | ||
| 17 | Phosphorylation | DPELGQTSSGSSSIK CCCCCCCCCCCHHHH | 24763107 | ||
| 18 | Phosphorylation | PELGQTSSGSSSIKE CCCCCCCCCCHHHHH | 24763107 | ||
| 20 | Phosphorylation | LGQTSSGSSSIKEKA CCCCCCCCHHHHHHC | 24763107 | ||
| 21 | Phosphorylation | GQTSSGSSSIKEKAE CCCCCCCHHHHHHCC | 24763107 | ||
| 22 | Phosphorylation | QTSSGSSSIKEKAEP CCCCCCHHHHHHCCC | 24763107 | ||
| 32 | Phosphorylation | EKAEPQLYAGPIDPA HHCCCCCCCCCCCHH | 21712547 | ||
| 53 | Phosphorylation | QEGFEDVSVTDDDND HCCCCCCCCCCCCCH | 25720772 | ||
| 55 | Phosphorylation | GFEDVSVTDDDNDNE CCCCCCCCCCCCHHH | 29996109 | ||
| 574 | Phosphorylation | SRWVANRYRYESDSE HHHHHHCCCCCCCCC | 25720772 | ||
| 576 | Phosphorylation | WVANRYRYESDSEHS HHHHCCCCCCCCCCC | 25720772 | ||
| 578 | Phosphorylation | ANRYRYESDSEHSAS HHCCCCCCCCCCCCC | 29996109 | ||
| 580 | Phosphorylation | RYRYESDSEHSASVK CCCCCCCCCCCCCHH | 29996109 | ||
| 583 | Phosphorylation | YESDSEHSASVKELK CCCCCCCCCCHHHCC | 29996109 | ||
| 585 | Phosphorylation | SDSEHSASVKELKV- CCCCCCCCHHHCCC- | 28889911 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of THI9_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of THI9_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of THI9_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
Oops, there are no PPI records of THI9_SCHPO !! | ||||
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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