| UniProt ID | DPOD_SCHPO | |
|---|---|---|
| UniProt AC | P30316 | |
| Protein Name | DNA polymerase delta catalytic subunit | |
| Gene Name | pol3 | |
| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). | |
| Sequence Length | 1086 | |
| Subcellular Localization | Nucleus. | |
| Protein Description | This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction.. | |
| Protein Sequence | MTDRSSNEGVVLNKENYPFPRRNGSIHGEITDVKRRRLSERNGYGDKKGSSSKEKTSSFEDELAEYASQLDQDEIKSSKDQQWQRPALPAINPEKDDIYFQQIDSEEFTEGSVPSIRLFGVTDNGNSILVHVVGFLPYFYVKAPVGFRPEMLERFTQDLDATCNGGVIDHCIIEMKENLYGFQGNEKSPFIKIFTTNPRILSRARNVFERGEFNFEELFPVGVGVTTFESNTQYLLRFMIDCDVVGMNWIHLPASKYQFRYQNRVSNCQIEAWINYKDLISLPAEGQWSKMAPLRIMSFDIECAGRKGVFPDPSIDPVIQIASIVTQYGDSTPFVRNVFCVDTCSQIVGTQVYEFQNQAEMLSSWSKFVRDVDPDVLIGYNICNFDIPYLLDRAKSLRIHNFPLLGRIHNFFSVAKETTFSSKAYGTRESKTTSIPGRLQLDMLQVMQRDFKLRSYSLNAVCSQFLGEQKEDVHYSIITDLQNGTADSRRRLAIYCLKDAYLPQRLMDKLMCFVNYTEMARVTGVPFNFLLARGQQIKVISQLFRKALQHDLVVPNIRVNGTDEQYEGATVIEPIKGYYDTPIATLDFSSLYPSIMQAHNLCYTTLLDSNTAELLKLKQDVDYSVTPNGDYFVKPHVRKGLLPIILADLLNARKKAKADLKKETDPFKKAVLDGRQLALKVSANSVYGFTGATNGRLPCLAISSSVTSYGRQMIEKTKDVVEKRYRIENGYSHDAVVIYGDTDSVMVKFGVKTLPEAMKLGEEAANYVSDQFPNPIKLEFEKVYFPYLLISKKRYAGLFWTRTDTYDKMDSKGIETVRRDNCPLVSYVIDTALRKMLIDQDVEGAQLFTKKVISDLLQNKIDMSQLVITKALSKTDYAAKMAHVELAERMRKRDAGSAPAIGDRVAYVIIKGAQGDQFYMRSEDPIYVLENNIPIDAKYYLENQLSKPLLRIFEPILGEKASSLLHGDHTRTISMAAPSVGGIMKFAVKVETCLGCKAPIKKGKTALCENCLNRSAELYQRQVAQVNDLEVRFARLWTQCQRCQGSMHQDVICTSRDCPIFYMRIAEHKKLQQSVDLLKRFDEMSW | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 5 | Phosphorylation | ---MTDRSSNEGVVL ---CCCCCCCCCEEE | 40.08 | 24763107 | |
| 6 | Phosphorylation | --MTDRSSNEGVVLN --CCCCCCCCCEEEC | 39.53 | 21712547 | |
| 25 | Phosphorylation | PFPRRNGSIHGEITD CCCCCCCCCCCCCCH | 18.24 | 29996109 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of DPOD_SCHPO !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of DPOD_SCHPO !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of DPOD_SCHPO !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| DPOD4_SCHPO | cdm1 | genetic | 9799358 | |
| RAD3_SCHPO | rad3 | genetic | 9154809 | |
| RAD26_SCHPO | rad26 | genetic | 9154809 | |
| CDK1_SCHPO | cdc2 | genetic | 9154809 | |
| CHK1_SCHPO | chk1 | genetic | 9154809 | |
| CHK1_SCHPO | chk1 | genetic | 14739927 | |
| DPOD2_SCHPO | cdc1 | physical | 15173383 | |
| HUS1_SCHPO | hus1 | genetic | 9135148 | |
| RAD1_SCHPO | rad1 | genetic | 9135148 | |
| CHK1_SCHPO | chk1 | genetic | 9135148 | |
| CDK1_SCHPO | cdc2 | genetic | 9135148 | |
| DPOD3_SCHPO | cdc27 | physical | 19686603 | |
| MUS81_SCHPO | mus81 | genetic | 11073977 | |
| RHP9_SCHPO | crb2 | genetic | 9407031 | |
| SET1_SCHPO | set1 | genetic | 12589755 | |
| RHP9_SCHPO | crb2 | genetic | 14739927 | |
| FEN1_SCHPO | rad2 | genetic | 9891047 | |
| CDS1_SCHPO | cds1 | genetic | 9891047 | |
| HUS2_SCHPO | rqh1 | genetic | 9891047 | |
| AP1_SCHPO | pap1 | genetic | 24587136 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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